TkA08G266700 | RubberDandelionOmics

Gene overview

TkA08G266700

Reference: TK1151 Chr: Chr08 Coordinates: 69499724-69510913 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

3192 bp · TkA08G266700|TK1151|cDNA

CAAGCACAAAGGCGGGAAAAGCATGTCTTTGGTTCCTAAAGACTAAAACCCCAAAAAGGTTTGAACAGAGAGGCAGTAACGTAGTCGGATTAAACTCCCCGGCAATAATATGGCGGCGGGAGGCGGCGGAGGGAGGGCAATCAGGGTGCTGAATGTGGCGGAGAAGCCGTCGGTGGCAAAGACGGTATCGGGAATATTATCGAGGAACCAGGGGTTGAGAACGCGAGAGGGGCGGTCAAGGTACAACAAAGTGTTCGAGT...

CDS

Download CDS FASTA

2844 bp · TkA08G266700|TK1151|CDS

ATGGCGGCGGGAGGCGGCGGAGGGAGGGCAATCAGGGTGCTGAATGTGGCGGAGAAGCCGTCGGTGGCAAAGACGGTATCGGGAATATTATCGAGGAACCAGGGGTTGAGAACGCGAGAGGGGCGGTCAAGGTACAACAAAGTGTTCGAGTTCAATTACACGATTCAAGGGCAGCCTTGCCAGATGCTCTTCACGTCCGTGACTGGACATCTCATGGAAATAGAGTTTGAAAGCCGCTATCGGAAGTGGAGCTCTTGCGA...

Protein

Download Protein FASTA

947 aa · TkA08G266700|TK1151|PROTEIN

MAAGGGGGRAIRVLNVAEKPSVAKTVSGILSRNQGLRTREGRSRYNKVFEFNYTIQGQPCQMLFTSVTGHLMEIEFESRYRKWSSCDPVDLFQAPIRKHVPEDKLDIKKTLEEEARKCQWLVLWLDCDREGENIAFEVVEVCSTANSHLNIWRARFSSLIEREIHQAAQQLQRPNQLFSDAVDVRQEIDLRIGASFTRFQTMLLKDAFVFNFSTDGRNLVLSYGPCQFPTLGFVVERYWEIQAHEPEEFWKIQCTHTADE...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA08G266700`
TK1151 ID	TkA08G266700
OH-1004 ID	LXL04_033479
Relationship / confidence	Rbh High Identity Coverage Synteny / Strict
Protein identity (%)	95.900
Protein coverage (%)	TK1151 100.000 / OH-1004 100.000 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

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Basic Information and Functional Annotation

Gene ID TkA08G266700

Location Chr08:69499724-69510913 (+)

Description Similar to TOP3A: DNA topoisomerase 3-alpha

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At5g63920`	Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.	No verified direct reference in this release

Rice

Reference gene ID	Possible function	Papers / DOI
`Os03g0165000`	Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.	No verified direct reference in this release

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_033479 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0000278 mitotic cell cycle Biological Process

GO:0000712 resolution of meiotic recombination intermediates Biological Process

GO:0000724 double-strand break repair via homologous recombination Biological Process

GO:0006265 DNA topological change Biological Process

GO:0006281 DNA repair Biological Process

GO:0006310 DNA recombination Biological Process

GO:0007059 chromosome segregation Biological Process

GO:0032042 mitochondrial DNA metabolic process Biological Process

GO:0051304 chromosome separation Biological Process

GO:0051321 meiotic cell cycle Biological Process

GO:0071139 resolution of DNA recombination intermediates Biological Process

GO:0005634 nucleus Cellular Component

KEGG gene cross-reference

ath:AT5G63920

ddi:DDB_G0275257

dosa:Os03g0165000

hsa:7156

mmu:21975

osa:9269718

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Nucleus0.740

Rank 1 · TkA08G266700 · TK1151

Cytoplasm0.335

Rank 2 · TkA08G266700 · TK1151

Mitochondrion0.074

Rank 3 · TkA08G266700 · TK1151

Cell membrane0.035

Rank 4 · TkA08G266700 · TK1151

Endoplasmic reticulum0.028

Rank 5 · TkA08G266700 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF01751Toprim14-158 aa

PF01131Topoisom_bac175-593 aa

PF01396Zn_ribbon_Top1640-678 aa

PF10428SOG2743-838 aa

PF16588zf-C2H2_10791-809 aa

PF00098zf-CCHC795-808 aa

PF06839Zn_ribbon_GRF835-875 aa

PF00098zf-CCHC835-841 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA08G266700	`PF01751`	Toprim	14	158	5.2e-12	46.5
TkA08G266700	`PF01131`	Topoisom_bac	175	593	1.2e-108	364.5
TkA08G266700	`PF01396`	Zn_ribbon_Top1	640	678	7.5e-09	36.0
TkA08G266700	`PF10428`	SOG2	743	838	5.6	7.0
TkA08G266700	`PF16588`	zf-C2H2_10	791	809	0.058	13.9
TkA08G266700	`PF00098`	zf-CCHC	795	808	0.39	11.6
TkA08G266700	`PF06839`	Zn_ribbon_GRF	835	875	1.6e-08	35.3
TkA08G266700	`PF00098`	zf-CCHC	835	841	0.39	11.6
TkA08G266700	`PF01396`	Zn_ribbon_Top1	836	862	7.5e-09	36.0
TkA08G266700	`PF00098`	zf-CCHC	926	942	0.39	11.6

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

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Protein	Organism	Description	Identity	Database	Confidence
`Q9LVP1`	Arabidopsis thaliana	sp\|Q9LVP1\|TOP3A_ARATH DNA topoisomerase 3-alpha	65.600%	Swiss-Prot	High
`C7J0A2`	Oryza sativa subsp. japonica	sp\|C7J0A2\|TOP3A_ORYSJ DNA topoisomerase 3-alpha	64.900%	Swiss-Prot	High

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