Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 58 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkAUNG070970
TK1151: TkAUNG070970
OH-1004: LXL04_004180
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:127707209-127709639
-
go:0006979 response to oxidative stress biological_process
TkAUNG088930
TK1151: TkAUNG088930;TkA01G185090;TkA05G084790
OH-1004: LXL04_004202
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:129071293-129073164
+
GO:0016740
TkA01G174920
TK1151: TkA01G174920
OH-1004: LXL04_004281
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:131685419-131688990
+
GO:0016114
TkA01G174920
TK1151: TkA01G174920
OH-1004: LXL04_004281
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:131685419-131688990
+
GO:0016114
TkA01G040610
TK1151: TkA01G040610
OH-1004: LXL04_004327
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:132670302-132671969
+
GO:0016114
TkA01G040610
TK1151: TkA01G040610
OH-1004: LXL04_004327
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:132670302-132671969
+
GO:0016114
LXL04_004546
TK1151: -
OH-1004: LXL04_004546
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:139807081-139808251
+
GO:0016740
TkA01G119700
TK1151: TkA01G119700
OH-1004: LXL04_004711
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot CM104799.1:144307202-144308805
+
GO:0016114
TkA01G119700
TK1151: TkA01G119700
OH-1004: LXL04_004711
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot CM104799.1:144307202-144308805
+
GO:0016114
TkA01G116310
TK1151: TkA01G116310
OH-1004: LXL04_004742
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:145247847-145250098
-
go:0004659 prenyltransferase activity molecular_function

TkAUNG070970

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkAUNG070970
LocationCM104799.1:127707209-127709639 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkAUNG088930

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG088930;TkA01G185090;TkA05G084790
LocationCM104799.1:129071293-129073164 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA01G174920

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA01G174920
LocationCM104799.1:131685419-131688990 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA01G174920

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G174920
LocationCM104799.1:131685419-131688990 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA01G040610

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA01G040610
LocationCM104799.1:132670302-132671969 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA01G040610

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G040610
LocationCM104799.1:132670302-132671969 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

LXL04_004546

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104799.1:139807081-139808251 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA01G119700

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA01G119700
LocationCM104799.1:144307202-144308805 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016114

TkA01G119700

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G119700
LocationCM104799.1:144307202-144308805 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016114

TkA01G116310

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA01G116310
LocationCM104799.1:145247847-145250098 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0004659 prenyltransferase activity molecular_function

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.