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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp

Gene overview

LXL04_026698
Reference: OH-1004 Chr: Chr06 Coordinates: 1553573-1558337 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

1797 bp · LXL04_026698|LXL04_026698|OH1004|cDNA

ATGAAGGTAATTGAGAAGATTTTGGAGTCTACGGCGGCCGGAGATGCCGGAAAGGTTGTGTTTTCCTTCGAATTCTTCCCTCCCAAGACGGAGGAAGGTGTCGAGAATCTGTTCGAAAGGATGGAGCGTATGGTAGCTCACAATCCTACATTTTGCGATATCACATGGGGTGCCGGTGGTACCACGGCGGACCTGACTTTGGAAATAGCAAGAAGGATGCAGAACATGGTGTGTGTGGAGACTATGATGCATTTGACGTG...

1797 bp · LXL04_026698|LXL04_026698|OH1004|CDS

ATGAAGGTAATTGAGAAGATTTTGGAGTCTACGGCGGCCGGAGATGCCGGAAAGGTTGTGTTTTCCTTCGAATTCTTCCCTCCCAAGACGGAGGAAGGTGTCGAGAATCTGTTCGAAAGGATGGAGCGTATGGTAGCTCACAATCCTACATTTTGCGATATCACATGGGGTGCCGGTGGTACCACGGCGGACCTGACTTTGGAAATAGCAAGAAGGATGCAGAACATGGTGTGTGTGGAGACTATGATGCATTTGACGTG...

598 aa · LXL04_026698|LXL04_026698|OH1004|PROTEIN

MKVIEKILESTAAGDAGKVVFSFEFFPPKTEEGVENLFERMERMVAHNPTFCDITWGAGGTTADLTLEIARRMQNMVCVETMMHLTCTNMPVEKIDHALETIKKDGIQNVLALRGDPPRGQDKFVQIQGGFACALDLVEHIRKSYDDYFGIAVAGYPEAHPEVIESNGLATPDAYQKDLAYLKKKVDAGADVIVTQLFYDVENFLKFVNDCRQIGITCPIVPGIMPINNYNGFIRMTGFCKTRIPSEITAALEPIKDNEE...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDLXL04_026698
Source versionOH-1004 / GCA_047496595.1_OSU_TarKok_2.0
SNP / Indel variants and carrier samplesCRA009020 · OH-1004

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDLXL04_026698
LocationChr06:1553573-1558337 (+)
DescriptionSimilar to Methylenetetrahydrofolate reductase 1
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At3g59970 The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10-methylenetetrahydrofolate to serine, sugars and starch. No verified direct reference in this release
At2g44160 The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10-methylenetetrahydrofolate to serine, sugars and starch. No verified direct reference in this release

Rice

Reference gene IDPossible functionPapers / DOI
Os03g0815200 The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10-methylenetetrahydrofolate to serine, sugars and starch. No verified direct reference in this release
Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_026698 · GCA_047496595.1_OSU_TarKok_2.0.

GO annotations (OH1004 source)
GO:0001666 response to hypoxia Biological Process
GO:0006555 methionine metabolic process Biological Process
GO:0009086 methionine biosynthetic process Biological Process
GO:0009410 response to xenobiotic stimulus Biological Process
GO:0033274 response to vitamin B2 Biological Process
GO:0035999 tetrahydrofolate interconversion Biological Process
GO:0043200 response to amino acid Biological Process
GO:0046500 S-adenosylmethionine metabolic process Biological Process
GO:0050667 homocysteine metabolic process Biological Process
GO:0051593 response to folic acid Biological Process
GO:0070555 response to interleukin-1 Biological Process
GO:0070828 heterochromatin organization Biological Process
KEGG gene cross-reference
ath:AT2G44160
ath:AT3G59970
hsa:4524
zma:118474709
zma:541794
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.732
Rank 1 · LXL04_026698 · OH-1004
Nucleus0.269
Rank 2 · LXL04_026698 · OH-1004
Cell membrane0.086
Rank 3 · LXL04_026698 · OH-1004
Mitochondrion0.078
Rank 4 · LXL04_026698 · OH-1004
Endoplasmic reticulum0.071
Rank 5 · LXL04_026698 · OH-1004

LocPro · Direct prediction · Computational prediction, not experimental localization

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF02219.24MTHFR15-304 aa
PF21895.2MTHFR_C313-592 aa
PF21897.2DUF6919394-496 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
LXL04_026698PF02219.24MTHFR153041.8e-121405.6
LXL04_026698PF21895.2MTHFR_C3135923.1e-88296.7
LXL04_026698PF21897.2DUF69193944969.1e-0936.4

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
Q9SE60Arabidopsis thalianaMethylenetetrahydrofolate reductase (NADH) 175.462%Swiss-Protstrong database homology
O80585Arabidopsis thalianaMethylenetetrahydrofolate reductase (NADH) 276.471%Swiss-Protstrong database homology
Q75HE6Oryza sativa subsp. japonicaProbable methylenetetrahydrofolate reductase (NADH)76.846%Swiss-Protstrong database homology

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