LXL04_038537 | RubberDandelionOmics

Gene overview

LXL04_038537

Reference: OH-1004 Chr: Chr09 Coordinates: 43533036-43535571 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

1566 bp · LXL04_038537|LXL04_038537|OH1004|cDNA

ATGGAGTTGAAGATATTACAACAATACATATTAGGAGGAATCATAGCTACTTGGTTAGGTTTCACTCTCATCTATTTATTGGGTGTAAAAAAGAGCAAACCTGATGATGGTTTGCATGTGCATAAACAGACCAATGAGTTAGTTAGGACTCAACCACAAAAAGATGGAGGCATTGACGTTATCATAGTTGGTGCAGGTGTTGCTGGTGCAGCCCTTGCCTATAGTCTTGGCAAGGATGGAAGACGAATTCTTGTCATCGA...

CDS

Download CDS FASTA

1566 bp · LXL04_038537|LXL04_038537|OH1004|CDS

ATGGAGTTGAAGATATTACAACAATACATATTAGGAGGAATCATAGCTACTTGGTTAGGTTTCACTCTCATCTATTTATTGGGTGTAAAAAAGAGCAAACCTGATGATGGTTTGCATGTGCATAAACAGACCAATGAGTTAGTTAGGACTCAACCACAAAAAGATGGAGGCATTGACGTTATCATAGTTGGTGCAGGTGTTGCTGGTGCAGCCCTTGCCTATAGTCTTGGCAAGGATGGAAGACGAATTCTTGTCATCGA...

Protein

Download Protein FASTA

521 aa · LXL04_038537|LXL04_038537|OH1004|PROTEIN

MELKILQQYILGGIIATWLGFTLIYLLGVKKSKPDDGLHVHKQTNELVRTQPQKDGGIDVIIVGAGVAGAALAYSLGKDGRRILVIERDLGLQDRIVGELLQPGGFMKLIDLGLEDCVEDIDAQKVFGYALFKDDKSTSLAYPLEKYTRDVAGRSFHNGRFVQRMREKAATVSSVRLEEGTVTSLVEEKGVVRGVRYKTKSGQDITANAPLTIVCDGCFSNLRRGLCKPEVDIPSSFAALLLKNCEAPYPNHGHVILADP...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`LXL04_038537`
TK1151 ID	TkA04G440430
OH-1004 ID	LXL04_038537
Relationship / confidence	Multi Source To Oh1004 / Complex relationship
Protein identity (%)	99.800
Protein coverage (%)	TK1151 100.000 / OH-1004 100.000 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	OH-1004 / GCA_047496595.1_OSU_TarKok_2.0

Open Full ID Mapping

SNP / Indel variants and carrier samplesCRA009020 · OH-1004

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID LXL04_038537

Location Chr09:43533036-43535571 (-)

Description Similar to SQE1: Squalene monooxygenase SE1

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At2g22830`	Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.	Arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development.2007 · DOI: 10.1074/jbc.m611831200
`At1g58440`	May catalyze stereospecific oxidation of squalene to (S)-2,3-epoxysqualene in sterol biosynthesis.	Arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development.2007 · DOI: 10.1074/jbc.m611831200 Identification of the Arabidopsis dry2/sqe1-5 mutant reveals a central role for sterols in drought tolerance and regulation of reactive oxygen species.2009 · DOI: 10.1111/j.1365-313x.2009.03849.x Analysis of the arabidopsis dry2/sqe1-5 mutant suggests a role for sterols in signaling.2009 · DOI: 10.4161/psb.4.9.9425
`At4g37760`	May catalyze stereospecific oxidation of squalene to (S)-2,3-epoxysqualene in sterol biosynthesis.	Arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development.2007 · DOI: 10.1074/jbc.m611831200

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_038537 · GCA_047496595.1_OSU_TarKok_2.0.

GO annotations (OH1004 source)

GO:0002238 response to molecule of fungal origin Biological Process

GO:0009414 response to water deprivation Biological Process

GO:0009611 response to wounding Biological Process

GO:0009723 response to ethylene Biological Process

GO:0009725 response to hormone Biological Process

GO:0009751 response to salicylic acid Biological Process

GO:0009753 response to jasmonic acid Biological Process

GO:0010038 response to metal ion Biological Process

GO:0016126 sterol biosynthetic process Biological Process

GO:0042542 response to hydrogen peroxide Biological Process

GO:0046246 terpene biosynthetic process Biological Process

GO:0071731 response to nitric oxide Biological Process

KEGG gene cross-reference

ath:AT1G58440

ath:AT2G22830

ath:AT4G37760

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.432

Rank 1 · LXL04_038537 · OH-1004

Mitochondrion0.252

Rank 2 · LXL04_038537 · OH-1004

Cytoplasm0.136

Rank 3 · LXL04_038537 · OH-1004

Cell membrane0.093

Rank 4 · LXL04_038537 · OH-1004

Nucleus0.085

Rank 5 · LXL04_038537 · OH-1004

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF01494.26FAD_binding_359-365 aa

PF01266.31DAO59-89 aa

PF08491.17SE209-477 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
LXL04_038537	`PF01494.26`	FAD_binding_3	59	365	1.3e-11	45.1
LXL04_038537	`PF01266.31`	DAO	59	89	2.1e-11	44.7
LXL04_038537	`PF08491.17`	SE	209	477	1.5e-111	372.7

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`O81000`	Arabidopsis thaliana	Squalene epoxidase 2, mitochondrial	66.602%	Swiss-Prot	strong database homology
`Q9SM02`	Arabidopsis thaliana	Squalene epoxidase 1	68.455%	Swiss-Prot	strong database homology
`Q8VYH2`	Arabidopsis thaliana	Squalene epoxidase 3	67.258%	Swiss-Prot	strong database homology

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