Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Examples TkA01G624900 LXL04_000258

Download current filtered candidate TSV

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.

2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.

3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.

Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.

1Hardy rubber treeClick to view · 1 sources · trans-1,4-polyisoprene

Download current cross-species reference TSV

Species and material	Reference gene / sequence ID	Pathway step	Evidence and boundary	Source
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic roots	`EuIPI`AB041629.2IDI	Prenyl-donor metabolismTrans-polyisoprene precursor-supply reference	A_direct_genetic_experiment EuIPI overexpression was associated with higher trans-polyisoprene accumulation. Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.	10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2

StepPrenyl-donor metabolism · IDI

EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.

BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Source10.1186/1472-6750-12-78

Pathway Navigation And Candidate Distribution

MVA · Mevalonate pathway

High 40 · Medium 3 · Low 4 MEP · MEP pathway

High 23 · Medium 0 · Low 36 IPP/DMAPP/FPP · Prenyl-donor metabolism

271

High 141 · Medium 83 · Low 47 CPT/CPTL · Cis-prenyltransferase branch

High 0 · Medium 0 · Low 5 REF/SRPP · Rubber-particle proteins

High 0 · Medium 0 · Low 7 Rubber · Rubber biosynthesis candidates

288

High 1 · Medium 287 · Low 0 Terpenoid · Terpenoid metabolism

380

High 72 · Medium 107 · Low 201 Latex/root · Latex/root associated candidates

4466

High 231 · Medium 1284 · Low 2951

377 MVA/MEP and isoprenoid

Click to filter · High 204 · Medium 86 · Low 87 4466 Latex/root related candidates

Click to filter · High 231 · Medium 1284 · Low 2951 300 Rubber biosynthesis

Click to filter · High 1 · Medium 287 · Low 12 380 Terpenoid metabolism

Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

377 candidates match the current filter; 10 are shown per page (page 2 of 38). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene ID	Pathway/step	Confidence	Evidence layers	Location	Key evidence	Actions
`TkA03G447270` TK1151: TkA03G447270 OH-1004: LXL04_009548	MVA/MEP and isoprenoid MEP pathway	High score 20	FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104800.1:128773433-128775944 -	GO:0008299	Gene Card Expression Proteome JBrowse
`LXL04_018132` TK1151: - OH-1004: LXL04_018132	MVA/MEP and isoprenoid MEP pathway	High score 20	FunctionGOExpressionLocalizationSwiss-Prot	CM104802.1:7051568-7052066 +	GO:0008299	Gene Card Expression Proteome JBrowse
`TkA07G425430` TK1151: TkA07G425430 OH-1004: LXL04_030713	MVA/MEP and isoprenoid MEP pathway	High score 20	FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:121251815-121254315 +	GO:0008299	Gene Card Expression Proteome JBrowse
`LXL04_037620` TK1151: - OH-1004: LXL04_037620	MVA/MEP and isoprenoid MEP pathway	High score 20	FunctionGOExpressionLocalizationSwiss-Prot	CM104807.1:16327381-16327879 -	GO:0008299	Gene Card Expression Proteome JBrowse
`TkA02G535660` TK1151: TkA02G535660 OH-1004: LXL04_012842	MVA/MEP and isoprenoid Mevalonate pathway	High score 18	FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104801.1:19628006-19630012 +	GO:0008299	Gene Card Expression Proteome JBrowse
`TkA02G448690` TK1151: TkA02G448690 OH-1004: LXL04_014183	MVA/MEP and isoprenoid Mevalonate pathway	High score 18	FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104801.1:43288238-43290024 +	GO:0008299	Gene Card Expression Proteome JBrowse
`LXL04_028189` TK1151: - OH-1004: LXL04_028189	MVA/MEP and isoprenoid Mevalonate pathway	High score 18	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:33787973-33788663 -	GO:0008299	Gene Card Expression Proteome JBrowse
`LXL04_028191` TK1151: - OH-1004: LXL04_028191	MVA/MEP and isoprenoid Mevalonate pathway	High score 18	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:33794453-33797605 -	GO:0008299	Gene Card Expression Proteome JBrowse
`TkA07G129020` TK1151: TkA07G129020;TkA07G129240;TkA07G129470;TkA07G129530 OH-1004: LXL04_028201	MVA/MEP and isoprenoid Mevalonate pathway	High score 18	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104804.1:34323170-34326130 +	GO:0008299	Gene Card Expression Proteome JBrowse
`TkA01G499770` TK1151: TkA01G499770 OH-1004: LXL04_001903	MVA/MEP and isoprenoid Prenyl-donor metabolism	High score 16	GOExpressionLocalizationPfamSwiss-ProtPPICoexpression	CM104799.1:36531195-36533379 -	GO:0008299	Gene Card Expression Proteome JBrowse

`TkA03G447270`

MVA/MEP and isoprenoidMEP pathwayHigh · score 20

Source IDTkA03G447270

LocationCM104800.1:128773433-128775944 -

EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`LXL04_018132`

MVA/MEP and isoprenoidMEP pathwayHigh · score 20

Source ID-

LocationCM104802.1:7051568-7052066 +

EvidenceFunctionGOExpressionLocalizationSwiss-Prot

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`TkA07G425430`

MVA/MEP and isoprenoidMEP pathwayHigh · score 20

Source IDTkA07G425430

LocationCM104804.1:121251815-121254315 +

EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`LXL04_037620`

MVA/MEP and isoprenoidMEP pathwayHigh · score 20

Source ID-

LocationCM104807.1:16327381-16327879 -

EvidenceFunctionGOExpressionLocalizationSwiss-Prot

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`TkA02G535660`

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 18

Source IDTkA02G535660

LocationCM104801.1:19628006-19630012 +

EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`TkA02G448690`

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 18

Source IDTkA02G448690

LocationCM104801.1:43288238-43290024 +

EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`LXL04_028189`

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 18

Source ID-

LocationCM104804.1:33787973-33788663 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`LXL04_028191`

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 18

Source ID-

LocationCM104804.1:33794453-33797605 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`TkA07G129020`

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 18

Source IDTkA07G129020;TkA07G129240;TkA07G129470;TkA07G129530

LocationCM104804.1:34323170-34326130 +

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

`TkA01G499770`

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 16

Source IDTkA01G499770

LocationCM104799.1:36531195-36533379 -

EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression

Key evidenceGO:0008299

Gene Card Expression Proteome JBrowse

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.