TkA02G598370 | RubberDandelionOmics

Gene overview

TkA02G598370

Reference: TK1151 Chr: Chr02 Coordinates: 154264928-154265788 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

861 bp · TkA02G598370|TK1151|cDNA

ATGAGAGAGGATATAAAAAGCTTTAACATCGGTGGTATGGGGTGTAGTGCGAGTGCTTTAGCCGTTGACATGGCACATAACCTTTTGAAAGTTCACAAGAACTCTAACGCTTTAATTCTTTGTCCAGAAAATTTATCAAACGGTTGGTATGCAGGAAAAGACCGGTCGATGATGATCCTAAACTGCCTCTTCCGATCAGGTAGTGCAGCGGTTCTGATCTCCAACAAGAAATCCGCCAAAAATATATCCAAATACAGATT...

CDS

Download CDS FASTA

861 bp · TkA02G598370|TK1151|CDS

ATGAGAGAGGATATAAAAAGCTTTAACATCGGTGGTATGGGGTGTAGTGCGAGTGCTTTAGCCGTTGACATGGCACATAACCTTTTGAAAGTTCACAAGAACTCTAACGCTTTAATTCTTTGTCCAGAAAATTTATCAAACGGTTGGTATGCAGGAAAAGACCGGTCGATGATGATCCTAAACTGCCTCTTCCGATCAGGTAGTGCAGCGGTTCTGATCTCCAACAAGAAATCCGCCAAAAATATATCCAAATACAGATT...

Protein

Download Protein FASTA

286 aa · TkA02G598370|TK1151|PROTEIN

MREDIKSFNIGGMGCSASALAVDMAHNLLKVHKNSNALILCPENLSNGWYAGKDRSMMILNCLFRSGSAAVLISNKKSAKNISKYRLLYNLRTLGSFDDVAYNSAIREEDSKGNIGFTLKKDVLHIAGELIRSNFQVLGSAILPLEEKIRYGFSFIRKKFLDKSTELYVPNFRKVIQHYCLPTSGKAAVIMEIGRKMKLKEEEVDAALMTLHRFGNQLSSSLWYELSYMEGKERVKEGERVLQLGMGRGPKCISLVWECN...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

ID Mapping

Input ID	`TkA02G598370`
TK1151 ID	TkA02G598370
OH-1004 ID	LXL04_011997
Relationship / confidence	Multi Source To Oh1004 / Complex relationship
Protein identity (%)	93.000
Protein coverage (%)	TK1151 100.000 / OH-1004 60.127 Coverage and evidence Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.
Source version	TK1151 / GWHBCHF00000000

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SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene ID TkA02G598370

Location Chr02:154264928-154265788 (+)

Description Similar to KCS5: 3-ketoacyl-CoA synthase 5

Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene ID	Possible function	Papers / DOI
`At1g25450`	Mediates mostly the synthesis of very-long-chain fatty acids (VLCFAs) from 26 to 30 carbons in length.	Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides.2004 · DOI: 10.1073/pnas.0404600101
`At1g01120`	Contributes to cuticular wax and suberin biosynthesis.	KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.1999 · DOI: 10.1046/j.1365-313x.1999.00352.x Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides.2004 · DOI: 10.1073/pnas.0404600101 Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.2006 · DOI: 10.1016/j.bbrc.2006.05.162
`At4g34520`	Contributes to fatty acids elongation and stockage in developing seeds.	Engineering and mechanistic studies of the Arabidopsis FAE1 beta-ketoacyl-CoA synthase, FAE1 KCS.2002 · DOI: 10.1046/j.1432-1033.2002.03039.x Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides.2004 · DOI: 10.1073/pnas.0404600101 Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.2006 · DOI: 10.1016/j.bbrc.2006.05.162 Natural variation in seed very long chain fatty acid content is controlled by a new isoform of KCS18 in Arabidopsis thaliana.2012 · DOI: 10.1371/journal.pone.0049261 Directed tagging of the Arabidopsis FATTY ACID ELONGATION1 (FAE1) gene with the maize transposon activator.1995 · DOI: 10.1105/tpc.7.3.309 Very-long-chain fatty acid biosynthesis is controlled through the expression and specificity of the condensing enzyme.1997 · DOI: 10.1046/j.1365-313x.1997.12010121.x
`At1g19440`	3-ketoacyl-CoA synthase 4.	No verified direct reference in this release
`At1g68530`	Contributes to cuticular wax and suberin biosynthesis.	CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme.1999 · DOI: 10.1105/tpc.11.5.825 Alterations in CER6, a gene identical to CUT1, differentially affect long-chain lipid content on the surface of pollen and stems.2000 · DOI: 10.1105/tpc.12.10.2001

Rice

No hit for this species in the current source table.

