Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 89 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_024910
TK1151: -
OH-1004: LXL04_024910
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:102022825-102024502
-
GO:0016114
TkA06G095920
TK1151: TkA06G095920
OH-1004: LXL04_024914
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:102100691-102102381
-
GO:0016114
TkA02G569700
TK1151: TkA02G569700;TkA06G095890
OH-1004: LXL04_024915
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:102156806-102160891
+
GO:0016740
TkA06G095380
TK1151: TkA06G095380
OH-1004: LXL04_024926
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:102264354-102264800
-
go:0006970 response to osmotic stress biological_process
TkA06G005810
TK1151: TkA06G005810;TkA06G095220
OH-1004: LXL04_024928
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:102325648-102326064
-
go:0006970 response to osmotic stress biological_process
TkA06G086050
TK1151: TkA06G086050
OH-1004: LXL04_025037
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:104470277-104471758
+
GO:0008299
TkA06G067740
TK1151: TkA06G067740
OH-1004: LXL04_025317
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:109715109-109716022
-
go:0006970 response to osmotic stress biological_process
LXL04_025537
TK1151: -
OH-1004: LXL04_025537
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:113082879-113084220
+
go:0048364 root development biological_process
TkA06G008530
TK1151: TkA06G008530;TkA06G046160
OH-1004: LXL04_025675
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:115083477-115085192
+
GO:0016114
TkA06G008530
TK1151: TkA06G008530;TkA06G046160
OH-1004: LXL04_025675
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:115083477-115085192
+
GO:0016114

LXL04_024910

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104803.1:102022825-102024502 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G095920

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G095920
LocationCM104803.1:102100691-102102381 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G569700

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G569700;TkA06G095890
LocationCM104803.1:102156806-102160891 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA06G095380

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G095380
LocationCM104803.1:102264354-102264800 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA06G005810

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G005810;TkA06G095220
LocationCM104803.1:102325648-102326064 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA06G086050

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G086050
LocationCM104803.1:104470277-104471758 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA06G067740

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G067740
LocationCM104803.1:109715109-109716022 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

LXL04_025537

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104803.1:113082879-113084220 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

TkA06G008530

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA06G008530;TkA06G046160
LocationCM104803.1:115083477-115085192 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G008530

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G008530;TkA06G046160
LocationCM104803.1:115083477-115085192 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.