Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 69 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkAUNG065560
TK1151: TkAUNG065560;TkA03G555060;TkA07G092420
OH-1004: LXL04_010909
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:155077373-155080581
+
go:0009611 response to wounding biological_process
TkA03G557100
TK1151: TkA03G557100
OH-1004: LXL04_010941
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:155381523-155381954
-
go:0006970 response to osmotic stress biological_process
TkA03G570170
TK1151: TkA03G570170
OH-1004: LXL04_011171
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:159325501-159325935
+
go:0006970 response to osmotic stress biological_process
LXL04_011172
TK1151: -
OH-1004: LXL04_011172
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:159327829-159328263
+
go:0006970 response to osmotic stress biological_process
TkA03G570230
TK1151: TkA03G570230
OH-1004: LXL04_011173
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:159350221-159350652
+
go:0006970 response to osmotic stress biological_process
TkA03G571550
TK1151: TkA03G571550;TkA08G016680
OH-1004: LXL04_011190
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:159679475-159681153
-
GO:0016114
TkA07G057730
TK1151: TkA07G057730
OH-1004: LXL04_011277
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationSwiss-Prot CM104800.1:161858672-161859433
-
go:0009611 response to wounding biological_process
TkA03G586380
TK1151: TkA03G586380
OH-1004: LXL04_011410
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:163895637-163898087
-
go:0006970 response to osmotic stress biological_process
TkA03G601290
TK1151: TkA03G601290;TkA05G334260
OH-1004: LXL04_011552
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:167147244-167149164
+
go:0006970 response to osmotic stress biological_process
LXL04_011607
TK1151: -
OH-1004: LXL04_011607
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:168101516-168102943
+
GO:0016114

TkAUNG065560

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkAUNG065560;TkA03G555060;TkA07G092420
LocationCM104800.1:155077373-155080581 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA03G557100

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G557100
LocationCM104800.1:155381523-155381954 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G570170

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G570170
LocationCM104800.1:159325501-159325935 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

LXL04_011172

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104800.1:159327829-159328263 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G570230

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G570230
LocationCM104800.1:159350221-159350652 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G571550

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G571550;TkA08G016680
LocationCM104800.1:159679475-159681153 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA07G057730

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA07G057730
LocationCM104800.1:161858672-161859433 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidencego:0009611 response to wounding biological_process

TkA03G586380

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G586380
LocationCM104800.1:163895637-163898087 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G601290

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G601290;TkA05G334260
LocationCM104800.1:167147244-167149164 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

LXL04_011607

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:168101516-168102943 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.