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基因详情

输入 TK1151 或 OH-1004 基因 ID，查看对应参考版本的序列、功能注释与分析结果。
上下游长度，最大 10000 bp
示例 TkA01G624900 LXL04_000258

基因概览

TkA05G251580
当前版本: TK1151 染色体: Chr05 坐标: 62546259-62551734 链方向: + 类型: protein_coding

cDNA / CDS / 蛋白序列

可用序列下载 CDS FASTA 蛋白 FASTA cDNA FASTA

cDNA

下载 cDNA FASTA

4199 bp · TkA05G251580|TK1151|cDNA

TGGATGGAGATTGGAAGTAAGGATAGAGATAATGGGCTATGCCAGAGGACATTTTTACAACCATATTCTCCTCATCTTTGCTTTTACAGATGCTTTACAACTTTCTCTCTCTCTCTCTCTCCCTCTCTCTCTCTCTCTCTCTCTCATAGTCCCCATTCCTTCGATCATTTTAGATTCATTGATTACCCACTCGAGATCTTAGAGTAAAATCGTTCAAATAGTTACTCACGTTCCTTGGTTTTTAGCTCATAATTATAGCA...

CDS

下载 CDS FASTA

2778 bp · TkA05G251580|TK1151|CDS

ATGAAGTTTGTGGAGATCTTTTCAGGGAACGCTTGTAAGATCCATCATCACTACTACCAATATATTAGTTCGAGGGAAGTTAGAAAAACATGGTCAAGGAAGCTCTTGATCTTATGGTTCGTATTTGGTACAATTCTGTCTTTGTGGTTCTTCTGGTATCTGAGATCTCAAGCCATGGAAAAGAGGAAAGAAACATTAGCAAATATGTGCGATGAAAGAGCTAGAATGCTTCAAGATCAGTTCAATGTCAGCATGAATCA...

蛋白

下载 蛋白 FASTA

925 aa · TkA05G251580|TK1151|PROTEIN

MKFVEIFSGNACKIHHHYYQYISSREVRKTWSRKLLILWFVFGTILSLWFFWYLRSQAMEKRKETLANMCDERARMLQDQFNVSMNHVQAMSILISTFHHGKTPSAIDQETFAKYTERTAFERPLTSGVAYAVRVLDSERQEFEKQQGWSIKKMTPVNKDEYNPEELEPSPIQQEYAPVIFAQDTVAHVISLDMMSGKEDRENVLRARALGKGVLTAPLDLIKSNRLGVILTFAVYKRDLPSNATPEERIEATDGYLGGV...

上下游序列下载

序列方向与下载说明

上游/下游最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

仅下载基因 CDS 下载蛋白序列

多版本 ID 对照

输入 IDTkA05G251580
TK1151 IDTkA05G251580
OH-1004 IDLXL04_022485
关系 / 置信度跨参考版本对应关系 / 复杂对应关系
蛋白一致性 (%)55.500
蛋白覆盖度 (%)TK1151 96.865 / OH-1004 95.388
覆盖度与证据说明

覆盖度为最高分比对片段的序列跨度占代表蛋白长度的比例。同源匹配不等同于功能验证。

版本TK1151 / GWHBCHF00000000
查看完整 ID 对照表
SNP / Indel 变异与样本携带情况CRA009020 · TK1151

展开后加载该基因的变异记录。

基因基本信息与功能注释

基因 IDTkA05G251580
位置Chr05:62546259-62551734 (+)
描述Similar to AHK4: Histidine kinase 4
拟南芥 / 水稻参考基因与文献

