Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 5 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA03G103720
TK1151: TkA03G103720
OH-1004: LXL04_007018
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:33846152-33847563
+
GO:0008299
TkA02G477400
TK1151: TkA02G477400;TkA03G108120
OH-1004: LXL04_007062
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:34968648-34978505
+
GO:0016740
TkA03G137290
TK1151: TkA03G137290
OH-1004: LXL04_007205
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:39506769-39513818
+
GO:0008299
LXL04_007243
TK1151: -
OH-1004: LXL04_007243
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:40904088-40904702
+
GO:0016114
TkA03G164130
TK1151: TkA03G164130;TkA03G169300
OH-1004: LXL04_007395
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:46575313-46577343
-
GO:0016114
TkA03G325630
TK1151: TkA03G325630
OH-1004: LXL04_007509
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:51008832-51011179
+
GO:0008299
TkA03G193790
TK1151: TkA03G193790
OH-1004: LXL04_007585
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:53197768-53205881
-
GO:0016740
TkA05G289620
TK1151: TkA05G289620
OH-1004: LXL04_007882
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:70233972-70237230
+
GO:0016740
TkA03G389990
TK1151: TkA03G389990
OH-1004: LXL04_008256
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:94984722-94987063
-
GO:0016114
TkA03G300890
TK1151: TkA03G300890
OH-1004: LXL04_008981
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:114849265-114851137
+
GO:0016740

TkA03G103720

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G103720
LocationCM104800.1:33846152-33847563 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA02G477400

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G477400;TkA03G108120
LocationCM104800.1:34968648-34978505 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA03G137290

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G137290
LocationCM104800.1:39506769-39513818 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

LXL04_007243

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:40904088-40904702 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G164130

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G164130;TkA03G169300
LocationCM104800.1:46575313-46577343 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G325630

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G325630
LocationCM104800.1:51008832-51011179 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA03G193790

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G193790
LocationCM104800.1:53197768-53205881 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA05G289620

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA05G289620
LocationCM104800.1:70233972-70237230 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G389990

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G389990
LocationCM104800.1:94984722-94987063 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G300890

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G300890
LocationCM104800.1:114849265-114851137 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.