Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

8 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT1JQ991925.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT2JQ991926.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT3JQ991927.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assaysTbSRPP1JQ991928.1SRPPREF/SRPP rubber-particle proteinsSmall rubber-particle proteinA_direct_experiment
TbSRPP1 is a direct experimental reference associated with rubber-particle formation.
External particle-protein evidence, not direct validation in T. kok-saghyz.
10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbRTAKP763637.1RTALatex/root associatedRubber transferase activator referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS1KJ911908.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS2KJ911910.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbREFMF471639.1REFREF/SRPP rubber-particle proteinsRubber-particle protein referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records

Laticiferous dandelion · TbCPT1

Sequence IDJQ991925.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT2

Sequence IDJQ991926.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT3

Sequence IDJQ991927.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbSRPP1

Sequence IDJQ991928.1
StepREF/SRPP rubber-particle proteins · SRPP
EvidenceTbSRPP1 is a direct experimental reference associated with rubber-particle formation.
BoundaryExternal particle-protein evidence, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbRTA

Sequence IDKP763637.1
StepLatex/root associated · RTA
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS1

Sequence IDKJ911908.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS2

Sequence IDKJ911910.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbREF

Sequence IDMF471639.1
StepREF/SRPP rubber-particle proteins · REF
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 49 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_033675
TK1151: -
OH-1004: LXL04_033675
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:52686546-52687328
+
GO:0016114
TkA08G297840
TK1151: TkA08G297840;TkA08G298110;TkA08G298800
OH-1004: LXL04_033676
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:52736712-52740252
+
GO:0016114
LXL04_034589
TK1151: -
OH-1004: LXL04_034589
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:108440406-108443357
-
go:0009651 response to salt stress biological_process
TkA08G433330
TK1151: TkA08G433330
OH-1004: LXL04_034748
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:115718949-115720556
+
GO:0016114
TkA08G435740
TK1151: TkA08G435740
OH-1004: LXL04_034777
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:116425399-116428121
-
go:0010053 root epidermal cell differentiation biological_process
LXL04_034809
TK1151: -
OH-1004: LXL04_034809
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtCoexpression CM104806.1:2025250-2026669
+
go:0048527 lateral root development biological_process
TkA04G168640
TK1151: TkA04G168640
OH-1004: LXL04_035097
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPI CM104806.1:14179785-14180834
+
go:0006950 response to stress biological_process
TkAUNG005030
TK1151: TkAUNG005030;TkAUNG005910;TkAUNG008300;TkA01G382650;TkA04G107000
OH-1004: LXL04_035807
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:29282808-29287984
-
go:0006970 response to osmotic stress biological_process
TkA02G404720
TK1151: TkA02G404720;TkA04G074260
OH-1004: LXL04_036114
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104806.1:35933044-35936835
+
go:0009611 response to wounding biological_process
TkA02G460460
TK1151: TkA02G460460;TkA04G049900;TkA04G504850;TkA05G349470
OH-1004: LXL04_036403
MVA/MEP and isoprenoid
Mevalonate pathway
High
score 8
FunctionGOExpressionLocalizationSwiss-ProtCoexpression CM104806.1:41355832-41359443
-
go:0004631 phosphomevalonate kinase activity molecular_function

LXL04_033675

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source ID-
LocationCM104805.1:52686546-52687328 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA08G297840

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA08G297840;TkA08G298110;TkA08G298800
LocationCM104805.1:52736712-52740252 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_034589

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104805.1:108440406-108443357 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA08G433330

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA08G433330
LocationCM104805.1:115718949-115720556 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA08G435740

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA08G435740
LocationCM104805.1:116425399-116428121 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

LXL04_034809

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104806.1:2025250-2026669 +
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0048527 lateral root development biological_process

TkA04G168640

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA04G168640
LocationCM104806.1:14179785-14180834 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0006950 response to stress biological_process

TkAUNG005030

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG005030;TkAUNG005910;TkAUNG008300;TkA01G382650;TkA04G107000
LocationCM104806.1:29282808-29287984 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA02G404720

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G404720;TkA04G074260
LocationCM104806.1:35933044-35936835 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G460460

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 8
Source IDTkA02G460460;TkA04G049900;TkA04G504850;TkA05G349470
LocationCM104806.1:41355832-41359443 -
EvidenceFunctionGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0004631 phosphomevalonate kinase activity molecular_function

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.