Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

300 candidates match the current filter; 10 are shown per page (page 27 of 30). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_033945
TK1151: -
OH-1004: LXL04_033945
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:67660599-67661005
+
GO:0016114
LXL04_033947
TK1151: -
OH-1004: LXL04_033947
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:67678877-67679283
+
GO:0016114
LXL04_034585
TK1151: -
OH-1004: LXL04_034585
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-Prot CM104805.1:108323232-108323511
+
GO:0016114
TkA08G433330
TK1151: TkA08G433330
OH-1004: LXL04_034748
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:115718949-115720556
+
GO:0016114
TkA04G169480
TK1151: TkA04G169480
OH-1004: LXL04_035089
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:13926641-13928324
+
GO:0008299
TkA04G128060
TK1151: TkA04G128060
OH-1004: LXL04_035473
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:23243659-23245942
-
GO:0008299
LXL04_036312
TK1151: -
OH-1004: LXL04_036312
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:39709908-39712838
+
GO:0016740
TkA04G040030
TK1151: TkA04G040030;TkA04G052750;TkA04G052770
OH-1004: LXL04_036351
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:40566729-40571962
+
GO:0016740
LXL04_036370
TK1151: -
OH-1004: LXL04_036370
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:40943661-40944626
-
GO:0016740
TkA02G501290
TK1151: TkA02G501290;TkA04G029070
OH-1004: LXL04_036689
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104806.1:46712144-46713455
+
GO:0016740

LXL04_033945

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:67660599-67661005 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_033947

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:67678877-67679283 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_034585

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:108323232-108323511 +
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidenceGO:0016114

TkA08G433330

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA08G433330
LocationCM104805.1:115718949-115720556 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA04G169480

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G169480
LocationCM104806.1:13926641-13928324 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA04G128060

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G128060
LocationCM104806.1:23243659-23245942 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

LXL04_036312

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104806.1:39709908-39712838 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA04G040030

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA04G040030;TkA04G052750;TkA04G052770
LocationCM104806.1:40566729-40571962 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

LXL04_036370

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104806.1:40943661-40944626 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA02G501290

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G501290;TkA04G029070
LocationCM104806.1:46712144-46713455 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.