Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 54 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G524300
TK1151: TkA01G524300;TkA03G142750;TkA04G415110
OH-1004: LXL04_001581
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:29386886-29388025
-
go:0009611 response to wounding biological_process
TkA01G522970
TK1151: TkA01G522970
OH-1004: LXL04_001598
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:29822753-29827340
-
GO:0008299
TkA01G521500
TK1151: TkA01G521500
OH-1004: LXL04_001626
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:30334051-30334836
+
go:0009651 response to salt stress biological_process
TkA01G216890
TK1151: TkA01G216890;TkA01G509320
OH-1004: LXL04_001800
Terpenoid metabolism
Terpenoid metabolism
Medium
score 6
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:33654659-33656407
-
go:0010436 carotenoid dioxygenase activity molecular_function
TkA01G505340
TK1151: TkA01G505340
OH-1004: LXL04_001833
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:34706746-34708594
-
go:0006970 response to osmotic stress biological_process
TkA01G499770
TK1151: TkA01G499770
OH-1004: LXL04_001903
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:36531195-36533379
-
GO:0008299
TkA01G498380
TK1151: TkA01G498380;TkA03G167100
OH-1004: LXL04_001919
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:36890705-36893344
-
go:0006950 response to stress biological_process
TkA02G415600
TK1151: TkA02G415600;TkA02G484220;TkA03G568640;TkA04G412070
OH-1004: LXL04_001994
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104799.1:38609811-38612529
+
GO:0016114
TkA01G490150
TK1151: TkA01G490150
OH-1004: LXL04_002018
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:39702966-39703723
+
go:0006970 response to osmotic stress biological_process
TkA01G001540
TK1151: TkA01G001540;TkA01G485210;TkA03G363400;TkA04G345630;TkA07G365100
OH-1004: LXL04_002061
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104799.1:41230311-41231096
+
GO:0016740

TkA01G524300

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA01G524300;TkA03G142750;TkA04G415110
LocationCM104799.1:29386886-29388025 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA01G522970

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G522970
LocationCM104799.1:29822753-29827340 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA01G521500

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA01G521500
LocationCM104799.1:30334051-30334836 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA01G216890

Terpenoid metabolismTerpenoid metabolismMedium · score 6
Source IDTkA01G216890;TkA01G509320
LocationCM104799.1:33654659-33656407 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010436 carotenoid dioxygenase activity molecular_function

TkA01G505340

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA01G505340
LocationCM104799.1:34706746-34708594 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G499770

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G499770
LocationCM104799.1:36531195-36533379 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA01G498380

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA01G498380;TkA03G167100
LocationCM104799.1:36890705-36893344 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006950 response to stress biological_process

TkA02G415600

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA02G415600;TkA02G484220;TkA03G568640;TkA04G412070
LocationCM104799.1:38609811-38612529 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA01G490150

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA01G490150
LocationCM104799.1:39702966-39703723 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G001540

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA01G001540;TkA01G485210;TkA03G363400;TkA04G345630;TkA07G365100
LocationCM104799.1:41230311-41231096 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.