Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 36 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA07G125560
TK1151: TkA07G125560
OH-1004: LXL04_019793
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:40278774-40281027
-
go:0010494 cytoplasmic stress granule cellular_component
LXL04_019962
TK1151: -
OH-1004: LXL04_019962
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtCoexpression CM104802.1:45994384-45997738
+
go:0010494 cytoplasmic stress granule cellular_component
LXL04_020331
TK1151: -
OH-1004: LXL04_020331
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-Prot CM104802.1:66948436-66953540
+
go:0010078 maintenance of root meristem identity biological_process
TkA03G299440
TK1151: TkA03G299440
OH-1004: LXL04_020354
MVA/MEP and isoprenoid
MEP pathway
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:69841074-69842693
-
GO:0019288
TkA02G198510
TK1151: TkA02G198510
OH-1004: LXL04_020641
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:100548903-100551734
-
go:0048527 lateral root development biological_process
TkA05G279400
TK1151: TkA05G279400
OH-1004: LXL04_020642
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPI CM104802.1:100553263-100554275
-
go:0048527 lateral root development biological_process
TkA08G326850
TK1151: TkA08G326850
OH-1004: LXL04_020644
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:100563776-100569870
-
go:0048527 lateral root development biological_process
TkA05G279420
TK1151: TkA05G279420;TkA05G280710
OH-1004: LXL04_020645
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPI CM104802.1:100613387-100619305
-
go:0048527 lateral root development biological_process
TkAUNG094510
TK1151: TkAUNG094510;TkA03G119570;TkA05G298180;TkA05G298310;TkA06G041400
OH-1004: LXL04_020715
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtCoexpression CM104802.1:106844103-106845510
+
go:0009651 response to salt stress biological_process
LXL04_020722
TK1151: -
OH-1004: LXL04_020722
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtCoexpression CM104802.1:106918425-106918959
+
go:0009651 response to salt stress biological_process

TkA07G125560

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA07G125560
LocationCM104802.1:40278774-40281027 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

LXL04_019962

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104802.1:45994384-45997738 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

LXL04_020331

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104802.1:66948436-66953540 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA03G299440

MVA/MEP and isoprenoidMEP pathwayHigh · score 8
Source IDTkA03G299440
LocationCM104802.1:69841074-69842693 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0019288

TkA02G198510

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G198510
LocationCM104802.1:100548903-100551734 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0048527 lateral root development biological_process

TkA05G279400

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA05G279400
LocationCM104802.1:100553263-100554275 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0048527 lateral root development biological_process

TkA08G326850

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA08G326850
LocationCM104802.1:100563776-100569870 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0048527 lateral root development biological_process

TkA05G279420

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA05G279420;TkA05G280710
LocationCM104802.1:100613387-100619305 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0048527 lateral root development biological_process

TkAUNG094510

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG094510;TkA03G119570;TkA05G298180;TkA05G298310;TkA06G041400
LocationCM104802.1:106844103-106845510 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

LXL04_020722

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104802.1:106918425-106918959 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.