Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 151 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA02G561730
TK1151: TkA02G561730
OH-1004: LXL04_012430
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:12155147-12156779
-
go:0009611 response to wounding biological_process
TkA02G557130
TK1151: TkA02G557130
OH-1004: LXL04_012508
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:13464267-13465491
+
go:0009651 response to salt stress biological_process
TkA02G552550
TK1151: TkA02G552550
OH-1004: LXL04_012572
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:14829752-14831305
+
go:0010078 maintenance of root meristem identity biological_process
TkA02G548640
TK1151: TkA02G548640
OH-1004: LXL04_012632
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:15906843-15908540
+
go:0016114 terpenoid biosynthetic process biological_process
TkA02G544490
TK1151: TkA02G544490
OH-1004: LXL04_012701
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:17266182-17267657
+
go:0010078 maintenance of root meristem identity biological_process
TkAUNG045740
TK1151: TkAUNG045740;TkA01G323340;TkA01G324210;TkA02G542970
OH-1004: LXL04_012713
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:17585416-17591695
-
go:0048364 root development biological_process
TkA02G542410
TK1151: TkA02G542410;TkA06G088300
OH-1004: LXL04_012716
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:17775239-17777355
+
go:0006970 response to osmotic stress biological_process
TkA02G541220
TK1151: TkA02G541220
OH-1004: LXL04_012729
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:17909369-17913672
-
go:0009611 response to wounding biological_process
TkAUNG002310
TK1151: TkAUNG002310;TkA02G540420;TkA07G060160;TkA08G080250
OH-1004: LXL04_012742
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:18064907-18068909
+
go:0010082 regulation of root meristem growth biological_process
TkA02G539140
TK1151: TkA02G539140
OH-1004: LXL04_012787
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:18745783-18752335
-
go:0010078 maintenance of root meristem identity biological_process

TkA02G561730

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G561730
LocationCM104801.1:12155147-12156779 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G557130

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G557130
LocationCM104801.1:13464267-13465491 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA02G552550

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G552550
LocationCM104801.1:14829752-14831305 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA02G548640

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkA02G548640
LocationCM104801.1:15906843-15908540 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA02G544490

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G544490
LocationCM104801.1:17266182-17267657 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkAUNG045740

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkAUNG045740;TkA01G323340;TkA01G324210;TkA02G542970
LocationCM104801.1:17585416-17591695 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

TkA02G542410

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G542410;TkA06G088300
LocationCM104801.1:17775239-17777355 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA02G541220

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G541220
LocationCM104801.1:17909369-17913672 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkAUNG002310

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkAUNG002310;TkA02G540420;TkA07G060160;TkA08G080250
LocationCM104801.1:18064907-18068909 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010082 regulation of root meristem growth biological_process

TkA02G539140

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G539140
LocationCM104801.1:18745783-18752335 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.