Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 85 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA05G399220
TK1151: TkA05G399220
OH-1004: LXL04_021484
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:131080015-131082622
+
go:0010082 regulation of root meristem growth biological_process
TkA05G399390
TK1151: TkA05G399390;TkA05G400010
OH-1004: LXL04_021493
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:131142497-131144074
-
GO:0008299
LXL04_021516
TK1151: -
OH-1004: LXL04_021516
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:131502285-131504471
+
GO:0016114
TkA03G416190
TK1151: TkA03G416190;TkA05G409060
OH-1004: LXL04_021595
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:133048868-133050893
-
go:0006950 response to stress biological_process
TkA05G416450
TK1151: TkA05G416450
OH-1004: LXL04_021699
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:135517899-135519532
-
go:0006970 response to osmotic stress biological_process
TkAUNG024690
TK1151: TkAUNG024690;TkA08G354230
OH-1004: LXL04_021889
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:139651413-139655754
-
GO:0016114
TkA02G409560
TK1151: TkA02G409560
OH-1004: LXL04_021900
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104802.1:139872881-139876264
-
go:0010449 root meristem growth biological_process
TkAUNG085910
TK1151: TkAUNG085910
OH-1004: LXL04_021903
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:139934120-139939621
+
go:0006979 response to oxidative stress biological_process
TkA05G432650
TK1151: TkA05G432650
OH-1004: LXL04_021941
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:140770196-140771287
-
go:0009611 response to wounding biological_process
TkA05G443990
TK1151: TkA05G443990
OH-1004: LXL04_022076
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:144335591-144341358
+
go:0048364 root development biological_process

TkA05G399220

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA05G399220
LocationCM104802.1:131080015-131082622 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010082 regulation of root meristem growth biological_process

TkA05G399390

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA05G399390;TkA05G400010
LocationCM104802.1:131142497-131144074 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

LXL04_021516

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104802.1:131502285-131504471 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA03G416190

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G416190;TkA05G409060
LocationCM104802.1:133048868-133050893 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006950 response to stress biological_process

TkA05G416450

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA05G416450
LocationCM104802.1:135517899-135519532 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkAUNG024690

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG024690;TkA08G354230
LocationCM104802.1:139651413-139655754 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G409560

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA02G409560
LocationCM104802.1:139872881-139876264 -
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0010449 root meristem growth biological_process

TkAUNG085910

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkAUNG085910
LocationCM104802.1:139934120-139939621 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA05G432650

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA05G432650
LocationCM104802.1:140770196-140771287 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA05G443990

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA05G443990
LocationCM104802.1:144335591-144341358 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.