TkA04G019000 | RubberDandelionOmics

Gene overview

TkA04G019000

Reference: TK1151 Chr: Chr04 Coordinates: 4766276-4767304 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

762 bp · TkA04G019000|TK1151|cDNA

ATGGCGGACATTAGGGTGTTGTACAACGAGTTCTTCAACATGCCGATTGAGGACAAGTTAAGCGTTTACTCTGAGAATTTCGGTAAAGGGTGTTCGCTTTATACGAGCGGTTTGAATAAGACAAAAGAAGATGTTCGTTTATGGAAAGATACTTTGAAGCACGAGTGTCATCCTTTGGACGAACATAGTCCATCGTGGCCAGAAAAACCAGCCAGATATCGGGAGGAAGTGGGAAAATACACGGTTGAAGTACGTAAAAT...

CDS

Download CDS FASTA

762 bp · TkA04G019000|TK1151|CDS

ATGGCGGACATTAGGGTGTTGTACAACGAGTTCTTCAACATGCCGATTGAGGACAAGTTAAGCGTTTACTCTGAGAATTTCGGTAAAGGGTGTTCGCTTTATACGAGCGGTTTGAATAAGACAAAAGAAGATGTTCGTTTATGGAAAGATACTTTGAAGCACGAGTGTCATCCTTTGGACGAACATAGTCCATCGTGGCCAGAAAAACCAGCCAGATATCGGGAGGAAGTGGGAAAATACACGGTTGAAGTACGTAAAAT...

Protein

Download Protein FASTA

253 aa · TkA04G019000|TK1151|PROTEIN

MADIRVLYNEFFNMPIEDKLSVYSENFGKGCSLYTSGLNKTKEDVRLWKDTLKHECHPLDEHSPSWPEKPARYREEVGKYTVEVRKMGFKILDMIGEGLGLSEGYFVEVIQEQLMAINHYPPCPDPSLVMGIVAHTDPNLITFLQQDQYGLQIQNDRIWMGIDPNPNAFVVNLGHQFKIISNEKLKSAEHRGVLNSTASRTSIVTFFVPDLHDVFRTWPSSTNHFLVMEHRSILIGSKYNLFFANHVKYKIRS

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA04G019000`
TK1151 ID	TkA04G019000
OH-1004 ID	LXL04_036879
Relationship / confidence	Sequence Supported Annotation Or Model Conflict / Review
Protein identity (%)	100.000
Protein coverage (%)	TK1151 100.000 / OH-1004 28.914 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

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Basic Information and Functional Annotation

Gene ID TkA04G019000

Location Chr04:4766276-4767304 (+)

Description Similar to H6H: Hyoscyamine 6-dioxygenase

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At5g24530`	Converts salicylic acid (SA) to 2,3-dihydroxybenzoic acid (2,3-DHBA) (By similarity).	Identification of arabidopsis loci required for susceptibility to the downy mildew pathogen Hyaloperonospora parasitica.2005 · DOI: 10.1094/mpmi-18-0583 Arabidopsis DMR6 encodes a putative 2OG-Fe(II) oxygenase that is defense-associated but required for susceptibility to downy mildew.2008 · DOI: 10.1111/j.1365-313x.2008.03427.x DOWNY MILDEW RESISTANT 6 and DMR6-LIKE OXYGENASE 1 are partially redundant but distinct suppressors of immunity in Arabidopsis.2015 · DOI: 10.1111/tpj.12719
`At4g10500`	Converts salicylic acid (SA) to both 2,3-dihydroxybenzoic acid (2,3-DHBA) and 2,5-DHBA in vitro but only 2,3-DHBA in vivo.	DOWNY MILDEW RESISTANT 6 and DMR6-LIKE OXYGENASE 1 are partially redundant but distinct suppressors of immunity in Arabidopsis.2015 · DOI: 10.1111/tpj.12719
`At4g10490`	Converts salicylic acid (SA) to 2,3-dihydroxybenzoic acid (2,3-DHBA) (By similarity).	DOWNY MILDEW RESISTANT 6 and DMR6-LIKE OXYGENASE 1 are partially redundant but distinct suppressors of immunity in Arabidopsis.2015 · DOI: 10.1111/tpj.12719

Rice

Reference gene ID	Possible function	Papers / DOI
`Os10g0536400`	Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants.	Flavanone 3beta-hydroxylases from rice: key enzymes for favonol and anthocyanin biosynthesis.2008 · DOI: 10.1016/s1016-8478(23)17587-x

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_036879 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0002238 response to molecule of fungal origin Biological Process

GO:0009805 coumarin biosynthetic process Biological Process

GO:0031418 L-ascorbic acid binding Molecular Function

GO:0046872 metal ion binding Molecular Function

GO:0047998 hyoscyamine (6S)-dioxygenase activity Molecular Function

KEGG gene cross-reference

ag:BAA05630

ag:BAA78340

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.742

Rank 1 · TkA04G019000 · TK1151

Nucleus0.238

Rank 2 · TkA04G019000 · TK1151

Peroxisome0.073

Rank 3 · TkA04G019000 · TK1151

Endoplasmic reticulum0.063

Rank 4 · TkA04G019000 · TK1151

Mitochondrion0.054

Rank 5 · TkA04G019000 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF14226DIOX_N3-68 aa

PF031712OG-FeII_Oxy112-208 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA04G019000	`PF14226`	DIOX_N	3	68	4.6e-05	24.8
TkA04G019000	`PF03171`	2OG-FeII_Oxy	112	208	1.3e-27	96.8

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

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Protein	Organism	Description	Identity	Database	Confidence
`Q9FLV0`	Arabidopsis thaliana	sp\|Q9FLV0\|DMR6_ARATH Protein DOWNY MILDEW RESISTANCE 6	44.600%	Swiss-Prot	Medium
`Q9ZSA8`	Arabidopsis thaliana	sp\|Q9ZSA8\|DLO1_ARATH Protein DMR6-LIKE OXYGENASE 1	37.200%	Swiss-Prot	Medium
`Q9ZSA7`	Arabidopsis thaliana	sp\|Q9ZSA7\|DLO2_ARATH Protein DMR6-LIKE OXYGENASE 2	42.400%	Swiss-Prot	Medium
`Q8W2X5`	Oryza sativa subsp. japonica	sp\|Q8W2X5\|FL3H2_ORYSJ Flavanone 3-dioxygenase 2	42.700%	Swiss-Prot	Medium

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