Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 6 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA02G247560
TK1151: TkA02G247560;TkA04G108400
OH-1004: LXL04_035794
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:28917190-28919427
+
go:0006970 response to osmotic stress biological_process
TkA04G040380
TK1151: TkA04G040380
OH-1004: LXL04_036503
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:43541605-43543195
+
go:0006970 response to osmotic stress biological_process
LXL04_037072
TK1151: -
OH-1004: LXL04_037072
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:52574712-52575078
+
go:0006950 response to stress biological_process
TkA04G005750
TK1151: TkA04G005750;TkA04G006590
OH-1004: LXL04_037075
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:52709033-52709502
+
go:0006950 response to stress biological_process
TkA04G473400
TK1151: TkA04G473400
OH-1004: LXL04_038880
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104807.1:52395285-52395821
+
go:0006950 response to stress biological_process
TkA04G224110
TK1151: TkA04G224110
OH-1004: LXL04_039378
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPI JAJTUU010000010.1:5379552-5380505
+
go:0006950 response to stress biological_process
TkA01G594250
TK1151: TkA01G594250
OH-1004: LXL04_000681
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:12510590-12512452
+
go:0010102 lateral root morphogenesis biological_process
TkA01G580990
TK1151: TkA01G580990
OH-1004: LXL04_000847
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:15606983-15611177
-
go:0006979 response to oxidative stress biological_process
TkA01G565860
TK1151: TkA01G565860
OH-1004: LXL04_001030
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:18857882-18861159
+
go:0010053 root epidermal cell differentiation biological_process
TkA01G541420
TK1151: TkA01G541420;TkA02G345970
OH-1004: LXL04_001386
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:25351918-25353338
-
go:0009611 response to wounding biological_process

TkA02G247560

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA02G247560;TkA04G108400
LocationCM104806.1:28917190-28919427 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA04G040380

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA04G040380
LocationCM104806.1:43541605-43543195 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

LXL04_037072

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source ID-
LocationCM104806.1:52574712-52575078 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

TkA04G005750

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA04G005750;TkA04G006590
LocationCM104806.1:52709033-52709502 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

TkA04G473400

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA04G473400
LocationCM104807.1:52395285-52395821 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006950 response to stress biological_process

TkA04G224110

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA04G224110
LocationJAJTUU010000010.1:5379552-5380505 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0006950 response to stress biological_process

TkA01G594250

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G594250
LocationCM104799.1:12510590-12512452 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010102 lateral root morphogenesis biological_process

TkA01G580990

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G580990
LocationCM104799.1:15606983-15611177 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA01G565860

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G565860
LocationCM104799.1:18857882-18861159 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

TkA01G541420

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G541420;TkA02G345970
LocationCM104799.1:25351918-25353338 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.