Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 63 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA03G325630
TK1151: TkA03G325630
OH-1004: LXL04_007509
Terpenoid metabolism
Terpenoid metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:51008832-51011179
+
GO:0006720
TkA03G192730
TK1151: TkA03G192730
OH-1004: LXL04_007581
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:52991156-52994022
-
go:0006970 response to osmotic stress biological_process
TkA03G193790
TK1151: TkA03G193790
OH-1004: LXL04_007585
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:53197768-53205881
-
GO:0016740
TkA05G289620
TK1151: TkA05G289620
OH-1004: LXL04_007882
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:70233972-70237230
+
GO:0016740
TkA03G389990
TK1151: TkA03G389990
OH-1004: LXL04_008256
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:94984722-94987063
-
GO:0016114
TkA03G358710
TK1151: TkA03G358710;TkA03G554310
OH-1004: LXL04_008561
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:102800228-102800974
-
go:0006970 response to osmotic stress biological_process
TkA03G332610
TK1151: TkA03G332610;TkA03G561820;TkA06G048710
OH-1004: LXL04_008789
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:108880457-108881863
+
go:0009651 response to salt stress biological_process
LXL04_008968
TK1151: -
OH-1004: LXL04_008968
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104800.1:114418300-114419061
+
go:0009611 response to wounding biological_process
TkA03G300890
TK1151: TkA03G300890
OH-1004: LXL04_008981
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:114849265-114851137
+
GO:0016740
TkA03G300720
TK1151: TkA03G300720
OH-1004: LXL04_008982
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:114894878-114896787
+
GO:0016740

TkA03G325630

Terpenoid metabolismTerpenoid metabolismMedium · score 6
Source IDTkA03G325630
LocationCM104800.1:51008832-51011179 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0006720

TkA03G192730

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G192730
LocationCM104800.1:52991156-52994022 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G193790

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G193790
LocationCM104800.1:53197768-53205881 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA05G289620

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA05G289620
LocationCM104800.1:70233972-70237230 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G389990

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G389990
LocationCM104800.1:94984722-94987063 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G358710

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G358710;TkA03G554310
LocationCM104800.1:102800228-102800974 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G332610

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G332610;TkA03G561820;TkA06G048710
LocationCM104800.1:108880457-108881863 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

LXL04_008968

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104800.1:114418300-114419061 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA03G300890

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G300890
LocationCM104800.1:114849265-114851137 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA03G300720

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G300720
LocationCM104800.1:114894878-114896787 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.