Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 66 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G398970
TK1151: TkA01G398970;TkA03G500830
OH-1004: LXL04_010125
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:140650908-140652436
-
go:0006970 response to osmotic stress biological_process
TkA03G501650
TK1151: TkA03G501650;TkA04G076050
OH-1004: LXL04_010138
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:140853852-140856732
-
go:0010311 lateral root formation biological_process
TkA03G502610
TK1151: TkA03G502610;TkA07G039490
OH-1004: LXL04_010144
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104800.1:141024388-141025613
-
go:0006970 response to osmotic stress biological_process
TkA03G513450
TK1151: TkA03G513450
OH-1004: LXL04_010237
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:142678281-142681192
-
GO:0008299
TkA03G513520
TK1151: TkA03G513520
OH-1004: LXL04_010240
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:142694018-142697297
-
GO:0016740
LXL04_010276
TK1151: -
OH-1004: LXL04_010276
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:143591597-143591900
-
go:0006970 response to osmotic stress biological_process
TkA03G518320
TK1151: TkA03G518320;TkA03G518380
OH-1004: LXL04_010308
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:143958896-143961172
-
GO:0016114
TkA03G518320
TK1151: TkA03G518320;TkA03G518380
OH-1004: LXL04_010308
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:143958896-143961172
-
GO:0016114
TkAUNG096030
TK1151: TkAUNG096030;TkA08G216360
OH-1004: LXL04_010407
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:146186479-146187087
+
GO:0016114
TkAUNG096030
TK1151: TkAUNG096030;TkA08G216360
OH-1004: LXL04_010407
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:146186479-146187087
+
GO:0016114

TkA01G398970

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA01G398970;TkA03G500830
LocationCM104800.1:140650908-140652436 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G501650

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G501650;TkA04G076050
LocationCM104800.1:140853852-140856732 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

TkA03G502610

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G502610;TkA07G039490
LocationCM104800.1:141024388-141025613 -
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G513450

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G513450
LocationCM104800.1:142678281-142681192 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA03G513520

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G513520
LocationCM104800.1:142694018-142697297 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_010276

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104800.1:143591597-143591900 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G518320

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA03G518320;TkA03G518380
LocationCM104800.1:143958896-143961172 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G518320

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G518320;TkA03G518380
LocationCM104800.1:143958896-143961172 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkAUNG096030

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkAUNG096030;TkA08G216360
LocationCM104800.1:146186479-146187087 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkAUNG096030

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG096030;TkA08G216360
LocationCM104800.1:146186479-146187087 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.