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Gene Card

Enter a TK1151 or OH-1004 gene ID to view sequences, annotations and analyses in the corresponding reference genome.
Flanking length, max 10000 bp

Gene overview

LXL04_026494
Reference: OH-1004 Chr: Chr05 Coordinates: 127347496-127350406 Strand: + Type: protein_coding

cDNA / CDS / Protein Sequences

Available sequence downloads CDS FASTA Protein FASTA cDNA FASTA

1377 bp · LXL04_026494|LXL04_026494|OH1004|cDNA

ATGGCTCCTCAAAACGTTGGAATTCTCGCCATGGAAATCTACTTCCCTCCTACTTGTATCAAACAGGATACTCTAGAAAACTTTGATGGAGTCAGTAAAGGAAAATACACCATTGGACTCGGACAAGATTGCATGGCATTTTGCTCAGAGGTTGAAGATGTCATTTCCATGGGACTGACAGCTGTCACTTCACTACTCGAGAAGTATGAAATCGACCCAAAACAAATCGGTCGATTGGAAGTCGGGAGTGAAACCGTAAT...

1377 bp · LXL04_026494|LXL04_026494|OH1004|CDS

ATGGCTCCTCAAAACGTTGGAATTCTCGCCATGGAAATCTACTTCCCTCCTACTTGTATCAAACAGGATACTCTAGAAAACTTTGATGGAGTCAGTAAAGGAAAATACACCATTGGACTCGGACAAGATTGCATGGCATTTTGCTCAGAGGTTGAAGATGTCATTTCCATGGGACTGACAGCTGTCACTTCACTACTCGAGAAGTATGAAATCGACCCAAAACAAATCGGTCGATTGGAAGTCGGGAGTGAAACCGTAAT...

458 aa · LXL04_026494|LXL04_026494|OH1004|PROTEIN

MAPQNVGILAMEIYFPPTCIKQDTLENFDGVSKGKYTIGLGQDCMAFCSEVEDVISMGLTAVTSLLEKYEIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEDCGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVSTDSAVYAEGAARPTGGAGAVAMLIGPDAPIAFESKFRASHMEHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYKRYCQKYEKIQGKEFSMADADYFVFHSPYNKLVQKSFA...

Flanking Sequence Download

Sequence orientation and download details

Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.

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ID Mapping

Input IDLXL04_026494
TK1151 IDTkA06G008820
OH-1004 IDLXL04_026494
Relationship / confidenceRbh High Identity Coverage Synteny / Strict
Protein identity (%)100.000
Protein coverage (%)TK1151 100.000 / OH-1004 100.000
Coverage and evidence

Coverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation.

Source versionOH-1004 / GCA_047496595.1_OSU_TarKok_2.0
SNP / Indel variants and carrier samplesCRA009020 · OH-1004

Expand to load variant records for this gene.

Basic Information and Functional Annotation

Gene IDLXL04_026494
LocationChr05:127347496-127350406 (+)
DescriptionSimilar to HMGS: Hydroxymethylglutaryl-CoA synthase
Arabidopsis / Rice Reference Genes and Papers

Download references for this gene

Arabidopsis

Reference gene IDPossible functionPapers / DOI
At4g11820 This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.

Rice

No hit for this species in the current source table.

Functional annotation source
View annotation sources

Functional annotation source: OH1004 · LXL04_026494 · GCA_047496595.1_OSU_TarKok_2.0.

GO annotations (OH1004 source)
GO:0006084 acetyl-CoA metabolic process Biological Process
GO:0006629 lipid metabolic process Biological Process
GO:0006695 cholesterol biosynthetic process Biological Process
GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway Biological Process
GO:0016126 sterol biosynthetic process Biological Process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway Biological Process
GO:0033386 geranylgeranyl diphosphate biosynthetic process Biological Process
GO:0033489 cholesterol biosynthetic process via desmosterol Biological Process
GO:0033490 cholesterol biosynthetic process via lathosterol Biological Process
GO:0036197 zymosterol biosynthetic process Biological Process
GO:0044351 macropinocytosis Biological Process
GO:0005654 nucleoplasm Cellular Component
KEGG gene cross-reference
ath:AT4G11820
ddi:DDB_G0288461
hsa:3157
pon:100174584
These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene.

Gene expression

View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.

Data sources and gene correspondence

Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.

Subcellular Localization Top 5

Computational predictions or homology annotations below do not replace localization experiments.

Cytoplasm0.741
Rank 1 · LXL04_026494 · OH-1004
Nucleus0.273
Rank 2 · LXL04_026494 · OH-1004
Endoplasmic reticulum0.102
Rank 3 · LXL04_026494 · OH-1004
Mitochondrion0.074
Rank 4 · LXL04_026494 · OH-1004
Cell membrane0.061
Rank 5 · LXL04_026494 · OH-1004

LocPro · Direct prediction · Computational prediction, not experimental localization

Predicted Functional Domains

Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.

PF01154.23HMG_CoA_synt_N3-175 aa
PF08540.17HMG_CoA_synt_C176-450 aa
Gene IDDomain IDDomain NameStart aaEnd aaE-valueScore
LXL04_026494PF01154.23HMG_CoA_synt_N31751e-84283.4
LXL04_026494PF08540.17HMG_CoA_synt_C1764503.9e-110368.6

Arabidopsis / Rice Protein Homology

Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.

Download current result

ProteinOrganismDescriptionIdentityDatabaseConfidence
P54873Arabidopsis thalianaHydroxymethylglutaryl-CoA synthase76.035%Swiss-Protstrong database homology

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