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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp
Examples TkA01G624900 LXL04_000258

Gene overview

TkA02G405980
Reference: TK1151 Chr: Chr02 Coordinates: 103170748-103174664 Strand: - Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

Download cDNA FASTA

2225 bp · TkA02G405980|TK1151|cDNA

TTTTCGATTTTGCGTCTTTTACAAGGAAAAACTGAAAATACGTTAAGTTGAGTTCCCAACAACCTGGGGGCCCACTCCGAAGCATCTTCTGGTTGCATTTGGGTGTCCCGGCGCCAATTTCCGGCTACCATCGTCGCATTCTCCGTCTTCAAAGCCTAAAGGATTCGCCGATCTTCCAAACCGACAGCACCATACTCCGACACCGTTTTCTCTCTCTAACTTCTTCTCTTTTGATCTTGAGAGAGAAAGTGGAGAGAGAG...

CDS

Download CDS FASTA

1791 bp · TkA02G405980|TK1151|CDS

ATGGCGATTGATGACGACCAGTCCAAAACCTGCGTCGTCCTCGGAGGCAGAAGCTTCATTGGAAGATGTCTCGTCGCCAGGCTATTGAAACTAGGTAATTGGATCGTACGAGTTGCCGATTCCGCTCAGACCCTCCAACTCGATCCTTCCGAGTCCAAGCACGACTCGCCTCTTAACCGTGCTCTCTCCACTGGTCGTGCTTCCTATGCGCACGTTGATGTTCGCCACAAAAGTACAATCATTAACGCTATTGAAGGTTC...

Protein

Download Protein FASTA

596 aa · TkA02G405980|TK1151|PROTEIN

MAIDDDQSKTCVVLGGRSFIGRCLVARLLKLGNWIVRVADSAQTLQLDPSESKHDSPLNRALSTGRASYAHVDVRHKSTIINAIEGSEVVFYIDEIDSCNHDFHLGYSIIVQGAKNVINACRRCKVHRLIYNSTADVVIDKSHDICSGNETLLYSSKFKNLYSELKAQAEAFVLLANDIDGLLTCVLRPSNVFGPGDKILLPALIEVAQSGWAKFIIGSDQTISDFTYVENVAHALICAETALSSHMLIVSGRVFFITNF...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDTkA02G405980
TK1151 IDTkA02G405980
OH-1004 IDLXL04_014664
Relationship / confidenceRbh High Identity Coverage Synteny / Strict
Protein identity (%)95.500
Protein coverage (%)TK1151 100.000 / OH-1004 100.000
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionTK1151 / GWHBCHF00000000
Open Full ID Mapping
SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDTkA02G405980
LocationChr02:103170748-103174664 (-)
DescriptionSimilar to 3BETAHSD/D3: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At2g43420 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3. No verified direct reference in this release
At2g26260 3beta-hydroxysteroid-dehydrogenase/decarboxylase involved in sterol synthesis.
Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.2006 · DOI: 10.1074/jbc.m604431200
Overexpression of 3β-hydroxysteroid dehydrogenases/C-4 decarboxylases causes growth defects possibly due to abnormal auxin transport in Arabidopsis.2012 · DOI: 10.1007/s10059-012-0102-6
At1g47290 3beta-hydroxysteroid-dehydrogenase/decarboxylase involved in sterol synthesis.
Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.2006 · DOI: 10.1074/jbc.m604431200
Overexpression of 3β-hydroxysteroid dehydrogenases/C-4 decarboxylases causes growth defects possibly due to abnormal auxin transport in Arabidopsis.2012 · DOI: 10.1007/s10059-012-0102-6

Rice

No hit for this species in the current source table.

Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_014664 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)
GO:0006695 cholesterol biosynthetic process Biological Process
GO:0007224 smoothened signaling pathway Biological Process
GO:0008203 cholesterol metabolic process Biological Process
GO:0016126 sterol biosynthetic process Biological Process
GO:0033489 cholesterol biosynthetic process via desmosterol Biological Process
GO:0033490 cholesterol biosynthetic process via lathosterol Biological Process
GO:0036197 zymosterol biosynthetic process Biological Process
GO:0060918 auxin transport Biological Process
GO:0099402 plant organ development Biological Process
GO:0005783 endoplasmic reticulum Cellular Component
GO:0005789 endoplasmic reticulum membrane Cellular Component
GO:0005811 lipid droplet Cellular Component
KEGG gene cross-reference
ath:AT1G47290
ath:AT2G26260
ath:AT2G43420
bta:616694
rno:309262
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.
Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene
Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.358
Rank 1 · TkA02G405980 · TK1151
Golgi apparatus0.178
Rank 2 · TkA02G405980 · TK1151
Cytoplasm0.142
Rank 3 · TkA02G405980 · TK1151
Nucleus0.135
Rank 4 · TkA02G405980 · TK1151
Cell membrane0.128
Rank 5 · TkA02G405980 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF05368NmrA8-135 aa
PF010733Beta_HSD12-286 aa
PF01370Epimerase12-241 aa
PF16363GDP_Man_Dehyd13-260 aa
PF02719Polysacc_synt_213-136 aa
PF07993NAD_binding_415-32 aa
PF13460NAD_binding_1020-171 aa
PF04321RmlD_sub_bind94-280 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
TkA02G405980PF05368NmrA81350.0414.2
TkA02G405980PF010733Beta_HSD122866e-67226.3
TkA02G405980PF01370Epimerase122411.3e-2281.1
TkA02G405980PF16363GDP_Man_Dehyd132601.7e-0525.2
TkA02G405980PF02719Polysacc_synt_2131360.003117.5
TkA02G405980PF07993NAD_binding_415321.2e-0628.6
TkA02G405980PF13460NAD_binding_10201710.0001722.2
TkA02G405980PF04321RmlD_sub_bind942804.5e-0523.4
TkA02G405980PF07993NAD_binding_41072151.2e-0628.6
TkA02G405980PF02453Reticulon2102914.3e-2898.9
TkA02G405980PF010733Beta_HSD2933236e-67226.3
TkA02G405980PF16363GDP_Man_Dehyd3243481.7e-0525.2
TkA02G405980PF04418DUF5433804061.79.3
TkA02G405980PF02453Reticulon3855514.3e-2898.9
TkA02G405980PF04418DUF5435065301.79.3

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
A9X4U2Arabidopsis thalianasp|A9X4U2|HSDD3_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 345.900%Swiss-ProtMedium
Q67ZE1Arabidopsis thalianasp|Q67ZE1|HSDD2_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 236.100%Swiss-ProtMedium
Q9FX01Arabidopsis thalianasp|Q9FX01|HSDD1_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 141.600%Swiss-ProtMedium

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