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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp
Examples TkA01G624900 LXL04_000258

Gene overview

TkA01G027660
Reference: TK1151 Chr: Chr01 Coordinates: 7096092-7100122 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

cDNA

Download cDNA FASTA

2036 bp · TkA01G027660|TK1151|cDNA

TTTAATTTATCGACTTTCGTCCTGTTTTTCTCCGATCTTCATCGCTGGATTCTTGAACTTTCGCCCCACCTTTTCCAGATATTCAAACCCTTATTCGGTCCATCTCGTCGTTGATATATCGAATTCGAATGATCGATGGCAAGCTTTAACGCATAGTTTAGGAATTTTTTGCTCCTATTAAACAAAATCAATTCCTGAAGTTGCATCATCGGGAGTTTCCTAACAGTGCTTACAGCAAAATGATGAAGCTGCAGACGTAT...

CDS

Download CDS FASTA

1590 bp · TkA01G027660|TK1151|CDS

ATGATGAAGCTGCAGACGTATGCTGGACTCAGTATAGTTGCCACACTGGTTGTTATCTATCATGCATTTAGTAGCCGAGGCCAATTTTACCCAGCAACAGTCTATCTATCTACATCCAAAGTCTGTCTAGTCCTTCTTCTCAACATGGGTTTGGTGATCATGTGCATTATGTGGCAGCTAACAAAAAAAATATTTCTTGGTTCTCTTCGAGAAGCAGAAATTGAGAGACTGAATGAGCAATCATGGCGGGAAGTTATGGA...

Protein

Download Protein FASTA

529 aa · TkA01G027660|TK1151|PROTEIN

MMKLQTYAGLSIVATLVVIYHAFSSRGQFYPATVYLSTSKVCLVLLLNMGLVIMCIMWQLTKKIFLGSLREAEIERLNEQSWREVMEILFAITIFRQDFSVMFLAMVTALLLIKSLHWLAQKRVEYIETTPTVPMLSHIRIVSFMGFLLLVDSLFLYNSVKYLIKTRQASVSLFFSFEYTILATTTISTFVKYVFYVTDMLMEGQWEKKAVYTFYLELIRDLLHLSLYLGFFLVIFVNYGVPLHLIRELYETFRNFKLRI...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDTkA01G027660
TK1151 IDTkA01G027660
OH-1004 IDLXL04_005652
Relationship / confidenceRbh High Identity Coverage Synteny / Strict
Protein identity (%)97.400
Protein coverage (%)TK1151 100.000 / OH-1004 100.000
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionTK1151 / GWHBCHF00000000
Open Full ID Mapping
SNP / Indel variants and carrier samplesCRA009020 · TK1151

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDTkA01G027660
LocationChr01:7096092-7100122 (+)
DescriptionSimilar to HRD1A: ERAD-associated E3 ubiquitin-protein ligase HRD1A
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At3g16090 Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD). No verified direct reference in this release
At1g65040 Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD). No verified direct reference in this release

Rice

Reference gene IDPossible functionPapers / DOI
Os06g0301000 Probable component of the HRD1 ubiquitin ligase complex that mediates the rapid degradation of misfolded endoplasmic reticulum (ER) proteins, a process called ER-associated degradation (ERAD). No verified direct reference in this release
Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_005652 · GCA_047496595.1_OSU_TarKok_2.0. These OH1004 annotations are retrieved through ID mapping; the Arabidopsis/rice table below uses protein alignments from the query reference.

GO annotations (OH1004 source)
GO:0006511 ubiquitin-dependent protein catabolic process Biological Process
GO:0016567 protein ubiquitination Biological Process
GO:0030970 retrograde protein transport, ER to cytosol Biological Process
GO:0036503 ERAD pathway Biological Process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Biological Process
GO:0050821 protein stabilization Biological Process
GO:0070936 protein K48-linked ubiquitination Biological Process
GO:1904276 regulation of wax biosynthetic process Biological Process
GO:1904380 endoplasmic reticulum mannose trimming Biological Process
GO:0000836 Hrd1p ubiquitin ligase complex Cellular Component
GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex Cellular Component
GO:0005654 nucleoplasm Cellular Component
KEGG gene cross-reference
ath:AT1G65040
ath:AT3G16090
dosa:Os06g0301000
hsa:84447
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.
Open Annotation Module

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

View expression for this gene
Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Endoplasmic reticulum0.552
Rank 1 · TkA01G027660 · TK1151
Golgi apparatus0.225
Rank 2 · TkA01G027660 · TK1151
Nucleus0.142
Rank 3 · TkA01G027660 · TK1151
Cytoplasm0.119
Rank 4 · TkA01G027660 · TK1151
Cell membrane0.097
Rank 5 · TkA01G027660 · TK1151

LocPro · Direct prediction · Computational prediction, not experimental localization

Open Subcellular Module

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF25563TPR_SYVN1_N3-272 aa
PF12678zf-rbx1289-330 aa
PF13920zf-C3HC4_3290-331 aa
PF05605zf-Di19290-333 aa
PF13639zf-RING_2291-330 aa
PF17120zf-RING_16291-327 aa
PF29452FAR1_N291-337 aa
PF24921RING_XB3-XBAT31291-331 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
TkA01G027660PF25563TPR_SYVN1_N32722.5e-107359.1
TkA01G027660PF12678zf-rbx12893301.1e-0835.8
TkA01G027660PF13920zf-C3HC4_32903313.1e-0524.4
TkA01G027660PF05605zf-Di192903330.2212.5
TkA01G027660PF13639zf-RING_22913302.9e-1144.1
TkA01G027660PF17120zf-RING_162913270.03514.4
TkA01G027660PF29452FAR1_N2913370.3411.7
TkA01G027660PF24921RING_XB3-XBAT312913311.29.9
TkA01G027660PF22908PHD_NSD2913231.89.7
TkA01G027660PF26037zf-RING_DCST1_C2913304.08.2
TkA01G027660PF23413zf_RING_Vps8_fungal2912974.17.5
TkA01G027660PF00097zf-C3HC42923292.3e-0731.3
TkA01G027660PF13445zf-RING_UBOX2923271e-0629.3
TkA01G027660PF13923zf-C3HC4_22923294e-0627.2
TkA01G027660PF14634zf-RING_52923300.01116.4
TkA01G027660PF14447Prok-RING_42923310.07613.6

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
Q9LW77Arabidopsis thalianasp|Q9LW77|HRD1A_ARATH ERAD-associated E3 ubiquitin-protein ligase HRD1A72.900%Swiss-ProtHigh
Q6NPT7Arabidopsis thalianasp|Q6NPT7|HRD1B_ARATH ERAD-associated E3 ubiquitin-protein ligase HRD1B70.800%Swiss-ProtHigh
Q5Z880Oryza sativa subsp. japonicasp|Q5Z880|HRD1_ORYSJ ERAD-associated E3 ubiquitin-protein ligase HRD171.300%Swiss-ProtHigh

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