Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

5 candidates match the current filter; 10 are shown per page (page 1 of 1). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_008538
TK1151: -
OH-1004: LXL04_008538
Rubber biosynthesis
Cis-prenyltransferase branch
Low
score 2
FunctionExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:102148073-102150399
-
lxl04_008538 similar to cpt1: coleoptile phototropism protein 1 (oryza sativa subsp. japonica ox=39947)
LXL04_013139
TK1151: -
OH-1004: LXL04_013139
Rubber biosynthesis
Cis-prenyltransferase branch
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:24689434-24689868
+
go:0050267 rubber cis-polyprenylcistransferase activity molecular_function
TkA02G466190
TK1151: TkA02G466190;TkA02G466270
OH-1004: LXL04_013887
Rubber biosynthesis
Cis-prenyltransferase branch
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:37511054-37514799
-
go:0050267 rubber cis-polyprenylcistransferase activity molecular_function
TkA05G048860
TK1151: TkA05G048860
OH-1004: LXL04_019393
Rubber biosynthesis
Cis-prenyltransferase branch
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:30311697-30312670
+
go:0050267 rubber cis-polyprenylcistransferase activity molecular_function
TkA02G514830
TK1151: TkA02G514830;TkA05G057980
OH-1004: LXL04_019522
Rubber biosynthesis
Cis-prenyltransferase branch
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:32936688-32939074
+
go:0050267 rubber cis-polyprenylcistransferase activity molecular_function

LXL04_008538

Rubber biosynthesisCis-prenyltransferase branchLow · score 2
Source ID-
LocationCM104800.1:102148073-102150399 -
EvidenceFunctionExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencelxl04_008538 similar to cpt1: coleoptile phototropism protein 1 (oryza sativa subsp. japonica ox=39947)

LXL04_013139

Rubber biosynthesisCis-prenyltransferase branchLow · score 2
Source ID-
LocationCM104801.1:24689434-24689868 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0050267 rubber cis-polyprenylcistransferase activity molecular_function

TkA02G466190

Rubber biosynthesisCis-prenyltransferase branchLow · score 2
Source IDTkA02G466190;TkA02G466270
LocationCM104801.1:37511054-37514799 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0050267 rubber cis-polyprenylcistransferase activity molecular_function

TkA05G048860

Rubber biosynthesisCis-prenyltransferase branchLow · score 2
Source IDTkA05G048860
LocationCM104802.1:30311697-30312670 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0050267 rubber cis-polyprenylcistransferase activity molecular_function

TkA02G514830

Rubber biosynthesisCis-prenyltransferase branchLow · score 2
Source IDTkA02G514830;TkA05G057980
LocationCM104802.1:32936688-32939074 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0050267 rubber cis-polyprenylcistransferase activity molecular_function

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.