Gene Card
Gene overview
cDNA / CDS / Protein Sequences
5947 bp · TkA06G457360|TK1151|cDNA
ATTAACTGATAACATCCATCCCAAACGATCGCCTTCTTCAACAACGACTCCCGATCAATCGTCGAGTTCAACAACAACTGAGATTCAATAATCCTAACATCCATCCCAAAGATGGTCTGGTGCATGTCCGGAGACACCATATTGTTTCAACGTGGATTTACACCGCTTCATTGAAGTATTTGAAGCGACGGAAACCATTTGCAACCAACGATGAAATCAGAAAAAGCTGCTAAACACCAACTAACATATCAGCATCAAGC...
3117 bp · TkA06G457360|TK1151|CDS
ATGGAAAAGTTTGCAGAACGCTATTGTATATGTAATCCCAAGGCGTTTATTAGTGCTGATACGGCTTATGTTCTTGCTTACTCTGTTATTATGCTAAATACTGATGCTCATAATCCCATGGTCAAGAATAAGATGTCAGCTGATGACTTCATAAGAAACAACCGTGGCATAGATGACGGAAAAGATTTACCAGAGGAGTACCTGCGATCATTATTCGAACGAATATCAAGAAGTGAGATAAAAATGAAAGAAGACGATTT...
Protein
Download Protein FASTA1038 aa · TkA06G457360|TK1151|PROTEIN
MEKFAERYCICNPKAFISADTAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPEEYLRSLFERISRSEIKMKEDDLALQQSLSVNSNKILGLDSILNIVVRKRDEETHTSEDLMRHMQQQFQEKARRSESVYYAATDVFILRYMIEVCWAPMLVAFSVPLDKSDDVIVITKCLEGFRHAVHVTSAMSMKTHRDAFVTSLAKFTSLHSPADIKQKNIDAIKVIVTIADEDGDYLQEAWEHILTCISRFEQ...
Flanking Sequence Download
Sequence orientation and download details
Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.
ID Mapping
| Input ID | TkA06G457360 |
|---|---|
| TK1151 ID | TkA06G457360 |
| OH-1004 ID | LXL04_022727 |
| Relationship / confidence | Sequence Supported Annotation Or Model Conflict / Review |
| Protein identity (%) | 99.400 |
| Protein coverage (%) | TK1151 100.000 / OH-1004 58.810Coverage and evidenceCoverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation. |
| Source version | TK1151 / GWHBCHF00000000 |
SNP / Indel variants and carrier samplesCRA009020 · TK1151
Expand to load variant records for this gene.
Basic Information and Functional Annotation
| Gene ID | TkA06G457360 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Location | Chr06:113076396-113094893 (+) | ||||||||||||||||||
| Description | Similar to BIG2: Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | ||||||||||||||||||
| Arabidopsis / Rice Reference Genes and Papers |
Download references for this gene Arabidopsis
RiceNo hit for this species in the current source table. | ||||||||||||||||||
| Functional annotation source | View annotation sourcesFunctional annotation source: OH1004 · | ||||||||||||||||||
| GO annotations (OH1004 source) | GO:0001881 receptor recycling Biological Process GO:0006887 exocytosis Biological Process GO:0006893 Golgi to plasma membrane transport Biological Process GO:0007032 endosome organization Biological Process GO:0009561 megagametogenesis Biological Process GO:0010256 endomembrane system organization Biological Process GO:0015031 protein transport Biological Process GO:0016192 vesicle-mediated transport Biological Process GO:0032012 regulation of ARF protein signal transduction Biological Process GO:0032760 positive regulation of tumor necrosis factor production Biological Process GO:0035556 intracellular signal transduction Biological Process GO:0043001 Golgi to plasma membrane protein transport Biological Process | ||||||||||||||||||
| KEGG gene cross-reference | ath:AT1G01960 ath:AT3G60860 ath:AT4G35380 ath:AT4G38200 hsa:10564 These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene. |
Gene expression
View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.
