Para rubber tree · HRBP
Sequence IDLC057267
StepCPT/CPTL branch · CPTL
EvidenceHRBP was reported as a helper subunit in the HRT1 rubber-particle complex.
BoundaryComplex-support evidence, not a stand-alone catalytic claim.
Source10.7554/eLife.19022
A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.
The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.
22 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.
| Species and material | Reference gene / sequence ID | Pathway step | Evidence and boundary | Source |
|---|---|---|---|---|
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | HRBPLC057267CPTL | CPT/CPTL branchHRT1-complex helper subunit | A_direct_experiment HRBP was reported as a helper subunit in the HRT1 rubber-particle complex. Complex-support evidence, not a stand-alone catalytic claim. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | HRT1BAB71776.2;AB061234.3CPT | CPT/CPTL branchRubber-particle cis-prenyltransferase | A_direct_experiment HRT1 showed in-vitro rubber-transferase activity on detergent-washed rubber particles, with higher activity for the HRT1-REF-HRBP complex. Direct evidence in Hevea rubber particles; not direct validation in rubber dandelion. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCBPMF688938;ATD87120CPTL | CPT/CPTL branchGuayule CPT-complex helper subunit | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Helper-subunit evidence must retain the assay context. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT1MF688933;ATD87115CPT | CPT/CPTL branchForms a cis-prenyltransferase complex with PaCBP | A_direct_experiment PaCPT1 and PaCBP formed an active cis-prenyltransferase complex in heterologous and in-vitro systems. Assay-dependent external evidence; not in-plant rubber-yield proof. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT2MF688936;ATD87118CPT | CPT/CPTL branchForms a cis-prenyltransferase complex with PaCBP | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT3MF688934;ATD87116CPT | CPT/CPTL branchForms a cis-prenyltransferase complex with PaCBP | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT1JQ991925.1CPT | CPT/CPTL branchLaticifer-specific cis-prenyltransferase | A_direct_experiment TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion. External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT2JQ991926.1CPT | CPT/CPTL branchLaticifer-specific cis-prenyltransferase | A_direct_experiment TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion. External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT3JQ991927.1CPT | CPT/CPTL branchLaticifer-specific cis-prenyltransferase | A_direct_experiment TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion. External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assays | TbSRPP1JQ991928.1SRPP | REF/SRPP rubber-particle proteinsSmall rubber-particle protein | A_direct_experiment TbSRPP1 is a direct experimental reference associated with rubber-particle formation. External particle-protein evidence, not direct validation in T. kok-saghyz. | 10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation |
| Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic roots | EuIPIAB041629.2IDI | Prenyl-donor metabolismTrans-polyisoprene precursor-supply reference | A_direct_genetic_experiment EuIPI overexpression was associated with higher trans-polyisoprene accumulation. Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions. | 10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAOS RNAi and overexpression plants | AOS1X78166.2CYP74 | Latex/root associatedRegulatory candidate associated with rubber content and transferase activity | A_direct_genetic_experiment AOS down-regulation was associated with higher rubber content and rubber-transferase activity. RNAi specificity limitation remains; do not infer a single-gene universal mechanism. | 10.3389/fpls.2019.00760Silencing of allene oxide synthase in guayule increases rubber content and rubber transferase activity |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneLatex and recombinant enzyme | HRT2Q8W3U4;AB064661.2CPT | CPT/CPTL branchLatex-expressed cis-prenyltransferase reference | A_enzyme_experiment HRT2 is retained as a cis-prenyltransferase and latex-expression reference. Do not claim direct reconstitution of high-molecular-weight natural rubber by HRT2 alone. | 10.1046/j.1432-1033.2003.03863.xMolecular cloning expression and characterization of cDNA encoding cis-prenyltransferases from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | REFREF complex memberREF | REF/SRPP rubber-particle proteinsRubber-particle complex member | A_complex_evidence HRT1 and HRBP/REF particle-complex evidence; REF is not displayed as a stand-alone catalytic proof. Not a stand-alone catalytic proof. