Gene Card
Gene overview
cDNA / CDS / Protein Sequences
1889 bp · TkA02G017250|TK1151|cDNA
GGAGTGGTAAATATCAAGATGGTATGGTGTGTGTAATGTGGTGTGACATGACACCCACCATATTTCTTTGGTATTATTAATGTTCTATTTGGTTTTGCAAAACCCCTTTCATTCTATCTCTCAGAATTGCGTGTGCCTTAGACGAGGGAAATTTCAAGAAAATGTCACTGGGGTATGCAGAGAAGCTCTCCTATAAAGAAGACGTTGGGGATGTCGGAATGTCCGAGATGTTCGACTCGCCAGATGATTTGCAACAAAAA...
1416 bp · TkA02G017250|TK1151|CDS
ATGTCACTGGGGTATGCAGAGAAGCTCTCCTATAAAGAAGACGTTGGGGATGTCGGAATGTCCGAGATGTTCGACTCGCCAGATGATTTGCAACAAAAAATTAACCAGCTCGCAAATATGATTAAAAAGAGTAAGCATCTAGTGGCATTTACAGGTGCAGGAATCTCAACTTCTTGTGGGATACCTGATTTTCGAGGCCCAAAAGGCGTTTGGACTCTTCAGCGTGAGGGCAAAGGTATTCCAGAAGCATCCTTGCCATT...
Protein
Download Protein FASTA471 aa · TkA02G017250|TK1151|PROTEIN
MSLGYAEKLSYKEDVGDVGMSEMFDSPDDLQQKINQLANMIKKSKHLVAFTGAGISTSCGIPDFRGPKGVWTLQREGKGIPEASLPFHRASPSLTHMALVGLEKAGILKFVISQNVDSLHLRSGIPRNKLSELHGNSFREVCPSCGTEYLRDFEVETIGFKDTSRRCSDAKCGAKLKDSVLDWEDELPPTETNAAEKHCRMADIVLCLGTSLQITPACNLPLKSVRKGGKMVIVNLQETPKDKKASLVIRGFVDKVMAGV...
Flanking Sequence Download
Sequence orientation and download details
Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.
ID Mapping
| Input ID | TkA02G017250 |
|---|---|
| TK1151 ID | TkA02G017250 |
| OH-1004 ID | LXL04_031047 |
| Relationship / confidence | Rbh Below Probable Coverage Or Synteny Threshold / Review |
| Protein identity (%) | 62.400 |
| Protein coverage (%) | TK1151 92.994 / OH-1004 93.590Coverage and evidenceCoverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation. |
| Source version | TK1151 / GWHBCHF00000000 |
SNP / Indel variants and carrier samplesCRA009020 · TK1151
Expand to load variant records for this gene.
Basic Information and Functional Annotation
| Gene ID | TkA02G017250 | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Location | Chr02:4052484-4055970 (-) | |||||||||||||||
| Description | Similar to SRT1: NAD-dependent protein deacetylase SRT1 | |||||||||||||||
| Arabidopsis / Rice Reference Genes and Papers |
Download references for this gene Arabidopsis
Rice
| |||||||||||||||
| Functional annotation source | View annotation sourcesFunctional annotation source: OH1004 · | |||||||||||||||
| GO annotations (OH1004 source) | GO:0000122 negative regulation of transcription by RNA polymerase II Biological Process GO:0006302 double-strand break repair Biological Process GO:0006606 protein import into nucleus Biological Process GO:0008340 determination of adult lifespan Biological Process GO:0009411 response to UV Biological Process GO:0009873 ethylene-activated signaling pathway Biological Process GO:0010526 transposable element silencing Biological Process GO:0010569 regulation of double-strand break repair via homologous recombination Biological Process GO:0019216 regulation of lipid metabolic process Biological Process GO:0031508 pericentric heterochromatin formation Biological Process GO:0031509 subtelomeric heterochromatin formation Biological Process GO:0031648 protein destabilization Biological Process | |||||||||||||||
| KEGG gene cross-reference | ath:AT5G55760 dosa:Os04g0271000 osa:4335342 These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene. |
Gene expression
View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.
Data sources and gene correspondence
Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.
Subcellular Localization Top 5
Computational predictions or homology annotations below do not replace localization experiments.
LocPro · Direct prediction · Computational prediction, not experimental localization
Predicted Functional Domains
Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.
PF00205TPP_enzyme_M34-58 aaPF02146SIR252-74 aaPF02146SIR288-216 aaPF26788DUF8260128-148 aaPF07282Cas12f1-like_TNB141-153 aaPF13240Zn_Ribbon_1142-149 aaPF07282Cas12f1-like_TNB154-176 aaPF13240Zn_Ribbon_1171-178 aa| Gene ID | Domain ID | Domain Name | Start aa | End aa | E-value | Score |
|---|---|---|---|---|---|---|
| TkA02G017250 | PF00205 | TPP_enzyme_M | 34 | 58 | 0.01 | 16.3 |
| TkA02G017250 | PF02146 | SIR2 | 52 | 74 | 1e-26 | 94.7 |
| TkA02G017250 | PF02146 | SIR2 | 88 | 216 | 1e-26 | 94.7 |
| TkA02G017250 | PF26788 | DUF8260 | 128 | 148 | 0.16 | 12.7 |
| TkA02G017250 | PF07282 | Cas12f1-like_TNB | 141 | 153 | 0.18 | 12.7 |
| TkA02G017250 | PF13240 | Zn_Ribbon_1 | 142 | 149 | 0.14 | 12.6 |
| TkA02G017250 | PF07282 | Cas12f1-like_TNB | 154 | 176 | 0.18 | 12.7 |
| TkA02G017250 | PF13240 | Zn_Ribbon_1 | 171 | 178 | 0.14 | 12.6 |
| TkA02G017250 | PF26788 | DUF8260 | 171 | 194 | 0.16 | 12.7 |
| TkA02G017250 | PF00205 | TPP_enzyme_M | 190 | 242 | 0.01 | 16.3 |
| TkA02G017250 | PF13240 | Zn_Ribbon_1 | 396 | 401 | 0.14 | 12.6 |
Arabidopsis / Rice Protein Homology
Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.
| Protein | Organism | Description | Identity | Database | Confidence |
|---|---|---|---|---|---|
Q9FE17 | Arabidopsis thaliana | sp|Q9FE17|SIR1_ARATH NAD-dependent protein deacetylase SRT1 | 63.300% | Swiss-Prot | High |
B8ARK7 | Oryza sativa subsp. indica | sp|B8ARK7|SRT1_ORYSI NAD-dependent protein deacetylase SRT1 | 62.300% | Swiss-Prot | High |
Q7XWV4 | Oryza sativa subsp. japonica | sp|Q7XWV4|SRT1_ORYSJ NAD-dependent protein deacetylase SRT1 | 62.300% | Swiss-Prot | High |