Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 61 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_006003
TK1151: -
OH-1004: LXL04_006003
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104799.1:176856205-176857439
-
GO:0016740
TkA01G001840
TK1151: TkA01G001840
OH-1004: LXL04_006010
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:176944355-176950704
-
GO:0008299
LXL04_006011
TK1151: -
OH-1004: LXL04_006011
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104799.1:176950720-176955451
-
GO:0008299
TkA03G016220
TK1151: TkA03G016220
OH-1004: LXL04_006186
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:3409166-3409802
+
go:0009651 response to salt stress biological_process
TkA05G326100
TK1151: TkA05G326100
OH-1004: LXL04_006214
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104800.1:4032599-4033528
+
go:0006970 response to osmotic stress biological_process
TkA06G156760
TK1151: TkA06G156760
OH-1004: LXL04_006360
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:8727682-8728398
-
go:0009611 response to wounding biological_process
TkAUNG032340
TK1151: TkAUNG032340;TkA04G051650
OH-1004: LXL04_006392
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:9564173-9565832
-
go:0006970 response to osmotic stress biological_process
TkA03G039760
TK1151: TkA03G039760
OH-1004: LXL04_006468
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:11451020-11470766
-
go:0006979 response to oxidative stress biological_process
TkA03G042450
TK1151: TkA03G042450;TkA08G074070
OH-1004: LXL04_006498
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:12201916-12202443
+
go:0010053 root epidermal cell differentiation biological_process
LXL04_006637
TK1151: -
OH-1004: LXL04_006637
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:20480762-20483212
-
go:0010311 lateral root formation biological_process

LXL04_006003

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104799.1:176856205-176857439 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0016740

TkA01G001840

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G001840
LocationCM104799.1:176944355-176950704 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

LXL04_006011

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104799.1:176950720-176955451 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA03G016220

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G016220
LocationCM104800.1:3409166-3409802 +
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA05G326100

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA05G326100
LocationCM104800.1:4032599-4033528 +
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA06G156760

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA06G156760
LocationCM104800.1:8727682-8728398 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkAUNG032340

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkAUNG032340;TkA04G051650
LocationCM104800.1:9564173-9565832 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA03G039760

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G039760
LocationCM104800.1:11451020-11470766 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA03G042450

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA03G042450;TkA08G074070
LocationCM104800.1:12201916-12202443 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

LXL04_006637

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104800.1:20480762-20483212 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.