TkA05G030450 | RubberDandelionOmics

Gene overview

TkA05G030450

Reference: TK1151 Chr: Chr05 Coordinates: 8231894-8233800 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

1209 bp · TkA05G030450|TK1151|cDNA

ATGGTGAGTGGGGAAAGCCGAGCACCAGCAATCGGCATTGACTTGGGCACGACCTACTCCTGTGTTGCTGTATGGAAACACGATCGAATCCAGATCATACCCAACGACCAAGGCAATCGAACTACACCATCTTGTGTTGCTTTCACAGATACTCAACGTCTTGTTGGCAATGGTGCAAAAAATCAAATCGCAAGGAACTCTGCTAACACTATATTCAATGCAAAGAGGTTGATCGGCAGGAGTTTCAATGACGTTATGGT...

CDS

Download CDS FASTA

1209 bp · TkA05G030450|TK1151|CDS

ATGGTGAGTGGGGAAAGCCGAGCACCAGCAATCGGCATTGACTTGGGCACGACCTACTCCTGTGTTGCTGTATGGAAACACGATCGAATCCAGATCATACCCAACGACCAAGGCAATCGAACTACACCATCTTGTGTTGCTTTCACAGATACTCAACGTCTTGTTGGCAATGGTGCAAAAAATCAAATCGCAAGGAACTCTGCTAACACTATATTCAATGCAAAGAGGTTGATCGGCAGGAGTTTCAATGACGTTATGGT...

Protein

Download Protein FASTA

402 aa · TkA05G030450|TK1151|PROTEIN

MVSGESRAPAIGIDLGTTYSCVAVWKHDRIQIIPNDQGNRTTPSCVAFTDTQRLVGNGAKNQIARNSANTIFNAKRLIGRSFNDVMVQEDIKLWPFRVIEGPTDMPIVAVTHKVPAYFNDCQRQATKDAATIAGLNVLRLINEPTAAAIAYAMDNSLSGKKNVLIFDLGGGTFDISLLAIDEACKFEVKAVAGDTHLGGEDFDDRLVNYCVADFKKKWKKDLSGNERALGKLKVACEKAKRILSYATEASIELDCLAEGI...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA05G030450`
TK1151 ID	TkA05G030450
OH-1004 ID	LXL04_019212
Relationship / confidence	Non Reciprocal Best Hit / Complex relationship
Protein identity (%)	54.500
Protein coverage (%)	TK1151 93.035 / OH-1004 93.802 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA05G030450

Location Chr05:8231894-8233800 (-)

Description Similar to HSC-2: Heat shock cognate 70 kDa protein 2

Arabidopsis / Rice Reference Genes and Papers

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Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At3g12580`	In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable).	Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family.2001 · DOI: 10.1104/pp.126.2.789 Heat shock protein cognate 70-4 and an E3 ubiquitin ligase, CHIP, mediate plastid-destined precursor degradation through the ubiquitin-26S proteasome system in Arabidopsis.2009 · DOI: 10.1105/tpc.109.071548
`At5g02500`	In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable).	Physiological and molecular assessment of altered expression of Hsc70-1 in Arabidopsis. Evidence for pleiotropic consequences.2003 · DOI: 10.1104/pp.102.019398 Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses.2007 · DOI: 10.1105/tpc.107.051896 WPP-domain proteins mimic the activity of the HSC70-1 chaperone in preventing mistargeting of RanGAP1-anchoring protein WIT1.2009 · DOI: 10.1104/pp.109.143404 The cytosolic/nuclear HSC70 and HSP90 molecular chaperones are important for stomatal closure and modulate abscisic acid-dependent physiological responses in Arabidopsis.2011 · DOI: 10.1104/pp.111.174425
`At3g09440`	In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions.	No verified direct reference in this release

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_019212 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0006351 DNA-templated transcription Biological Process

GO:0006457 protein folding Biological Process

GO:0006950 response to stress Biological Process

GO:0009266 response to temperature stimulus Biological Process

GO:0009408 response to heat Biological Process

GO:0009615 response to virus Biological Process

GO:0009617 response to bacterium Biological Process

GO:0010187 negative regulation of seed germination Biological Process

GO:0010286 heat acclimation Biological Process

GO:0016567 protein ubiquitination Biological Process

GO:0042026 protein refolding Biological Process

GO:0042742 defense response to bacterium Biological Process

KEGG gene cross-reference

ath:AT3G09440

ath:AT3G12580

ath:AT5G02500

sly:101247772

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.561

Rank 1 · TkA05G030450 · TK1151

Nucleus0.334

Rank 2 · TkA05G030450 · TK1151

Mitochondrion0.110

Rank 3 · TkA05G030450 · TK1151

Cell membrane0.091

Rank 4 · TkA05G030450 · TK1151

Endoplasmic reticulum0.069

Rank 5 · TkA05G030450 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF00012HSP7010-112 aa

PF06723MreB_Mbl10-307 aa

PF14450FtsA12-91 aa

PF00012HSP70113-302 aa

PF01968Hydantoinase_A141-182 aa

PF27320YurS_helical148-153 aa

PF14450FtsA167-194 aa

PF09373PMBR236-245 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA05G030450	`PF00012`	HSP70	10	112	1.3e-128	430.6
TkA05G030450	`PF06723`	MreB_Mbl	10	307	7.8e-15	55.3
TkA05G030450	`PF14450`	FtsA	12	91	0.016	16.3
TkA05G030450	`PF00012`	HSP70	113	302	1.3e-128	430.6
TkA05G030450	`PF01968`	Hydantoinase_A	141	182	0.0016	18.5
TkA05G030450	`PF27320`	YurS_helical	148	153	1.5	9.8
TkA05G030450	`PF14450`	FtsA	167	194	0.016	16.3
TkA05G030450	`PF09373`	PMBR	236	245	0.16	12.8
TkA05G030450	`PF00012`	HSP70	299	376	1.3e-128	430.6
TkA05G030450	`PF09373`	PMBR	327	346	0.16	12.8
TkA05G030450	`PF27320`	YurS_helical	328	356	1.5	9.8

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

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Protein	Organism	Description	Identity	Database	Confidence
`Q9LHA8`	Arabidopsis thaliana	sp\|Q9LHA8\|HS704_ARATH Heat shock 70 kDa protein 4	41.700%	Swiss-Prot	Medium
`P22953`	Arabidopsis thaliana	sp\|P22953\|HS701_ARATH Heat shock 70 kDa protein 1	58.500%	Swiss-Prot	High
`O65719`	Arabidopsis thaliana	sp\|O65719\|HSP7C_ARATH Heat shock 70 kDa protein 3	58.500%	Swiss-Prot	High

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