LXL04_022485 | RubberDandelionOmics

基因概览

LXL04_022485

当前版本: OH-1004 染色体: Chr04 坐标: 151266952-151270896 链方向: + 类型: protein_coding

cDNA / CDS / 蛋白序列

可用序列下载 CDS FASTA 蛋白 FASTA cDNA FASTA

cDNA

2865 bp · LXL04_022485|LXL04_022485|OH1004|cDNA

ATGGGTTTAAAAATGCAAGCGAACGGGCACGGCCACCATCACTTGGTGGCGGTGAGTTTAAACGAACAGCAACTCGGTACAAAACGAAAGTACAGAACTTATtttccaagaacaaatcaagGAAAATACTTAGCATTATGGATAATTGCTTTTGGGTTTGCGGCGGTTTATGTTTATCGATGCATAGATGAAGGGCACCAAGAGAGAATTGAAGAAGGGTTAGTGAGTATGTGTGATCAGAGGGCCAGAATGTTGCAGGA...

CDS

下载 CDS FASTA

2865 bp · LXL04_022485|LXL04_022485|OH1004|CDS

ATGGGTTTAAAAATGCAAGCGAACGGGCACGGCCACCATCACTTGGTGGCGGTGAGTTTAAACGAACAGCAACTCGGTACAAAACGAAAGTACAGAACTTATTTTCCAAGAACAAATCAAGGAAAATACTTAGCATTATGGATAATTGCTTTTGGGTTTGCGGCGGTTTATGTTTATCGATGCATAGATGAAGGGCACCAAGAGAGAATTGAAGAAGGGTTAGTGAGTATGTGTGATCAGAGGGCCAGAATGTTGCAGGA...

蛋白

下载蛋白 FASTA

954 aa · LXL04_022485|LXL04_022485|OH1004|PROTEIN

MGLKMQANGHGHHHLVAVSLNEQQLGTKRKYRTYFPRTNQGKYLALWIIAFGFAAVYVYRCIDEGHQERIEEGLVSMCDQRARMLQDQFSVSVNHVHALAVLVSTFHYYKNPSVIDQETFAEYTARTAFERPLLSGVAYAQRVMNSEREEFESQHGGTIRTMANKEPSPHRDEYAPVIFAQETVSYLNLLDMMSGEEDRENILRARSTGKAVLTSPFKLLGSHHLGVVLTIPVYKSKLPPNASVRDRIEATAGYLGGAFD...

上下游序列下载

序列方向与下载说明

上游/下游最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

多版本 ID 对照

输入 ID	`LXL04_022485`
版本	OH-1004 / GCA_047496595.1_OSU_TarKok_2.0

查看完整 ID 对照表

SNP / Indel 变异与样本携带情况CRA009020 · OH-1004

展开后加载该基因的变异记录。

基因基本信息与功能注释

基因 ID LXL04_022485

位置 Chr04:151266952-151270896 (+)

