Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 92 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA06G008030
TK1151: TkA06G008030
OH-1004: LXL04_026504
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:127464410-127467025
+
GO:0016114
TkA06G007840
TK1151: TkA06G007840
OH-1004: LXL04_026506
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:127496772-127499776
+
GO:0016114
TkA06G007840
TK1151: TkA06G007840
OH-1004: LXL04_026506
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:127496772-127499776
+
GO:0016114
TkA06G007510
TK1151: TkA06G007510
OH-1004: LXL04_026515
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:127578797-127583102
+
go:0048364 root development biological_process
TkA06G006320
TK1151: TkA06G006320
OH-1004: LXL04_026542
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:127985728-127987217
+
GO:0016740
TkA06G467280
TK1151: TkA06G467280;TkA07G004730
OH-1004: LXL04_026734
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104804.1:2156874-2159116
+
go:0006970 response to osmotic stress biological_process
TkA07G006570
TK1151: TkA07G006570
OH-1004: LXL04_026768
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:2675209-2678066
-
go:0010082 regulation of root meristem growth biological_process
TkA07G009450
TK1151: TkA07G009450;TkA07G047150
OH-1004: LXL04_026810
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:3294743-3299854
+
GO:0016114
TkA07G009450
TK1151: TkA07G009450;TkA07G047150
OH-1004: LXL04_026810
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:3294743-3299854
+
GO:0016114
TkA07G009610
TK1151: TkA07G009610
OH-1004: LXL04_026811
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104804.1:3321916-3327525
+
GO:0016114

TkA06G008030

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G008030
LocationCM104803.1:127464410-127467025 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G007840

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA06G007840
LocationCM104803.1:127496772-127499776 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G007840

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G007840
LocationCM104803.1:127496772-127499776 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G007510

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G007510
LocationCM104803.1:127578797-127583102 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

TkA06G006320

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G006320
LocationCM104803.1:127985728-127987217 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

TkA06G467280

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G467280;TkA07G004730
LocationCM104804.1:2156874-2159116 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA07G006570

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA07G006570
LocationCM104804.1:2675209-2678066 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010082 regulation of root meristem growth biological_process

TkA07G009450

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA07G009450;TkA07G047150
LocationCM104804.1:3294743-3299854 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA07G009450

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA07G009450;TkA07G047150
LocationCM104804.1:3294743-3299854 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA07G009610

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA07G009610
LocationCM104804.1:3321916-3327525 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.