Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 88 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA06G143500
TK1151: TkA06G143500;TkA06G143510
OH-1004: LXL04_024442
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:90763078-90765754
-
go:0006970 response to osmotic stress biological_process
TkA03G091810
TK1151: TkA03G091810;TkA06G142250
OH-1004: LXL04_024451
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:91036003-91037271
-
go:0010102 lateral root morphogenesis biological_process
TkA06G134330
TK1151: TkA06G134330
OH-1004: LXL04_024531
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:93159005-93160081
-
GO:0008299
TkA03G353780
TK1151: TkA03G353780;TkA03G501090;TkA03G617430;TkA06G113340;TkA08G064670
OH-1004: LXL04_024736
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:97826167-97831870
+
GO:0008299
TkA06G097970
TK1151: TkA06G097970
OH-1004: LXL04_024888
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:101545925-101547031
+
GO:0008299
TkA06G097930
TK1151: TkA06G097930
OH-1004: LXL04_024889
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:101553174-101554972
-
GO:0016114
TkA06G097850
TK1151: TkA06G097850
OH-1004: LXL04_024890
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:101566202-101568006
+
GO:0016114
TkA06G097050
TK1151: TkA06G097050
OH-1004: LXL04_024898
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104803.1:101719979-101723150
-
go:0010311 lateral root formation biological_process
TkA06G096500
TK1151: TkA06G096500
OH-1004: LXL04_024906
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:101955043-101956723
-
GO:0016114
TkA06G096400
TK1151: TkA06G096400
OH-1004: LXL04_024907
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104803.1:101969009-101970691
+
GO:0016114

TkA06G143500

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G143500;TkA06G143510
LocationCM104803.1:90763078-90765754 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G091810

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G091810;TkA06G142250
LocationCM104803.1:91036003-91037271 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010102 lateral root morphogenesis biological_process

TkA06G134330

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G134330
LocationCM104803.1:93159005-93160081 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA03G353780

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G353780;TkA03G501090;TkA03G617430;TkA06G113340;TkA08G064670
LocationCM104803.1:97826167-97831870 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA06G097970

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G097970
LocationCM104803.1:101545925-101547031 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA06G097930

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G097930
LocationCM104803.1:101553174-101554972 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G097850

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G097850
LocationCM104803.1:101566202-101568006 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G097050

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G097050
LocationCM104803.1:101719979-101723150 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

TkA06G096500

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G096500
LocationCM104803.1:101955043-101956723 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA06G096400

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA06G096400
LocationCM104803.1:101969009-101970691 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.