Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 62 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA03G080370
TK1151: TkA03G080370
OH-1004: LXL04_006848
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:27562223-27562828
+
go:0009651 response to salt stress biological_process
TkA03G084160
TK1151: TkA03G084160
OH-1004: LXL04_006868
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:28424311-28427005
+
GO:0016740
TkA02G565680
TK1151: TkA02G565680
OH-1004: LXL04_007011
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:33697739-33699470
+
GO:0016114
TkA03G103720
TK1151: TkA03G103720
OH-1004: LXL04_007018
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:33846152-33847563
+
GO:0008299
TkA02G477400
TK1151: TkA02G477400;TkA03G108120
OH-1004: LXL04_007062
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:34968648-34978505
+
GO:0016740
LXL04_007136
TK1151: -
OH-1004: LXL04_007136
Terpenoid metabolism
Terpenoid metabolism
Medium
score 6
FunctionGOExpressionLocalizationSwiss-ProtCoexpression CM104800.1:37094195-37095871
-
go:0010436 carotenoid dioxygenase activity molecular_function
TkA03G137290
TK1151: TkA03G137290
OH-1004: LXL04_007205
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:39506769-39513818
+
GO:0008299
LXL04_007243
TK1151: -
OH-1004: LXL04_007243
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:40904088-40904702
+
GO:0016114
TkA03G164130
TK1151: TkA03G164130;TkA03G169300
OH-1004: LXL04_007395
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:46575313-46577343
-
GO:0016114
TkA03G325630
TK1151: TkA03G325630
OH-1004: LXL04_007509
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:51008832-51011179
+
GO:0008299

TkA03G080370

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G080370
LocationCM104800.1:27562223-27562828 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA03G084160

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G084160
LocationCM104800.1:28424311-28427005 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA02G565680

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G565680
LocationCM104800.1:33697739-33699470 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G103720

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G103720
LocationCM104800.1:33846152-33847563 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA02G477400

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G477400;TkA03G108120
LocationCM104800.1:34968648-34978505 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

LXL04_007136

Terpenoid metabolismTerpenoid metabolismMedium · score 6
Source ID-
LocationCM104800.1:37094195-37095871 -
EvidenceFunctionGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0010436 carotenoid dioxygenase activity molecular_function

TkA03G137290

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G137290
LocationCM104800.1:39506769-39513818 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

LXL04_007243

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104800.1:40904088-40904702 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G164130

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G164130;TkA03G169300
LocationCM104800.1:46575313-46577343 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G325630

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA03G325630
LocationCM104800.1:51008832-51011179 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.