Gene Card
Gene overview
cDNA / CDS / Protein Sequences
1377 bp · LXL04_026494|LXL04_026494|OH1004|cDNA
ATGGCTCCTCAAAACGTTGGAATTCTCGCCATGGAAATCTACTTCCCTCCTACTTGTATCAAACAGGATACTCTAGAAAACTTTGATGGAGTCAGTAAAGGAAAATACACCATTGGACTCGGACAAGATTGCATGGCATTTTGCTCAGAGGTTGAAGATGTCATTTCCATGGGACTGACAGCTGTCACTTCACTACTCGAGAAGTATGAAATCGACCCAAAACAAATCGGTCGATTGGAAGTCGGGAGTGAAACCGTAAT...
1377 bp · LXL04_026494|LXL04_026494|OH1004|CDS
ATGGCTCCTCAAAACGTTGGAATTCTCGCCATGGAAATCTACTTCCCTCCTACTTGTATCAAACAGGATACTCTAGAAAACTTTGATGGAGTCAGTAAAGGAAAATACACCATTGGACTCGGACAAGATTGCATGGCATTTTGCTCAGAGGTTGAAGATGTCATTTCCATGGGACTGACAGCTGTCACTTCACTACTCGAGAAGTATGAAATCGACCCAAAACAAATCGGTCGATTGGAAGTCGGGAGTGAAACCGTAAT...
Protein
Download Protein FASTA458 aa · LXL04_026494|LXL04_026494|OH1004|PROTEIN
MAPQNVGILAMEIYFPPTCIKQDTLENFDGVSKGKYTIGLGQDCMAFCSEVEDVISMGLTAVTSLLEKYEIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEDCGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVSTDSAVYAEGAARPTGGAGAVAMLIGPDAPIAFESKFRASHMEHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYKRYCQKYEKIQGKEFSMADADYFVFHSPYNKLVQKSFA...
Flanking Sequence Download
Sequence orientation and download details
Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.
ID Mapping
| Input ID | LXL04_026494 |
|---|---|
| TK1151 ID | TkA06G008820 |
| OH-1004 ID | LXL04_026494 |
| Relationship / confidence | Rbh High Identity Coverage Synteny / Strict |
| Protein identity (%) | 100.000 |
| Protein coverage (%) | TK1151 100.000 / OH-1004 100.000Coverage and evidenceCoverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation. |
| Source version | OH-1004 / GCA_047496595.1_OSU_TarKok_2.0 |
SNP / Indel variants and carrier samplesCRA009020 · OH-1004
Expand to load variant records for this gene.
Basic Information and Functional Annotation
| Gene ID | LXL04_026494 | ||||||
|---|---|---|---|---|---|---|---|
| Location | Chr05:127347496-127350406 (+) | ||||||
| Description | Similar to HMGS: Hydroxymethylglutaryl-CoA synthase | ||||||
| Arabidopsis / Rice Reference Genes and Papers |
Download references for this gene Arabidopsis
RiceNo hit for this species in the current source table. | ||||||
| Functional annotation source | View annotation sourcesFunctional annotation source: OH1004 · | ||||||
| GO annotations (OH1004 source) | GO:0006084 acetyl-CoA metabolic process Biological Process GO:0006629 lipid metabolic process Biological Process GO:0006695 cholesterol biosynthetic process Biological Process GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway Biological Process GO:0016126 sterol biosynthetic process Biological Process GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway Biological Process GO:0033386 geranylgeranyl diphosphate biosynthetic process Biological Process GO:0033489 cholesterol biosynthetic process via desmosterol Biological Process GO:0033490 cholesterol biosynthetic process via lathosterol Biological Process GO:0036197 zymosterol biosynthetic process Biological Process GO:0044351 macropinocytosis Biological Process GO:0005654 nucleoplasm Cellular Component | ||||||
| KEGG gene cross-reference | ath:AT4G11820 ddi:DDB_G0288461 hsa:3157 pon:100174584 These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene. |
Gene expression
View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.
Data sources and gene correspondence
Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.
Subcellular Localization Top 5
Computational predictions or homology annotations below do not replace localization experiments.
LocPro · Direct prediction · Computational prediction, not experimental localization
Predicted Functional Domains
Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.
PF01154.23HMG_CoA_synt_N3-175 aaPF08540.17HMG_CoA_synt_C176-450 aa| Gene ID | Domain ID | Domain Name | Start aa | End aa | E-value | Score |
|---|---|---|---|---|---|---|
| LXL04_026494 | PF01154.23 | HMG_CoA_synt_N | 3 | 175 | 1e-84 | 283.4 |
| LXL04_026494 | PF08540.17 | HMG_CoA_synt_C | 176 | 450 | 3.9e-110 | 368.6 |
Arabidopsis / Rice Protein Homology
Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.
| Protein | Organism | Description | Identity | Database | Confidence |
|---|---|---|---|---|---|
P54873 | Arabidopsis thaliana | Hydroxymethylglutaryl-CoA synthase | 76.035% | Swiss-Prot | strong database homology |