Gene Card
Gene overview
cDNA / CDS / Protein Sequences
576 bp · TkA08G296340|TK1151|cDNA
ATGTGGGCGACGGCGACGATTCTAATCCCCATTAAAGGGCGACCGGCGAATTACAACGTCATGTTTCAATTAGCGGACTCCGAAGGAACGCCGCTCGGTGCTTCCATATATCTTCCCCAAAGCATTGGCCCCAAGGAGCTTCAACAGATGGTTAACAAGTTGCTCAACAATGAGGAAAGGCTACCATACGCCTTTTATATATCCGATCAAGAGCTTGTTATACAACTAGGAGATTATTTGCAGAAGAACAAAGTTTCTGT...
576 bp · TkA08G296340|TK1151|CDS
ATGTGGGCGACGGCGACGATTCTAATCCCCATTAAAGGGCGACCGGCGAATTACAACGTCATGTTTCAATTAGCGGACTCCGAAGGAACGCCGCTCGGTGCTTCCATATATCTTCCCCAAAGCATTGGCCCCAAGGAGCTTCAACAGATGGTTAACAAGTTGCTCAACAATGAGGAAAGGCTACCATACGCCTTTTATATATCCGATCAAGAGCTTGTTATACAACTAGGAGATTATTTGCAGAAGAACAAAGTTTCTGT...
Protein
Download Protein FASTA191 aa · TkA08G296340|TK1151|PROTEIN
MWATATILIPIKGRPANYNVMFQLADSEGTPLGASIYLPQSIGPKELQQMVNKLLNNEERLPYAFYISDQELVIQLGDYLQKNKVSVEKVVTIVYRPRAVLRIRPVTRCSSTIAGHTEAVLSVVFSLDGQQLASGSGDTTVRLWDLNTQTPLFTCTWHKNWVLCVSWSPDGKHLVSGSKSGEIQICKIRSL
Flanking Sequence Download
Sequence orientation and download details
Upstream/downstream are capped at 10000 bp per side. Negative-strand genes are reverse-complemented so the final FASTA follows transcriptional 5′→3′ orientation.
ID Mapping
| Input ID | TkA08G296340 |
|---|---|
| TK1151 ID | TkA08G296340 |
| OH-1004 ID | LXL04_010891 |
| Relationship / confidence | Rbh Below Probable Coverage Or Synteny Threshold / Review |
| Protein identity (%) | 93.600 |
| Protein coverage (%) | TK1151 73.298 / OH-1004 29.167Coverage and evidenceCoverage is the aligned span of the best-scoring HSP divided by representative protein length. A homolog match does not establish functional validation. |
| Source version | TK1151 / GWHBCHF00000000 |
SNP / Indel variants and carrier samplesCRA009020 · TK1151
Expand to load variant records for this gene.
Basic Information and Functional Annotation
| Gene ID | TkA08G296340 | ||||||
|---|---|---|---|---|---|---|---|
| Location | Chr08:76812840-76813864 (+) | ||||||
| Description | Similar to NLE1: Notchless protein homolog | ||||||
| Arabidopsis / Rice Reference Genes and Papers |
Download references for this gene Arabidopsis
RiceNo hit for this species in the current source table. | ||||||
| Functional annotation source | View annotation sourcesFunctional annotation source: OH1004 · | ||||||
| GO annotations (OH1004 source) | GO:0000027 ribosomal large subunit assembly Biological Process GO:0007219 Notch signaling pathway Biological Process GO:0008593 regulation of Notch signaling pathway Biological Process GO:0009553 embryo sac development Biological Process GO:0042273 ribosomal large subunit biogenesis Biological Process GO:0045930 negative regulation of mitotic cell cycle Biological Process GO:0061484 hematopoietic stem cell homeostasis Biological Process GO:0090263 positive regulation of canonical Wnt signaling pathway Biological Process GO:0005634 nucleus Cellular Component GO:0005654 nucleoplasm Cellular Component GO:0005730 nucleolus Cellular Component GO:0080008 Cul4-RING E3 ubiquitin ligase complex Cellular Component | ||||||
| KEGG gene cross-reference | ath:AT5G52820 hsa:54475 mmu:217011 pon:100171489 These KEGG gene identifiers are linked through homologous proteins; they do not establish pathway function for this gene. |
Gene expression
View expression in different studies, tissues and treatments. Results are presented separately by study and measurement unit.
