Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 65 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_009632
TK1151: -
OH-1004: LXL04_009632
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:130007491-130008252
-
go:0009611 response to wounding biological_process
TkA03G461620
TK1151: TkA03G461620
OH-1004: LXL04_009676
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:131074245-131076734
-
GO:0016740
TkA03G462260
TK1151: TkA03G462260
OH-1004: LXL04_009683
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:131179279-131183781
+
GO:0008299
LXL04_009770
TK1151: -
OH-1004: LXL04_009770
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:132996870-132997846
-
go:0006970 response to osmotic stress biological_process
TkA03G471060
TK1151: TkA03G471060
OH-1004: LXL04_009775
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:133158566-133162047
+
go:0010333 terpene synthase activity molecular_function
TkA03G471930
TK1151: TkA03G471930;TkA03G471940
OH-1004: LXL04_009791
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:133446561-133448220
+
GO:0016114
TkA03G471970
TK1151: TkA03G471970
OH-1004: LXL04_009792
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:133466301-133468285
+
GO:0008299
TkA03G494300
TK1151: TkA03G494300;TkA03G495250
OH-1004: LXL04_010072
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:139365691-139367676
+
GO:0016114
LXL04_010112
TK1151: -
OH-1004: LXL04_010112
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104800.1:140379868-140381136
+
GO:0016740
TkA03G499170
TK1151: TkA03G499170
OH-1004: LXL04_010113
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:140390552-140392336
+
GO:0016740

LXL04_009632

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104800.1:130007491-130008252 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA03G461620

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G461620
LocationCM104800.1:131074245-131076734 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G462260

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G462260
LocationCM104800.1:131179279-131183781 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

LXL04_009770

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104800.1:132996870-132997846 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G471060

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA03G471060
LocationCM104800.1:133158566-133162047 +
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010333 terpene synthase activity molecular_function

TkA03G471930

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G471930;TkA03G471940
LocationCM104800.1:133446561-133448220 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016114

TkA03G471970

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G471970
LocationCM104800.1:133466301-133468285 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA03G494300

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G494300;TkA03G495250
LocationCM104800.1:139365691-139367676 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_010112

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:140379868-140381136 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G499170

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G499170
LocationCM104800.1:140390552-140392336 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.