Data sources and gene correspondence
Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.
Subcellular Localization Top 5
Computational predictions or homology annotations below do not replace localization experiments.
LocPro · Direct prediction · Computational prediction, not experimental localization
Predicted Functional Domains
Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.
PF01369Sec71-80 aaPF02916DNA_PPF194-251 aaPF09324Sec7-like_HDS217-257 aaPF20252BIG2_C336-359 aaPF23325TPR_28359-416 aaPF09324Sec7-like_HDS385-415 aaPF16206Mon2_C399-449 aaPF21822Phage_TAC_15441-525 aa| Gene ID | Domain ID | Domain Name | Start aa | End aa | E-value | Score |
|---|---|---|---|---|---|---|
| TkA06G457360 | PF01369 | Sec7 | 1 | 80 | 2.6e-32 | 112.6 |
| TkA06G457360 | PF02916 | DNA_PPF | 194 | 251 | 0.096 | 13.5 |
| TkA06G457360 | PF09324 | Sec7-like_HDS | 217 | 257 | 9.3e-31 | 106.3 |
| TkA06G457360 | PF20252 | BIG2_C | 336 | 359 | 6.2e-39 | 134.5 |
| TkA06G457360 | PF23325 | TPR_28 | 359 | 416 | 6.5e-08 | 33.4 |
| TkA06G457360 | PF09324 | Sec7-like_HDS | 385 | 415 | 9.3e-31 | 106.3 |
| TkA06G457360 | PF16206 | Mon2_C | 399 | 449 | 2.5e-08 | 33.3 |
| TkA06G457360 | PF21822 | Phage_TAC_15 | 441 | 525 | 0.018 | 16.3 |
| TkA06G457360 | PF09324 | Sec7-like_HDS | 443 | 525 | 9.3e-31 | 106.3 |
| TkA06G457360 | PF28349 | HSF2BP_C | 456 | 480 | 1.3 | 10.2 |
| TkA06G457360 | PF23325 | TPR_28 | 460 | 496 | 6.5e-08 | 33.4 |
| TkA06G457360 | PF02985 | HEAT | 462 | 487 | 0.028 | 15.4 |
| TkA06G457360 | PF20252 | BIG2_C | 518 | 556 | 6.2e-39 | 134.5 |
| TkA06G457360 | PF16206 | Mon2_C | 542 | 690 | 2.5e-08 | 33.3 |
| TkA06G457360 | PF23325 | TPR_28 | 626 | 732 | 6.5e-08 | 33.4 |
| TkA06G457360 | PF02985 | HEAT | 629 | 658 | 0.028 | 15.4 |
Arabidopsis / Rice Protein Homology
Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.
| Protein | Organism | Description | Identity | Database | Confidence |
|---|---|---|---|---|---|
Q9LZX8 | Arabidopsis thaliana | sp|Q9LZX8|BIG2_ARATH Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | 67.100% | Swiss-Prot | High |
Q9LPC5 | Arabidopsis thaliana | sp|Q9LPC5|BIG3_ARATH Brefeldin A-inhibited guanine nucleotide-exchange protein 3 | 63.800% | Swiss-Prot | High |
F4JSZ5 | Arabidopsis thaliana | sp|F4JSZ5|BIG1_ARATH Brefeldin A-inhibited guanine nucleotide-exchange protein 1 | 47.800% | Swiss-Prot | Medium |
F4JN05 | Arabidopsis thaliana | sp|F4JN05|BIG4_ARATH Brefeldin A-inhibited guanine nucleotide-exchange protein 4 | 46.700% | Swiss-Prot | Medium |
F4IXW2 | Arabidopsis thaliana | sp|F4IXW2|BIG5_ARATH Brefeldin A-inhibited guanine nucleotide-exchange protein 5 | 32.900% | Swiss-Prot | Medium |