Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 191 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA07G045610
TK1151: TkA07G045610
OH-1004: LXL04_027291
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:12631385-12635123
+
go:0006979 response to oxidative stress biological_process
LXL04_027341
TK1151: -
OH-1004: LXL04_027341
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:13935984-13940528
+
go:0009651 response to salt stress biological_process
TkA07G051970
TK1151: TkA07G051970
OH-1004: LXL04_027347
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:14047528-14051015
-
go:0009651 response to salt stress biological_process
TkA07G053350
TK1151: TkA07G053350
OH-1004: LXL04_027370
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:14391185-14394722
+
go:0010082 regulation of root meristem growth biological_process
TkA03G467470
TK1151: TkA03G467470
OH-1004: LXL04_027391
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:14803764-14811420
+
go:0006970 response to osmotic stress biological_process
LXL04_027400
TK1151: -
OH-1004: LXL04_027400
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationSwiss-Prot CM104804.1:14985781-14986085
-
go:0010494 cytoplasmic stress granule cellular_component
TkA07G070940
TK1151: TkA07G070940;TkA07G088860;TkA08G419110
OH-1004: LXL04_027526
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:18203627-18211513
-
go:0016104 triterpenoid biosynthetic process biological_process
LXL04_027542
TK1151: -
OH-1004: LXL04_027542
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationSwiss-Prot CM104804.1:18507862-18509777
-
go:0016104 triterpenoid biosynthetic process biological_process
TkA03G571030
TK1151: TkA03G571030
OH-1004: LXL04_027549
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:18719899-18729043
+
go:0016104 triterpenoid biosynthetic process biological_process
TkA07G085290
TK1151: TkA07G085290
OH-1004: LXL04_027678
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:21699821-21701897
+
go:0016114 terpenoid biosynthetic process biological_process

TkA07G045610

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G045610
LocationCM104804.1:12631385-12635123 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

LXL04_027341

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source ID-
LocationCM104804.1:13935984-13940528 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA07G051970

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G051970
LocationCM104804.1:14047528-14051015 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA07G053350

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G053350
LocationCM104804.1:14391185-14394722 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010082 regulation of root meristem growth biological_process

TkA03G467470

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA03G467470
LocationCM104804.1:14803764-14811420 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

LXL04_027400

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source ID-
LocationCM104804.1:14985781-14986085 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidencego:0010494 cytoplasmic stress granule cellular_component

TkA07G070940

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA07G070940;TkA07G088860;TkA08G419110
LocationCM104804.1:18203627-18211513 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

LXL04_027542

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source ID-
LocationCM104804.1:18507862-18509777 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

TkA03G571030

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA03G571030
LocationCM104804.1:18719899-18729043 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

TkA07G085290

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA07G085290
LocationCM104804.1:21699821-21701897 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.