下载当前基因文献

拟南芥

参考基因 ID可能功能对应论文 / DOI
At1g27320 与细菌双组分调节剂相关的细胞分裂素 受体。
Novel family of sensor histidine kinase genes in Arabidopsis thaliana.2001 · DOI: 10.1093/pcp/pce015
The Arabidopsis AHK4 histidine kinase is a cytokinin-binding receptor that transduces cytokinin signals across the membrane.2001 · DOI: 10.1093/pcp/pce127
Histidine kinase homologs that act as cytokinin receptors possess overlapping functions in the regulation of shoot and root growth in Arabidopsis.2004 · DOI: 10.1105/tpc.021477
In planta functions of the Arabidopsis cytokinin receptor family.2004 · DOI: 10.1073/pnas.0402887101
Two cytokinin receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, differ in their ligand specificity in a bacterial assay.2004 · DOI: 10.1093/pcp/pch132
Interaction between phosphate-starvation, sugar, and cytokinin signaling in Arabidopsis and the roles of cytokinin receptors CRE1/AHK4 and AHK3.2005 · DOI: 10.1104/pp.105.060517
Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism.2006 · DOI: 10.1105/tpc.105.037796
Cytokinin-mediated control of leaf longevity by AHK3 through phosphorylation of ARR2 in Arabidopsis.2006 · DOI: 10.1073/pnas.0505150103
Cytokinins regulate a bidirectional phosphorelay network in Arabidopsis.2006 · DOI: 10.1016/j.cub.2006.04.030
Biochemical characteristics and ligand-binding properties of Arabidopsis cytokinin receptor AHK3 compared to CRE1/AHK4 as revealed by a direct binding assay.2006 · DOI: 10.1093/jxb/erl179
Identification of amino acid substitutions that render the Arabidopsis cytokinin receptor histidine kinase AHK4 constitutively active.2007 · DOI: 10.1093/pcp/pcm145
Cytokinin receptors are involved in alkamide regulation of root and shoot development in Arabidopsis.2007 · DOI: 10.1104/pp.107.107953
Functional analysis of AHK1/ATHK1 and cytokinin receptor histidine kinases in response to abscisic acid, drought, and salt stress in Arabidopsis.2007 · DOI: 10.1073/pnas.0706547105
Cytokinins negatively regulate the root iron uptake machinery in Arabidopsis through a growth-dependent pathway.2008 · DOI: 10.1111/j.1365-313x.2008.03502.x
Mechanism-based inhibitors of cytokinin oxidase/dehydrogenase attack FAD cofactor.2008 · DOI: 10.1016/j.jmb.2008.05.044
The histidine kinases CYTOKININ-INDEPENDENT1 and ARABIDOPSIS HISTIDINE KINASE2 and 3 regulate vascular tissue development in Arabidopsis shoots.2009 · DOI: 10.1105/tpc.109.066696
Cytokinin overproduction-caused alteration of flower development is partially mediated by CUC2 and CUC3 in Arabidopsis.2010 · DOI: 10.1016/j.gene.2009.11.003
A subset of cytokinin two-component signaling system plays a role in cold temperature stress response in Arabidopsis.2010 · DOI: 10.1074/jbc.m109.096644
At5g35750 与细菌双组分调节剂相关的细胞分裂素 受体。
Histidine kinase homologs that act as cytokinin receptors possess overlapping functions in the regulation of shoot and root growth in Arabidopsis.2004 · DOI: 10.1105/tpc.021477
In planta functions of the Arabidopsis cytokinin receptor family.2004 · DOI: 10.1073/pnas.0402887101
Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism.2006 · DOI: 10.1105/tpc.105.037796
Cytokinins regulate a bidirectional phosphorelay network in Arabidopsis.2006 · DOI: 10.1016/j.cub.2006.04.030
Identification of amino acid substitutions that render the Arabidopsis cytokinin receptor histidine kinase AHK4 constitutively active.2007 · DOI: 10.1093/pcp/pcm145
Cytokinin receptors are involved in alkamide regulation of root and shoot development in Arabidopsis.2007 · DOI: 10.1104/pp.107.107953
Functional analysis of AHK1/ATHK1 and cytokinin receptor histidine kinases in response to abscisic acid, drought, and salt stress in Arabidopsis.2007 · DOI: 10.1073/pnas.0706547105
The role of auxins and cytokinins in the mutualistic interaction between Arabidopsis and Piriformospora indica.2008 · DOI: 10.1094/mpmi-21-10-1371
The histidine kinases CYTOKININ-INDEPENDENT1 and ARABIDOPSIS HISTIDINE KINASE2 and 3 regulate vascular tissue development in Arabidopsis shoots.2009 · DOI: 10.1105/tpc.109.066696
Cytokinin overproduction-caused alteration of flower development is partially mediated by CUC2 and CUC3 in Arabidopsis.2010 · DOI: 10.1016/j.gene.2009.11.003
A subset of cytokinin two-component signaling system plays a role in cold temperature stress response in Arabidopsis.2010 · DOI: 10.1074/jbc.m109.096644

水稻

参考基因 ID可能功能对应论文 / DOI
UniProt: A2WYI4 与细菌双组分调控器相关的细胞分裂素受体。 暂无已核实直接文献
Os01g0923700 与细菌双组分调控器相关的细胞分裂素受体。 暂无已核实直接文献
Os10g0362300 与细菌双组分调控器相关的细胞分裂素受体。 暂无已核实直接文献
功能注释来源
查看注释来源