描述 Similar to AHK4: Histidine kinase 4

拟南芥 / 水稻参考基因与文献

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拟南芥

参考基因 ID	可能功能	对应论文 / DOI
`At2g01830`	与细菌双组分调节剂相关的细胞分裂素受体。	The Arabidopsis sensor His-kinase, AHk4, can respond to cytokinins.2001 · DOI: 10.1093/pcp/pce037 Identification of CRE1 as a cytokinin receptor from Arabidopsis.2001 · DOI: 10.1038/35059117 The AHK4 gene involved in the cytokinin-signaling pathway as a direct receptor molecule in Arabidopsis thaliana.2001 · DOI: 10.1093/pcp/pce094 The Arabidopsis AHK4 histidine kinase is a cytokinin-binding receptor that transduces cytokinin signals across the membrane.2001 · DOI: 10.1093/pcp/pce127 Characterization of the ARR15 and ARR16 response regulators with special reference to the cytokinin signaling pathway mediated by the AHK4 histidine kinase in roots of Arabidopsis thaliana.2002 · DOI: 10.1093/pcp/pcf121 Mutations at CRE1 impair cytokinin-induced repression of phosphate starvation responses in Arabidopsis.2002 · DOI: 10.1046/j.1365-313x.2002.01431.x Interallelic complementation at the Arabidopsis CRE1 locus uncovers independent pathways for the proliferation of vascular initials and canonical cytokinin signalling.2004 · DOI: 10.1111/j.1365-313x.2004.02023.x A novel regulatory pathway of sulfate uptake in Arabidopsis roots: implication of CRE1/WOL/AHK4-mediated cytokinin-dependent regulation.2004 · DOI: 10.1111/j.1365-313x.2004.02079.x Histidine kinase homologs that act as cytokinin receptors possess overlapping functions in the regulation of shoot and root growth in Arabidopsis.2004 · DOI: 10.1105/tpc.021477 In planta functions of the Arabidopsis cytokinin receptor family.2004 · DOI: 10.1073/pnas.0402887101 Two cytokinin receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, differ in their ligand specificity in a bacterial assay.2004 · DOI: 10.1093/pcp/pch132 Topolins and hydroxylated thidiazuron derivatives are substrates of cytokinin O-glucosyltransferase with position specificity related to receptor recognition.2005 · DOI: 10.1104/pp.104.057174 Interaction between phosphate-starvation, sugar, and cytokinin signaling in Arabidopsis and the roles of cytokinin receptors CRE1/AHK4 and AHK3.2005 · DOI: 10.1104/pp.105.060517 A live cell hormone-binding assay on transgenic bacteria expressing a eukaryotic receptor protein.2005 · DOI: 10.1016/j.ab.2005.09.012 Cytokinin receptors are required for normal development of auxin-transporting vascular tissues in the hypocotyl but not in adventitious roots.2006 · DOI: 10.1093/pcp/pci240 Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism.2006 · DOI: 10.1105/tpc.105.037796 Cytokinins regulate a bidirectional phosphorelay network in Arabidopsis.2006 · DOI: 10.1016/j.cub.2006.04.030 Biochemical characteristics and ligand-binding properties of Arabidopsis cytokinin receptor AHK3 compared to CRE1/AHK4 as revealed by a direct binding assay.2006 · DOI: 10.1093/jxb/erl179 The floral volatile, methyl benzoate, from snapdragon (Antirrhinum majus) triggers phytotoxic effects in Arabidopsis thaliana.2007 · DOI: 10.1007/s00425-006-0464-0 Identification of amino acid substitutions that render the Arabidopsis cytokinin receptor histidine kinase AHK4 constitutively active.2007 · DOI: 10.1093/pcp/pcm145 Cytokinin receptors are involved in alkamide regulation of root and shoot development in Arabidopsis.2007 · DOI: 10.1104/pp.107.107953 Functional analysis of AHK1/ATHK1 and cytokinin receptor histidine kinases in response to abscisic acid, drought, and salt stress in Arabidopsis.2007 · DOI: 10.1073/pnas.0706547105 Cytokinins negatively regulate the root iron uptake machinery in Arabidopsis through a growth-dependent pathway.2008 · DOI: 10.1111/j.1365-313x.2008.03502.x Mechanism-based inhibitors of cytokinin oxidase/dehydrogenase attack FAD cofactor.2008 · DOI: 10.1016/j.jmb.2008.05.044 The role of auxins and cytokinins in the mutualistic interaction between Arabidopsis and Piriformospora indica.2008 · DOI: 10.1094/mpmi-21-10-1371 The purine derivative PI-55 blocks cytokinin action via receptor inhibition.2009 · DOI: 10.1111/j.1742-4658.2008.06777.x
`At5g35750`	与细菌双组分调节剂相关的细胞分裂素受体。	Histidine kinase homologs that act as cytokinin receptors possess overlapping functions in the regulation of shoot and root growth in Arabidopsis.2004 · DOI: 10.1105/tpc.021477 In planta functions of the Arabidopsis cytokinin receptor family.2004 · DOI: 10.1073/pnas.0402887101 Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism.2006 · DOI: 10.1105/tpc.105.037796 Cytokinins regulate a bidirectional phosphorelay network in Arabidopsis.2006 · DOI: 10.1016/j.cub.2006.04.030 Identification of amino acid substitutions that render the Arabidopsis cytokinin receptor histidine kinase AHK4 constitutively active.2007 · DOI: 10.1093/pcp/pcm145 Cytokinin receptors are involved in alkamide regulation of root and shoot development in Arabidopsis.2007 · DOI: 10.1104/pp.107.107953 Functional analysis of AHK1/ATHK1 and cytokinin receptor histidine kinases in response to abscisic acid, drought, and salt stress in Arabidopsis.2007 · DOI: 10.1073/pnas.0706547105 The role of auxins and cytokinins in the mutualistic interaction between Arabidopsis and Piriformospora indica.2008 · DOI: 10.1094/mpmi-21-10-1371 The histidine kinases CYTOKININ-INDEPENDENT1 and ARABIDOPSIS HISTIDINE KINASE2 and 3 regulate vascular tissue development in Arabidopsis shoots.2009 · DOI: 10.1105/tpc.109.066696 Cytokinin overproduction-caused alteration of flower development is partially mediated by CUC2 and CUC3 in Arabidopsis.2010 · DOI: 10.1016/j.gene.2009.11.003 A subset of cytokinin two-component signaling system plays a role in cold temperature stress response in Arabidopsis.2010 · DOI: 10.1074/jbc.m109.096644

