Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 8 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G396140
TK1151: TkA01G396140
OH-1004: LXL04_003084
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:66921183-66923389
+
go:0006970 response to osmotic stress biological_process
TkA01G359230
TK1151: TkA01G359230;TkA04G017170;TkA07G130450;TkA08G024430
OH-1004: LXL04_003442
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:79178967-79181472
+
go:0006970 response to osmotic stress biological_process
LXL04_003793
TK1151: -
OH-1004: LXL04_003793
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtCoexpression CM104799.1:102729078-102731464
-
go:0048527 lateral root development biological_process
TkA01G210250
TK1151: TkA01G210250
OH-1004: LXL04_004035
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:122730028-122733983
-
go:0010494 cytoplasmic stress granule cellular_component
LXL04_004037
TK1151: -
OH-1004: LXL04_004037
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:122743952-122744289
-
go:0010494 cytoplasmic stress granule cellular_component
LXL04_004043
TK1151: -
OH-1004: LXL04_004043
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:123221404-123222267
+
go:0006970 response to osmotic stress biological_process
TkA01G004390
TK1151: TkA01G004390;TkA01G132850
OH-1004: LXL04_004575
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:140916871-140919628
+
go:0006979 response to oxidative stress biological_process
TkA01G132810
TK1151: TkA01G132810
OH-1004: LXL04_004576
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:140934609-140935574
+
go:0006950 response to stress biological_process
TkA01G121250
TK1151: TkA01G121250
OH-1004: LXL04_004704
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPI CM104799.1:144024827-144026223
+
go:0006950 response to stress biological_process
TkA01G120640
TK1151: TkA01G120640
OH-1004: LXL04_004705
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:144124256-144125750
+
go:0006950 response to stress biological_process

TkA01G396140

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G396140
LocationCM104799.1:66921183-66923389 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G359230

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G359230;TkA04G017170;TkA07G130450;TkA08G024430
LocationCM104799.1:79178967-79181472 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

LXL04_003793

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104799.1:102729078-102731464 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0048527 lateral root development biological_process

TkA01G210250

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G210250
LocationCM104799.1:122730028-122733983 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

LXL04_004037

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104799.1:122743952-122744289 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

LXL04_004043

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104799.1:123221404-123222267 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G004390

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G004390;TkA01G132850
LocationCM104799.1:140916871-140919628 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA01G132810

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G132810
LocationCM104799.1:140934609-140935574 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006950 response to stress biological_process

TkA01G121250

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G121250
LocationCM104799.1:144024827-144026223 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0006950 response to stress biological_process

TkA01G120640

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G120640
LocationCM104799.1:144124256-144125750 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.