Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 11 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA03G497190
TK1151: TkA03G497190
OH-1004: LXL04_010093
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-Prot CM104800.1:139830927-139831489
+
go:0010311 lateral root formation biological_process
TkA03G565670
TK1151: TkA03G565670
OH-1004: LXL04_011107
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:157974040-157978768
-
go:0010053 root epidermal cell differentiation biological_process
TkA02G360640
TK1151: TkA02G360640;TkA03G581720;TkA07G110140
OH-1004: LXL04_011309
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:162340852-162343236
+
go:0006979 response to oxidative stress biological_process
TkA03G593960
TK1151: TkA03G593960;TkA05G342030
OH-1004: LXL04_011493
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:165602383-165605043
+
go:0048527 lateral root development biological_process
TkAUNG059540
TK1151: TkAUNG059540;TkA03G604980
OH-1004: LXL04_011604
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:168044832-168046443
+
go:0010078 maintenance of root meristem identity biological_process
LXL04_011731
TK1151: -
OH-1004: LXL04_011731
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:170398003-170399936
+
go:0006979 response to oxidative stress biological_process
TkA03G615240
TK1151: TkA03G615240;TkA06G222780
OH-1004: LXL04_011735
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:170442610-170444553
-
go:0010102 lateral root morphogenesis biological_process
TkA02G602620
TK1151: TkA02G602620;TkA03G355420;TkA03G355430;TkA04G146560
OH-1004: LXL04_011932
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:3012728-3015466
-
go:0006979 response to oxidative stress biological_process
TkA02G580940
TK1151: TkA02G580940
OH-1004: LXL04_012216
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:8497074-8498120
+
go:0006950 response to stress biological_process
TkA02G579420
TK1151: TkA02G579420
OH-1004: LXL04_012236
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:8918294-8920672
+
go:0010311 lateral root formation biological_process

TkA03G497190

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G497190
LocationCM104800.1:139830927-139831489 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidencego:0010311 lateral root formation biological_process

TkA03G565670

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G565670
LocationCM104800.1:157974040-157978768 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

TkA02G360640

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G360640;TkA03G581720;TkA07G110140
LocationCM104800.1:162340852-162343236 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA03G593960

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G593960;TkA05G342030
LocationCM104800.1:165602383-165605043 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048527 lateral root development biological_process

TkAUNG059540

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG059540;TkA03G604980
LocationCM104800.1:168044832-168046443 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

LXL04_011731

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104800.1:170398003-170399936 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA03G615240

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G615240;TkA06G222780
LocationCM104800.1:170442610-170444553 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010102 lateral root morphogenesis biological_process

TkA02G602620

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G602620;TkA03G355420;TkA03G355430;TkA04G146560
LocationCM104801.1:3012728-3015466 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA02G580940

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G580940
LocationCM104801.1:8497074-8498120 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

TkA02G579420

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G579420
LocationCM104801.1:8918294-8920672 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.