Functional annotation source

View annotation sources

Functional annotation source: OH1004 · LXL04_011997 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)

GO:0000038 very long-chain fatty acid metabolic process Biological Process

GO:0006633 fatty acid biosynthetic process Biological Process

GO:0009409 response to cold Biological Process

GO:0009416 response to light stimulus Biological Process

GO:0009826 unidimensional cell growth Biological Process

GO:0010025 wax biosynthetic process Biological Process

GO:0030497 fatty acid elongation Biological Process

GO:0048868 pollen tube development Biological Process

GO:0160062 cutin-based cuticle development Biological Process

GO:0005737 cytoplasm Cellular Component

GO:0005739 mitochondrion Cellular Component

GO:0005783 endoplasmic reticulum Cellular Component

KEGG gene cross-reference

ath:AT1G19440

ath:AT1G25450

ath:AT1G68530

ath:AT2G16280

ath:AT4G34510

These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

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Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.693

Rank 1 · TkA02G598370 · TK1151

Peroxisome0.073

Rank 2 · TkA02G598370 · TK1151

Cytoplasm0.067

Rank 3 · TkA02G598370 · TK1151

Mitochondrion0.064

Rank 4 · TkA02G598370 · TK1151

Cell membrane0.053

Rank 5 · TkA02G598370 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF08392FAE1_CUT1_RppA1-159 aa

PF08541ACP_syn_III_C11-38 aa

PF08545ACP_syn_III14-85 aa

PF21147AMPK_alpha_AID120-131 aa

PF08392FAE1_CUT1_RppA165-192 aa

PF08541ACP_syn_III_C180-258 aa

PF02797Chal_sti_synt_C184-240 aa

PF21147AMPK_alpha_AID188-210 aa

Gene ID	Domain ID	Domain Name	Start aa	End aa	E-value	Score
TkA02G598370	`PF08392`	FAE1_CUT1_RppA	1	159	3e-59	201.4
TkA02G598370	`PF08541`	ACP_syn_III_C	11	38	4.5e-07	30.6
TkA02G598370	`PF08545`	ACP_syn_III	14	85	1.2e-05	25.8
TkA02G598370	`PF21147`	AMPK_alpha_AID	120	131	0.073	13.6
TkA02G598370	`PF08392`	FAE1_CUT1_RppA	165	192	3e-59	201.4
TkA02G598370	`PF08541`	ACP_syn_III_C	180	258	4.5e-07	30.6
TkA02G598370	`PF02797`	Chal_sti_synt_C	184	240	0.011	16.4
TkA02G598370	`PF21147`	AMPK_alpha_AID	188	210	0.073	13.6

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

Protein	Organism	Description	Identity	Database	Confidence
`Q9C6L5`	Arabidopsis thaliana	sp\|Q9C6L5\|KCS5_ARATH 3-ketoacyl-CoA synthase 5	44.300%	Swiss-Prot	Medium
`Q9MAM3`	Arabidopsis thaliana	sp\|Q9MAM3\|KCS1_ARATH 3-ketoacyl-CoA synthase 1	43.600%	Swiss-Prot	Medium
`Q38860`	Arabidopsis thaliana	sp\|Q38860\|KCS18_ARATH 3-ketoacyl-CoA synthase 18	46.100%	Swiss-Prot	Medium
`Q9LN49`	Arabidopsis thaliana	sp\|Q9LN49\|KCS4_ARATH 3-ketoacyl-CoA synthase 4	44.800%	Swiss-Prot	Medium
`Q9XF43`	Arabidopsis thaliana	sp\|Q9XF43\|KCS6_ARATH 3-ketoacyl-CoA synthase 6	44.000%	Swiss-Prot	Medium

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