Data sources and gene correspondence
Expression data come from public transcriptome studies. Reference genomes, sample metadata and measurement units are shown with the results. Ambiguous cross-reference correspondences do not select an expression record automatically; missing values do not mean zero expression.
Subcellular Localization Top 5
Computational predictions or homology annotations below do not replace localization experiments.
LocPro · Direct prediction · Computational prediction, not experimental localization
Predicted Functional Domains
Domain results are from Pfam-A/HMMER; positions are amino-acid coordinates on the protein sequence.
PF22007DUF693014-90 aaPF08154NLE23-80 aaPF25047Beta-prop_TEP1_2nd87-188 aaPF25460Beta-prop_Aladin101-182 aaPF25174Beta-prop_THOC3107-189 aaPF25391WD40_Gbeta107-189 aaPF00400WD40108-145 aaPF25175Beta-prop_WDR5108-189 aa| Gene ID | Domain ID | Domain Name | Start aa | End aa | E-value | Score |
|---|---|---|---|---|---|---|
| TkA08G296340 | PF22007 | DUF6930 | 14 | 90 | 0.087 | 13.8 |
| TkA08G296340 | PF08154 | NLE | 23 | 80 | 1.3e-13 | 51.9 |
| TkA08G296340 | PF25047 | Beta-prop_TEP1_2nd | 87 | 188 | 4.8e-14 | 52.9 |
| TkA08G296340 | PF25460 | Beta-prop_Aladin | 101 | 182 | 3.5e-06 | 27.1 |
| TkA08G296340 | PF25174 | Beta-prop_THOC3 | 107 | 189 | 1.4e-19 | 70.9 |
| TkA08G296340 | PF25391 | WD40_Gbeta | 107 | 189 | 3e-09 | 37.1 |
| TkA08G296340 | PF00400 | WD40 | 108 | 145 | 4.4e-20 | 72.0 |
| TkA08G296340 | PF25175 | Beta-prop_WDR5 | 108 | 189 | 7.9e-18 | 65.5 |
| TkA08G296340 | PF24807 | WD40_CDC20-Fz | 108 | 183 | 3.8e-13 | 50.1 |
| TkA08G296340 | PF24814 | WD40_Prp19 | 108 | 188 | 7.6e-11 | 42.3 |
| TkA08G296340 | PF24782 | WD40_MABP1-WDR62_2nd | 108 | 146 | 1.8e-09 | 37.7 |
| TkA08G296340 | PF23756 | Beta-prop_HPS5 | 108 | 189 | 0.00019 | 21.5 |
| TkA08G296340 | PF23419 | WD40_RFWD3 | 108 | 190 | 0.055 | 13.5 |
| TkA08G296340 | PF25173 | Beta-prop_WDR3_1st | 109 | 184 | 2e-16 | 61.0 |
| TkA08G296340 | PF23869 | Beta-prop_WDR75_1st | 109 | 146 | 8.8e-05 | 22.7 |
| TkA08G296340 | PF24506 | KNTC1_N | 109 | 151 | 0.06 | 13.3 |
Arabidopsis / Rice Protein Homology
Only Arabidopsis and rice are shown. Swiss-Prot entries are reviewed; TrEMBL entries are supplementary sequence candidates. Similarity is not experimental validation.
| Protein | Organism | Description | Identity | Database | Confidence |
|---|---|---|---|---|---|
Q9FLX9 | Arabidopsis thaliana | sp|Q9FLX9|NLE1_ARATH Notchless protein homolog | 69.100% | Swiss-Prot | High |