TkA08G434230 | RubberDandelionOmics

Gene overview

TkA08G434230

Reference: TK1151 Chr: Chr08 Coordinates: 110365177-110366308 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

708 bp · TkA08G434230|TK1151|cDNA

TTTCTAATTAACGAGGCCTTAGATATAATCGAAGCTGCAGGCGGCTGCTTCCATCTGGTCAAATGTCAAGTCGGTCAAGGCTCGGAACTCGAAGTAGATGCAGATGACGGTGCGGTCCTTGATAAAATAGTTGATACTTTGACTTGTAACTGTATAGCAAACTCAAAGGAAGGAAAGAACACGGTTCTTGTGTTAGGTGCAGGGCGTGTTTGTCAACCTGCTGCTGTTGAACTTTTGGCTTCAATTGGAAGCGATTCATC...

CDS

Download CDS FASTA

708 bp · TkA08G434230|TK1151|CDS

TTTCTAATTAACGAGGCCTTAGATATAATCGAAGCTGCAGGCGGCTGCTTCCATCTGGTCAAATGTCAAGTCGGTCAAGGCTCGGAACTCGAAGTAGATGCAGATGACGGTGCGGTCCTTGATAAAATAGTTGATACTTTGACTTGTAACTGTATAGCAAACTCAAAGGAAGGAAAGAACACGGTTCTTGTGTTAGGTGCAGGGCGTGTTTGTCAACCTGCTGCTGTTGAACTTTTGGCTTCAATTGGAAGCGATTCATC...

Protein

Download Protein FASTA

235 aa · TkA08G434230|TK1151|PROTEIN

FLINEALDIIEAAGGCFHLVKCQVGQGSELEVDADDGAVLDKIVDTLTCNCIANSKEGKNTVLVLGAGRVCQPAAVELLASIGSDSSPDWIKSCGVGEFQEQNCVEVIVASLFLKDAEEIVEGIPDTIACELDVMDHDSFYKYINQVDIVISLLPLSFHSTIANVCIELKKHPVTASYVNDSMYKLHEAGKDCDITLLGEMGLDPGIDHMMAMKMINEARAQGGYTCILYLFPEF

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA08G434230`
TK1151 ID	TkA08G434230
OH-1004 ID	LXL04_002260
Relationship / confidence	Non Reciprocal Best Hit / Complex relationship
Protein identity (%)	77.900
Protein coverage (%)	TK1151 95.319 / OH-1004 24.786 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

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Basic Information and Functional Annotation

Gene ID TkA08G434230

Location Chr08:110365177-110366308 (-)

Description Similar to LKR/SDH: Alpha-aminoadipic semialdehyde synthase

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At4g33150`	Bifunctional enzyme that catalyzes the first two steps in lysine degradation.	A T-DNA insertion knockout of the bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase gene elevates lysine levels in Arabidopsis seeds.2001 · DOI: 10.1104/pp.126.4.1539

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_002260 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0006091 generation of precursor metabolites and energy Biological Process

GO:0006554 lysine catabolic process Biological Process

GO:0019477 L-lysine catabolic process Biological Process

GO:0019878 L-lysine biosynthetic process via aminoadipic acid Biological Process

GO:0033512 L-lysine catabolic process to acetyl-CoA via L-saccharopine Biological Process

GO:0005737 cytoplasm Cellular Component

GO:0005739 mitochondrion Cellular Component

GO:0005829 cytosol Cellular Component

GO:0004753 saccharopine dehydrogenase activity Molecular Function

GO:0047130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity Molecular Function

GO:0047131 saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity Molecular Function

KEGG gene cross-reference

ath:AT4G33150

bta:520865

mmu:30956

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.447

Rank 1 · TkA08G434230 · TK1151

Nucleus0.201

Rank 2 · TkA08G434230 · TK1151

Extracellular0.115

Rank 3 · TkA08G434230 · TK1151

Plastid0.106

Rank 4 · TkA08G434230 · TK1151

Endoplasmic reticulum0.091

Rank 5 · TkA08G434230 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

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Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF04455Saccharop_dh_N2-50 aa

PF24180Avr211-35 aa

PF23755Ig-like_IP5PC_F25-65 aa

PF01488Shikimate_DH59-80 aa

PF03435Sacchrp_dh_NADP62-80 aa

PF23755Ig-like_IP5PC_F87-133 aa

PF01488Shikimate_DH99-152 aa

PF11573Med23104-181 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA08G434230	`PF04455`	Saccharop_dh_N	2	50	2.4e-06	28.6
TkA08G434230	`PF24180`	Avr2	11	35	0.06	13.9
TkA08G434230	`PF23755`	Ig-like_IP5PC_F	25	65	0.0048	17.4
TkA08G434230	`PF01488`	Shikimate_DH	59	80	0.069	13.9
TkA08G434230	`PF03435`	Sacchrp_dh_NADP	62	80	2.9e-14	54.2
TkA08G434230	`PF23755`	Ig-like_IP5PC_F	87	133	0.0048	17.4
TkA08G434230	`PF01488`	Shikimate_DH	99	152	0.069	13.9
TkA08G434230	`PF11573`	Med23	104	181	0.13	10.7
TkA08G434230	`PF03435`	Sacchrp_dh_NADP	105	197	2.9e-14	54.2
TkA08G434230	`PF24180`	Avr2	143	178	0.06	13.9
TkA08G434230	`PF16653`	Sacchrp_dh_C	202	224	5.6e-05	23.9
TkA08G434230	`PF03435`	Sacchrp_dh_NADP	208	222	2.9e-14	54.2

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`Q9SMZ4`	Arabidopsis thaliana	sp\|Q9SMZ4\|AASS_ARATH Alpha-aminoadipic semialdehyde synthase	52.700%	Swiss-Prot	High

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