Para rubber tree · HRBP
Sequence IDLC057267
StepCPT/CPTL branch · CPTL
EvidenceHRBP was reported as a helper subunit in the HRT1 rubber-particle complex.
BoundaryComplex-support evidence, not a stand-alone catalytic claim.
Source10.7554/eLife.19022
Rubber Biosynthesis Focus
A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.
This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.
The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.
Cross-species Research Reference
4 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.
1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
| Species and material | Reference gene / sequence ID | Pathway step | Evidence and boundary | Source |
|---|---|---|---|---|
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | HRBPLC057267CPTL | CPT/CPTL branchHRT1-complex helper subunit | A_direct_experiment HRBP was reported as a helper subunit in the HRT1 rubber-particle complex. Complex-support evidence, not a stand-alone catalytic claim. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | HRT1BAB71776.2;AB061234.3CPT | CPT/CPTL branchRubber-particle cis-prenyltransferase | A_direct_experiment HRT1 showed in-vitro rubber-transferase activity on detergent-washed rubber particles, with higher activity for the HRT1-REF-HRBP complex. Direct evidence in Hevea rubber particles; not direct validation in rubber dandelion. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneLatex and recombinant enzyme | HRT2Q8W3U4;AB064661.2CPT | CPT/CPTL branchLatex-expressed cis-prenyltransferase reference | A_enzyme_experiment HRT2 is retained as a cis-prenyltransferase and latex-expression reference. Do not claim direct reconstitution of high-molecular-weight natural rubber by HRT2 alone. | 10.1046/j.1432-1033.2003.03863.xMolecular cloning expression and characterization of cDNA encoding cis-prenyltransferases from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | REFREF complex memberREF | REF/SRPP rubber-particle proteinsRubber-particle complex member | A_complex_evidence HRT1 and HRBP/REF particle-complex evidence; REF is not displayed as a stand-alone catalytic proof. Not a stand-alone catalytic proof. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
Para rubber tree · HRBP
Para rubber tree · HRT1
Para rubber tree · HRT2
Para rubber tree · REF
Pathway Navigation And Candidate Distribution
MVA · Mevalonate pathway
47
High 40 · Medium 3 · Low 4
MEP · MEP pathway
59
High 23 · Medium 0 · Low 36
IPP/DMAPP/FPP · Prenyl-donor metabolism
271
High 141 · Medium 83 · Low 47
CPT/CPTL · Cis-prenyltransferase branch
5
High 0 · Medium 0 · Low 5
REF/SRPP · Rubber-particle proteins
7
High 0 · Medium 0 · Low 7
Rubber · Rubber biosynthesis candidates
288
High 1 · Medium 287 · Low 0
Terpenoid · Terpenoid metabolism
380
High 72 · Medium 107 · Low 201
Latex/root · Latex/root associated candidates
4466
High 231 · Medium 1284 · Low 2951
Candidate Genes
377 candidates match the current filter; 10 are shown per page (page 38 of 38). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.
| Gene ID | Pathway/step | Confidence | Evidence layers | Location | Key evidence | Actions |
|---|---|---|---|---|---|---|
LXL04_038407TK1151: - OH-1004: LXL04_038407 |
MVA/MEP and isoprenoid MEP pathway |
Low score 2 |
FunctionExpressionLocalizationPfamSwiss-Prot | CM104807.1:39872730-39873734 + |
lxl04_038407 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650) | |
TkA04G440430TK1151: TkA04G440430 OH-1004: LXL04_038537 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
Low score 2 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104807.1:43533036-43535571 - |
go:0046246 terpene biosynthetic process biological_process | |
LXL04_038853TK1151: - OH-1004: LXL04_038853 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
Low score 2 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104807.1:51989440-51991302 - |
go:0051762 sesquiterpene biosynthetic process biological_process | |
TkA04G471660TK1151: TkA04G471660 OH-1004: LXL04_038854 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
Low score 2 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104807.1:52000583-52006478 - |
go:0051762 sesquiterpene biosynthetic process biological_process | |
LXL04_039158TK1151: - OH-1004: LXL04_039158 |
MVA/MEP and isoprenoid MEP pathway |
Low score 2 |
FunctionExpressionLocalizationPfamSwiss-Prot | CM104807.1:60999065-60999931 - |
lxl04_039158 similar to orf v: enzymatic polyprotein (figwort mosaic virus (strain dxs) ox=10650) | |
LXL04_039159TK1151: - OH-1004: LXL04_039159 |
MVA/MEP and isoprenoid MEP pathway |
Low score 2 |
FunctionExpressionLocalizationPfamSwiss-Prot | CM104807.1:61009944-61011361 + |
lxl04_039159 similar to orf vi: transactivator/viroplasmin protein (figwort mosaic virus (strain dxs) ox=10650) | |
LXL04_039603TK1151: - OH-1004: LXL04_039603 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
Low score 2 |
GOExpressionLocalizationSwiss-ProtCoexpression | JAJTUU010000017.1:563551-565853 + |
go:1904629 response to diterpene biological_process |
TkA04G440430
MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2
LXL04_038853
MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2
TkA04G471660
MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2
LXL04_039603
MVA/MEP and isoprenoidPrenyl-donor metabolismLow · score 2
Evidence Boundary
Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.