Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 28 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA04G025910
TK1151: TkA04G025910;TkA04G025950
OH-1004: LXL04_036752
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:47910683-47912337
+
GO:0016114
TkA04G016480
TK1151: TkA04G016480;TkA08G118570;TkA08G121190
OH-1004: LXL04_036936
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:50348150-50352355
-
GO:0016740
TkA04G007210
TK1151: TkA04G007210;TkA04G048220;TkA04G048460;TkA04G048470
OH-1004: LXL04_037063
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:52498714-52505736
-
GO:0016740
TkA01G444990
TK1151: TkA01G444990;TkA02G602440;TkA04G140090;TkA04G304850;TkA05G034120
OH-1004: LXL04_037394
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:9128946-9131515
+
GO:0016740
LXL04_037620
TK1151: -
OH-1004: LXL04_037620
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-Prot CM104807.1:16327381-16327879
-
GO:0008299
LXL04_037635
TK1151: -
OH-1004: LXL04_037635
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:16803609-16805784
+
GO:0016740
TkA04G358450
TK1151: TkA04G358450
OH-1004: LXL04_037890
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:24463156-24467226
+
GO:0016740
LXL04_037944
TK1151: -
OH-1004: LXL04_037944
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:25923792-25925584
+
GO:0008299
TkA04G407790
TK1151: TkA04G407790;TkA07G356280
OH-1004: LXL04_038226
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104807.1:34678654-34682672
+
GO:0016740
LXL04_038304
TK1151: -
OH-1004: LXL04_038304
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104807.1:36915774-36916379
-
GO:0016114

TkA04G025910

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G025910;TkA04G025950
LocationCM104806.1:47910683-47912337 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA04G016480

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G016480;TkA08G118570;TkA08G121190
LocationCM104806.1:50348150-50352355 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA04G007210

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G007210;TkA04G048220;TkA04G048460;TkA04G048470
LocationCM104806.1:52498714-52505736 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA01G444990

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G444990;TkA02G602440;TkA04G140090;TkA04G304850;TkA05G034120
LocationCM104807.1:9128946-9131515 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_037620

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104807.1:16327381-16327879 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidenceGO:0008299

LXL04_037635

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104807.1:16803609-16805784 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA04G358450

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G358450
LocationCM104807.1:24463156-24467226 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_037944

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104807.1:25923792-25925584 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA04G407790

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G407790;TkA07G356280
LocationCM104807.1:34678654-34682672 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_038304

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104807.1:36915774-36916379 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.