Gene Card
Gene overview
cDNA / CDS / Protein Sequences
2645 bp · TkA01G628460|TK1151|cDNA
CATTGGAACACGATGGAATCCATGGAAGCAACGAGGACGATAACGGAAATGCTTCTCACTTATTTCCCTTTCGTTTAAACAAACCAAGATTTCGAGTTTTCTAGGTTTCAATTCATGTCCAGACCATCCAGACAATGATCATCACACGCATATCACGATATCTCTCCCGTTCCTCTCACTCTACGTTCCAACGAAATGTGAGGGGAGTGATTTCAAGGGAATCATCAACAAATGCGAGCATCGCACGCTTAGAGGGCGGA...
2292 bp · TkA01G628460|TK1151|CDS
ATGATCATCACACGCATATCACGATATCTCTCCCGTTCCTCTCACTCTACGTTCCAACGAAATGTGAGGGGAGTGATTTCAAGGGAATCATCAACAAATGCGAGCATCGCACGCTTAGAGGGCGGAGCAGGGCTCGTGAGGACCTACTTAACCTCAGTTTGTGCTAAGGGGCCGATTATTAACCCTAAAAATCTAGCAAAAAACCTAGGGCTACGAAGGCTGTTCTGCAGCGAGGCACCAAAGAGAAAACACTATGAAAA...
Protein
Download Protein FASTA763 aa · TkA01G628460|TK1151|PROTEIN
MIITRISRYLSRSSHSTFQRNVRGVISRESSTNASIARLEGGAGLVRTYLTSVCAKGPIINPKNLAKNLGLRRLFCSEAPKRKHYENYYPKGKREVPKGEGQKSGSKGDSGKNDNRENLMKQYQTLISPLMFFAFVLSSIFLTPQEQKQISFQEFKNKLLEPGLVDHIVVTNKSVAKVYVKPSLPHRIQVNEEPVQGGNVGSRGEVSHYEYYFNIGSVETFEEKLEEAQEALGIDPHNYVPVTYSSETNWGQELIRLTPT...
Flanking Sequence Download
Sequence orientation and download details
Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.
ID Mapping
| Input ID | TkA01G628460 |
|---|---|
| TK1151 ID | TkA01G628460 |
| OH-1004 ID | LXL04_000189 |
| Relationship / confidence | Rbh High Identity Coverage Synteny / Strict |
| Protein identity (%) | 95.200 |
| Protein coverage (%) | TK1151 100.000 / OH-1004 100.000Coverage and evidenceCoverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation. |
| Source version | TK1151 / GWHBCHF00000000 |
SNP / Indel variants and carrier samplesCRA009020 · TK1151
Expand to load variant records for this gene.
Basic Information and Functional Annotation
| Gene ID | TkA01G628460 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Location | Chr01:158913639-158917989 (+) | ||||||||||||||||||
| Description | Similar to FTSH8: ATP-dependent zinc metalloprotease FTSH 8, mitochondrial | ||||||||||||||||||
| Arabidopsis / Rice Reference Genes and Papers |
Download references for this gene Arabidopsis
Rice
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| Functional annotation source | View annotation sourcesFunctional annotation source: OH1004 · | ||||||||||||||||||
| GO annotations (OH1004 source) | GO:0006508 proteolysis Biological Process GO:0016485 protein processing Biological Process GO:0016540 protein autoprocessing Biological Process GO:0030163 protein catabolic process Biological Process GO:0033619 membrane protein proteolysis Biological Process GO:0034982 mitochondrial protein processing Biological Process GO:0036444 calcium import into the mitochondrion Biological Process GO:0051560 mitochondrial calcium ion homeostasis Biological Process GO:0051604 protein maturation Biological Process GO:0072753 cellular response to glutathione Biological Process GO:0110097 regulation of calcium import into the mitochondrion Biological Process GO:0141164 mitochondrial protein quality control Biological Process | ||||||||||||||||||
| KEGG gene cross-reference | ath:AT1G07510 ath:AT2G29080 dosa:Os01g0842600 dosa:Os05g0458400 hsa:10939 These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene. |
Gene expression
View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.
Data sources and gene correspondence
Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.
Subcellular Localization Top 5
Computational predictions or homology annotations below do not replace localization experiments.
LocPro · Direct prediction · Computational prediction, not experimental localization
Predicted Functional Domains
Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.
PF06480FtsH_ext131-238 aaPF00005ABC_tran166-242 aaPF08298AAA_PrkA294-381 aaPF13191AAA_16343-364 aaPF06068TIP49344-380 aaPF05496RuvB_N346-414 aaPF01078Mg_chelatase346-362 aaPF00004AAA347-479 aa| Gene ID | Domain ID | Domain Name | Start aa | End aa | E-value | Score |
|---|---|---|---|---|---|---|
| TkA01G628460 | PF06480 | FtsH_ext | 131 | 238 | 3.6e-10 | 40.7 |
| TkA01G628460 | PF00005 | ABC_tran | 166 | 242 | 0.2 | 13.0 |
| TkA01G628460 | PF08298 | AAA_PrkA | 294 | 381 | 0.16 | 11.7 |
| TkA01G628460 | PF13191 | AAA_16 | 343 | 364 | 0.038 | 15.2 |
| TkA01G628460 | PF06068 | TIP49 | 344 | 380 | 0.0027 | 17.6 |
| TkA01G628460 | PF05496 | RuvB_N | 346 | 414 | 0.0062 | 17.0 |
| TkA01G628460 | PF01078 | Mg_chelatase | 346 | 362 | 0.093 | 12.8 |
| TkA01G628460 | PF00004 | AAA | 347 | 479 | 9.6e-43 | 146.5 |
| TkA01G628460 | PF07728 | AAA_5 | 347 | 415 | 0.0004 | 21.1 |
| TkA01G628460 | PF13401 | AAA_22 | 347 | 375 | 0.00076 | 20.5 |
| TkA01G628460 | PF07724 | AAA_2 | 347 | 416 | 0.011 | 16.5 |
| TkA01G628460 | PF13173 | AAA_14 | 347 | 414 | 0.045 | 14.5 |
| TkA01G628460 | PF13671 | AAA_33 | 347 | 385 | 0.14 | 13.2 |
| TkA01G628460 | PF00005 | ABC_tran | 347 | 368 | 0.2 | 13.0 |
| TkA01G628460 | PF13207 | AAA_17 | 349 | 387 | 0.14 | 13.1 |
| TkA01G628460 | PF13191 | AAA_16 | 390 | 414 | 0.038 | 15.2 |
Arabidopsis / Rice Protein Homology
Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.
| Protein | Organism | Description | Identity | Database | Confidence |
|---|---|---|---|---|---|
Q8VZI8 | Arabidopsis thaliana | sp|Q8VZI8|FTSHA_ARATH ATP-dependent zinc metalloprotease FTSH 10, mitochondrial | 70.100% | Swiss-Prot | High |
Q84WU8 | Arabidopsis thaliana | sp|Q84WU8|FTSH3_ARATH ATP-dependent zinc metalloprotease FTSH 3, mitochondrial | 72.400% | Swiss-Prot | High |
Q0DHL4 | Oryza sativa subsp. japonica | sp|Q0DHL4|FTSH8_ORYSJ ATP-dependent zinc metalloprotease FTSH 8, mitochondrial | 76.100% | Swiss-Prot | High |
Q8S2A7 | Oryza sativa subsp. japonica | sp|Q8S2A7|FTSH3_ORYSJ ATP-dependent zinc metalloprotease FTSH 3, mitochondrial | 69.800% | Swiss-Prot | High |