水稻

参考基因 ID	可能功能	对应论文 / DOI
`Os03g0717700`	与细菌双组分调控器相关的细胞分裂素受体。	暂无已核实直接文献
`Os02g0738400`	与细菌双组分调控器相关的细胞分裂素受体。	暂无已核实直接文献

功能注释来源

查看注释来源

功能注释来源：OH1004 · LXL04_022485 · GCA_047496595.1_OSU_TarKok_2.0。

GO 注释（OH1004 来源）

GO:0000160 phosphorelay signal transduction system 生物过程

GO:0006468 protein phosphorylation 生物过程

GO:0006970 response to osmotic stress 生物过程

GO:0007231 osmosensory signaling pathway 生物过程

GO:0009414 response to water deprivation 生物过程

GO:0009636 response to toxic substance 生物过程

GO:0009651 response to salt stress 生物过程

GO:0009736 cytokinin-activated signaling pathway 生物过程

GO:0009737 response to abscisic acid 生物过程

GO:0009909 regulation of flower development 生物过程

GO:0010029 regulation of seed germination 生物过程

GO:0010086 embryonic root morphogenesis 生物过程

KEGG 基因交叉引用

ath:AT2G01830

ath:AT5G35750

dosa:Os03g0717700

mtr:11411168

osa:107275680

以下为同源蛋白关联的 KEGG 基因编号，不代表本基因已获得通路功能验证。

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基因表达

查看该基因在不同研究、组织与处理条件下的表达量。表达结果按研究与计量单位分别展示。

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数据来源与对应关系说明

表达数据来自公开转录组研究；参考版本、样本信息和表达单位见查询结果。跨参考版本的对应关系不唯一时，不自动选择表达记录；缺失值不视为表达量为零。

亚细胞定位 Top 5

以下为计算预测或同源注释，不能替代定位实验。

内质网0.465

排名 1 · LXL04_022485 · OH-1004

高尔基体0.166

排名 2 · LXL04_022485 · OH-1004

细胞质0.143

排名 3 · LXL04_022485 · OH-1004

细胞膜0.142

排名 4 · LXL04_022485 · OH-1004

细胞核0.112

排名 5 · LXL04_022485 · OH-1004

LocPro · 直接预测 · 计算预测，非定位实验结果

进入亚细胞定位查询

预测功能结构域

结构域结果来自 Pfam-A/HMMER；位置为对应蛋白序列上的氨基酸坐标。

PF03924.20CHASE115-295 aa

PF00512.32HisKA385-450 aa

PF02518.32HATPase_c588-659 aa

PF24896.2Receiver_CRE1682-795 aa

PF00072.31Response_reg822-942 aa

基因 ID	结构域编号	结构域名称	起始 aa	终止 aa	E 值	评分
LXL04_022485	`PF03924.20`	CHASE	115	295	8.1e-38	130.8
LXL04_022485	`PF00512.32`	HisKA	385	450	2.1e-20	73.3
LXL04_022485	`PF02518.32`	HATPase_c	588	659	7.3e-23	81.8
LXL04_022485	`PF24896.2`	Receiver_CRE1	682	795	1e-38	133.3
LXL04_022485	`PF00072.31`	Response_reg	822	942	1.7e-23	83.6

拟南芥 / 水稻蛋白同源

仅展示拟南芥和水稻；Swiss-Prot 为人工审校条目，TrEMBL 为补充序列候选。同源相似性不等同于实验验证。

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蛋白	物种	描述	一致性	数据库	置信等级
`Q9C5U0`	拟南芥	Histidine kinase 4	68.937%	Swiss-Prot	强数据库同源证据
`Q9C5U2`	拟南芥	Histidine kinase 2	54.425%	Swiss-Prot	强数据库同源证据
`A1A698`	水稻	Probable histidine kinase 4	60.774%	Swiss-Prot	强数据库同源证据
`A1A699`	水稻	Probable histidine kinase 6	60.645%	Swiss-Prot	强数据库同源证据

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