功能注释来源：OH1004 · LXL04_022485 · GCA_047496595.1_OSU_TarKok_2.0。此处为经 ID 对照查得的 OH1004 注释；下方拟南芥/水稻同源表使用当前查询参考的独立蛋白比对。

GO 注释（OH1004 来源）
GO:0000160 phosphorelay signal transduction system 生物过程
GO:0006468 protein phosphorylation 生物过程
GO:0006970 response to osmotic stress 生物过程
GO:0007231 osmosensory signaling pathway 生物过程
GO:0009414 response to water deprivation 生物过程
GO:0009636 response to toxic substance 生物过程
GO:0009651 response to salt stress 生物过程
GO:0009736 cytokinin-activated signaling pathway 生物过程
GO:0009737 response to abscisic acid 生物过程
GO:0009909 regulation of flower development 生物过程
GO:0010029 regulation of seed germination 生物过程
GO:0010086 embryonic root morphogenesis 生物过程
KEGG 基因交叉引用
ath:AT2G01830
ath:AT5G35750
dosa:Os03g0717700
mtr:11411168
osa:107275680
以下为同源蛋白关联的 KEGG 基因编号，不代表本基因已获得通路功能验证。
打开注释模块

基因表达

查看该基因在不同研究、组织与处理条件下的表达量。表达结果按研究与计量单位分别展示。

查看该基因的表达量
数据来源与对应关系说明

表达数据来自公开转录组研究；参考版本、样本信息和表达单位见查询结果。跨参考版本的对应关系不唯一时，不自动选择表达记录；缺失值不视为表达量为零。

亚细胞定位 Top 5

以下为计算预测或同源注释，不能替代定位实验。

内质网0.366
排名 1 · TkA05G251580 · TK1151
线粒体0.152
排名 2 · TkA05G251580 · TK1151
细胞质0.146
排名 3 · TkA05G251580 · TK1151
细胞核0.112
排名 4 · TkA05G251580 · TK1151
过氧化物酶体0.094
排名 5 · TkA05G251580 · TK1151

LocPro · 直接预测 · 计算预测，非定位实验结果

进入亚细胞定位查询

预测功能结构域

结构域结果来自 Pfam-A/HMMER；位置为对应蛋白序列上的氨基酸坐标。

PF02936COX418-92 aa
PF03924CHASE106-297 aa
PF00512HisKA358-375 aa
PF00512HisKA385-450 aa
PF02518HATPase_c497-565 aa
PF02518HATPase_c573-644 aa
PF24896Receiver_CRE1659-768 aa
PF00072Response_reg667-695 aa
基因 ID结构域编号结构域名称起始 aa终止 aaE 值评分
TkA05G251580PF02936COX418920.2612.0
TkA05G251580PF03924CHASE1062973.5e-37128.8
TkA05G251580PF00512HisKA3583755.4e-1968.7
TkA05G251580PF00512HisKA3854505.4e-1968.7
TkA05G251580PF02518HATPase_c4975652.6e-2486.5
TkA05G251580PF02518HATPase_c5736442.6e-2486.5
TkA05G251580PF24896Receiver_CRE16597683.2e-33115.5
TkA05G251580PF00072Response_reg6676959e-2278.1
TkA05G251580PF24896Receiver_CRE17939143.2e-33115.5
TkA05G251580PF00072Response_reg7969209e-2278.1
TkA05G251580PF03924CHASE8809203.5e-37128.8

拟南芥 / 水稻蛋白同源

仅展示拟南芥和水稻；Swiss-Prot 为人工审校条目，TrEMBL 为补充序列候选。同源相似性不等同于实验验证。

下载当前结果

蛋白物种描述一致性数据库置信等级
Q9C5U1拟南芥sp|Q9C5U1|AHK3_ARATH Histidine kinase 369.400%Swiss-Prot高置信
Q9C5U2拟南芥sp|Q9C5U2|AHK2_ARATH Histidine kinase 256.700%Swiss-Prot高置信
A2WYI4水稻sp|A2WYI4|OHK3_ORYSI Probable histidine kinase 363.400%Swiss-Prot高置信
A1A696水稻sp|A1A696|OHK3_ORYSJ Probable histidine kinase 363.300%Swiss-Prot高置信
A1A697水稻sp|A1A697|OHK5_ORYSJ Probable histidine kinase 556.100%Swiss-Prot高置信

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