TkA08G138010 | RubberDandelionOmics

Gene overview

TkA08G138010

Reference: TK1151 Chr: Chr08 Coordinates: 35901741-35926243 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

1317 bp · TkA08G138010|TK1151|cDNA

TTAAAACTTAAAAAGTAAATTTTCATATATCGCTATATTAAAAGTACTAGTTTGCAGTTATAAAATGTGATACAAGTTCCTGGTCTCCTATATCTTTTGACCATATCTTCCGCATGAGGCACTGATTGGTACGTAATTTGCTTCTAGATTAGCTTTGAAAATCCTCTCGCCCCTCATAATCTAAAAACCACGACGACGACCTTTCAGTATACCGACGGCAGTAAAAAGCGATGGATCAGATTCACAGATTCCTAAACATT...

CDS

Download CDS FASTA

933 bp · TkA08G138010|TK1151|CDS

ATGGATCAGATTCACAGATTCCTAAACATTCTTTCTATTATTCTATCGGTCATCTCATGCATCTTCCTCTTGCCGGCAATTTCATTGTTCCGCGTCTTGAGGTTCTGTATCAGATCTATATACCGAGAAAAACTCGCCGGAAAAGTGGTGCTTATTACCGGTGCTTCATCCGGTATCGGCGAGCATCTGGCGTATGAGTATGCGAAACATGGAGCGAACTTAGCGTTGGTTGCGAGAAGGGAGGAGCTGCTTGCGAGGGT...

Protein

Download Protein FASTA

310 aa · TkA08G138010|TK1151|PROTEIN

MDQIHRFLNILSIILSVISCIFLLPAISLFRVLRFCIRSIYREKLAGKVVLITGASSGIGEHLAYEYAKHGANLALVARREELLARVAGKAKKLGAPEAIVIKADVTKLHDCKRFVDVTVNHFGKLDCLINNAGIAKPGLFEDQRCITDYASTMDVNFWGSVNATHYALPHLRKSTGRIIVVGSTGGWFNTPRISLYNASKVAQQSFFETLRIELAPDIGITMVTLGTVTTPLANDELLTQASIKWVPMYSVEDCAKAIV...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA08G138010`
TK1151 ID	TkA08G138010
OH-1004 ID	LXL04_031954
Relationship / confidence	Rbh Below Probable Coverage Or Synteny Threshold / Review
Protein identity (%)	92.500
Protein coverage (%)	TK1151 95.161 / OH-1004 39.195 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA08G138010

Location Chr08:35901741-35926243 (+)

Description Similar to SOP2: 11-beta-hydroxysteroid dehydrogenase A

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At5g50590`	11-beta-hydroxysteroid dehydrogenase-like 4A.	No verified direct reference in this release
`At5g50690`	11-beta-hydroxysteroid dehydrogenase-like 4B.	No verified direct reference in this release
`At3g47350`	11-beta-hydroxysteroid dehydrogenase-like 2.	No verified direct reference in this release
`At5g50600`	Catalyzes 11-beta, 17-beta-hydroxysteroid and reduces 17- beta-ketosteroids.	At5g50600 encodes a member of the short-chain dehydrogenase reductase superfamily with 11beta- and 17beta-hydroxysteroid dehydrogenase activities associated with Arabidopsis thaliana seed oil bodies.2007 · DOI: 10.1016/j.biochi.2006.09.013 A putative hydroxysteroid dehydrogenase involved in regulating plant growth and development.2007 · DOI: 10.1104/pp.107.100560 Regulation of HSD1 in seeds of Arabidopsis thaliana.2009 · DOI: 10.1093/pcp/pcp092
`At3g47360`	11-beta-hydroxysteroid dehydrogenase-like 3.	No verified direct reference in this release

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_031954 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0006694 steroid biosynthetic process Biological Process

GO:0008202 steroid metabolic process Biological Process

GO:0005576 extracellular region Cellular Component

GO:0005811 lipid droplet Cellular Component

GO:0005829 cytosol Cellular Component

GO:0016020 membrane Cellular Component

GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity Molecular Function

GO:0016491 oxidoreductase activity Molecular Function

GO:0070523 11-beta-hydroxysteroid dehydrogenase (NAD+) activity Molecular Function

GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity Molecular Function

GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity Molecular Function

KEGG gene cross-reference

ath:AT5G50590

ath:AT5G50690

sind:105158152

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.574

Rank 1 · TkA08G138010 · TK1151

Cytoplasm0.156

Rank 2 · TkA08G138010 · TK1151

Cell membrane0.114

Rank 3 · TkA08G138010 · TK1151

Golgi apparatus0.106

Rank 4 · TkA08G138010 · TK1151

Mitochondrion0.103

Rank 5 · TkA08G138010 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF00106adh_short48-236 aa

PF08659KR50-214 aa

PF01370Epimerase50-184 aa

PF13561adh_short_C254-245 aa

PF22705C2-set_3103-134 aa

PF22705C2-set_3174-210 aa

PF01370Epimerase251-264 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA08G138010	`PF00106`	adh_short	48	236	1e-46	159.6
TkA08G138010	`PF08659`	KR	50	214	2.1e-09	38.3
TkA08G138010	`PF01370`	Epimerase	50	184	0.00015	22.0
TkA08G138010	`PF13561`	adh_short_C2	54	245	6e-32	111.8
TkA08G138010	`PF22705`	C2-set_3	103	134	0.14	12.8
TkA08G138010	`PF22705`	C2-set_3	174	210	0.14	12.8
TkA08G138010	`PF01370`	Epimerase	251	264	0.00015	22.0

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`P0DKC7`	Arabidopsis thaliana	sp\|P0DKC7\|HSD4A_ARATH 11-beta-hydroxysteroid dehydrogenase-like 4A	47.000%	Swiss-Prot	Medium
`Q9LUF2`	Arabidopsis thaliana	sp\|Q9LUF2\|HSD4B_ARATH 11-beta-hydroxysteroid dehydrogenase-like 4B	47.000%	Swiss-Prot	Medium
`Q9STY8`	Arabidopsis thaliana	sp\|Q9STY8\|HSD2_ARATH 11-beta-hydroxysteroid dehydrogenase-like 2	45.700%	Swiss-Prot	Medium
`P0DKC5`	Arabidopsis thaliana	sp\|P0DKC5\|HSD1A_ARATH 11-beta-hydroxysteroid dehydrogenase 1A	44.400%	Swiss-Prot	Medium
`Q9STY7`	Arabidopsis thaliana	sp\|Q9STY7\|HSD3_ARATH 11-beta-hydroxysteroid dehydrogenase-like 3	45.700%	Swiss-Prot	Medium

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