Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

380 candidates match the current filter; 10 are shown per page (page 35 of 38). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_032798
TK1151: -
OH-1004: LXL04_032798
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:29441910-29443493
+
go:0016114 terpenoid biosynthetic process biological_process
TkA08G205390
TK1151: TkA08G205390
OH-1004: LXL04_032799
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:29447303-29455115
+
go:0016114 terpenoid biosynthetic process biological_process
TkAUNG042360
TK1151: TkAUNG042360;TkA05G423610;TkA07G019450;TkA08G206530
OH-1004: LXL04_032816
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:29717175-29719867
+
go:0016117 carotenoid biosynthetic process biological_process
TkA02G537400
TK1151: TkA02G537400;TkA04G085260;TkA08G208950
OH-1004: LXL04_032843
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:30377850-30378802
-
go:0016114 terpenoid biosynthetic process biological_process
LXL04_032846
TK1151: -
OH-1004: LXL04_032846
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:30421132-30421449
-
go:0016114 terpenoid biosynthetic process biological_process
LXL04_032847
TK1151: -
OH-1004: LXL04_032847
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:30426324-30430068
-
go:0016114 terpenoid biosynthetic process biological_process
TkA08G209260
TK1151: TkA08G209260
OH-1004: LXL04_032851
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:30474280-30474914
-
go:0016114 terpenoid biosynthetic process biological_process
TkA08G208960
TK1151: TkA08G208960;TkA08G209130
OH-1004: LXL04_032854
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:30565640-30566978
-
go:0016114 terpenoid biosynthetic process biological_process
TkA08G208680
TK1151: TkA08G208680;TkA08G208830;TkA08G209600
OH-1004: LXL04_032855
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:30589892-30590902
-
go:0016114 terpenoid biosynthetic process biological_process
LXL04_033183
TK1151: -
OH-1004: LXL04_033183
Terpenoid metabolism
Terpenoid metabolism
Low
score 2
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:37827726-37836466
+
go:0016104 triterpenoid biosynthetic process biological_process

LXL04_032798

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source ID-
LocationCM104805.1:29441910-29443493 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA08G205390

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source IDTkA08G205390
LocationCM104805.1:29447303-29455115 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkAUNG042360

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source IDTkAUNG042360;TkA05G423610;TkA07G019450;TkA08G206530
LocationCM104805.1:29717175-29719867 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0016117 carotenoid biosynthetic process biological_process

TkA02G537400

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source IDTkA02G537400;TkA04G085260;TkA08G208950
LocationCM104805.1:30377850-30378802 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

LXL04_032846

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source ID-
LocationCM104805.1:30421132-30421449 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

LXL04_032847

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source ID-
LocationCM104805.1:30426324-30430068 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA08G209260

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source IDTkA08G209260
LocationCM104805.1:30474280-30474914 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA08G208960

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source IDTkA08G208960;TkA08G209130
LocationCM104805.1:30565640-30566978 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

TkA08G208680

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source IDTkA08G208680;TkA08G208830;TkA08G209600
LocationCM104805.1:30589892-30590902 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

LXL04_033183

Terpenoid metabolismTerpenoid metabolismLow · score 2
Source ID-
LocationCM104805.1:37827726-37836466 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0016104 triterpenoid biosynthetic process biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.