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaCBPPaTc_149493CPTL | CPT/CPTL branchCBP transcript reference in drought transcriptomics | B_omics_association PaCBP was reported in field bark transcriptomics under contrasting irrigation. Association only; transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaCPT1PaTc_044561CPT | CPT/CPTL branchCPT1 transcript reference in drought transcriptomics | B_omics_association PaCPT1 was reported in field bark transcriptomics under contrasting irrigation. Association only; transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaSRPP1PaTc_109994SRPP | REF/SRPP rubber-particle proteinsSRPP1 transcript reference in drought transcriptomics | B_omics_association Expression association is not converted into causal rubber-yield evidence. Transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| GuayuleParthenium argentatumcis-1,4-polyisopreneSRPP1 promoter reporter assay | PaSRPP1 promoterPV754023.1SRPP | REF/SRPP rubber-particle proteinsSRPP1 promoter regulatory reference | A_promoter_experiment Promoter sequence is regulatory reference evidence, not a complete gene-model crosswalk. Promoter record is not a complete SRPP1 gene model. | 10.1186/s13104-025-07448-0Functional characterization of the guayule SRPP1 promoter |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbRTAKP763637.1RTA | Latex/root associatedRubber transferase activator reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbFDPS1KJ911908.1FDPS | Prenyl-donor metabolismPrenyl-donor synthesis reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbFDPS2KJ911910.1FDPS | Prenyl-donor metabolismPrenyl-donor synthesis reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbREFMF471639.1REF | REF/SRPP rubber-particle proteinsRubber-particle protein reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
380 candidates match the current filter; 10 are shown per page (page 4 of 38). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.
| Gene ID | Pathway/step | Confidence | Evidence layers | Location | Key evidence | Actions |
|---|---|---|---|---|---|---|
TkA02G397010TK1151: TkA02G397010;TkA02G397070;TkA03G577920;TkA05G053790;TkA05G054080 OH-1004: LXL04_034492 |
Terpenoid metabolism Terpenoid metabolism |
High score 12 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104805.1:102913696-102917110 - |
GO:0016102 | |
LXL04_036527TK1151: - OH-1004: LXL04_036527 |
Terpenoid metabolism Terpenoid metabolism |
High score 12 |
GOExpressionLocalizationPfamSwiss-Prot | CM104806.1:43954772-43959250 - |
GO:0016102 | |
TkA01G610560TK1151: TkA01G610560;TkA01G610570 OH-1004: LXL04_000458 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104799.1:8503087-8506397 - |
GO:0010333 | |
TkA01G475480TK1151: TkA01G475480;TkA07G186220;TkA07G186860 OH-1004: LXL04_002187 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:43509327-43511401 + |
GO:0010333 | |
TkA01G402800TK1151: TkA01G402800 OH-1004: LXL04_003034 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:65386113-65404532 - |
go:0010686 tetracyclic triterpenoid biosynthetic process biological_process | |
TkA03G047320TK1151: TkA03G047320 OH-1004: LXL04_006545 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104800.1:13205270-13206421 - |
GO:0006720 | |
TkA03G206110TK1151: TkA03G206110 OH-1004: LXL04_007686 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104800.1:56186542-56192619 + |
go:0010686 tetracyclic triterpenoid biosynthetic process biological_process | |
TkA03G462260TK1151: TkA03G462260 OH-1004: LXL04_009683 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104800.1:131179279-131183781 + |
GO:0006720 | |
TkA03G549520TK1151: TkA03G549520 OH-1004: LXL04_010801 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104800.1:153691413-153693571 + |
GO:0010333 | |
TkA03G549670TK1151: TkA03G549670 OH-1004: LXL04_010803 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104800.1:153749645-153752098 + |
GO:0010333 |
TkA02G397010LXL04_036527TkA01G610560TkA01G475480TkA01G402800TkA03G047320TkA03G206110TkA03G462260TkA03G549520TkA03G549670Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.