Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 10 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA07G346510
TK1151: TkA07G346510
OH-1004: LXL04_008498
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtCoexpression CM104800.1:101366663-101370355
-
go:0006979 response to oxidative stress biological_process
TkA03G393440
TK1151: TkA03G393440;TkA08G062700
OH-1004: LXL04_009021
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:116300233-116301134
-
go:0006970 response to osmotic stress biological_process
TkA03G393890
TK1151: TkA03G393890
OH-1004: LXL04_009028
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:116469201-116470991
-
go:0010102 lateral root morphogenesis biological_process
TkA03G393950
TK1151: TkA03G393950
OH-1004: LXL04_009030
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:116496703-116498592
-
go:0010102 lateral root morphogenesis biological_process
LXL04_009132
TK1151: -
OH-1004: LXL04_009132
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:118484655-118486628
-
go:0010015 root morphogenesis biological_process
TkA03G411860
TK1151: TkA03G411860
OH-1004: LXL04_009230
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:121024662-121025912
+
go:0006970 response to osmotic stress biological_process
TkA03G413120
TK1151: TkA03G413120
OH-1004: LXL04_009231
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:121045750-121047009
-
go:0006970 response to osmotic stress biological_process
TkAUNG059510
TK1151: TkAUNG059510;TkAUNG059530;TkAUNG059550;TkA03G443110;TkA04G100150
OH-1004: LXL04_009506
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:127649358-127655296
-
go:0010078 maintenance of root meristem identity biological_process
TkA03G443920
TK1151: TkA03G443920
OH-1004: LXL04_009515
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:127946697-127950155
+
go:0010078 maintenance of root meristem identity biological_process
TkA03G473880
TK1151: TkA03G473880
OH-1004: LXL04_009803
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:133905875-133908043
-
go:0006970 response to osmotic stress biological_process

TkA07G346510

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA07G346510
LocationCM104800.1:101366663-101370355 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA03G393440

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G393440;TkA08G062700
LocationCM104800.1:116300233-116301134 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G393890

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G393890
LocationCM104800.1:116469201-116470991 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010102 lateral root morphogenesis biological_process

TkA03G393950

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G393950
LocationCM104800.1:116496703-116498592 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010102 lateral root morphogenesis biological_process

LXL04_009132

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104800.1:118484655-118486628 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010015 root morphogenesis biological_process

TkA03G411860

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G411860
LocationCM104800.1:121024662-121025912 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G413120

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G413120
LocationCM104800.1:121045750-121047009 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkAUNG059510

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG059510;TkAUNG059530;TkAUNG059550;TkA03G443110;TkA04G100150
LocationCM104800.1:127649358-127655296 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA03G443920

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G443920
LocationCM104800.1:127946697-127950155 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA03G473880

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G473880
LocationCM104800.1:133905875-133908043 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.