Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

8 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT1JQ991925.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT2JQ991926.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT3JQ991927.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assaysTbSRPP1JQ991928.1SRPPREF/SRPP rubber-particle proteinsSmall rubber-particle proteinA_direct_experiment
TbSRPP1 is a direct experimental reference associated with rubber-particle formation.
External particle-protein evidence, not direct validation in T. kok-saghyz.
10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbRTAKP763637.1RTALatex/root associatedRubber transferase activator referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS1KJ911908.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS2KJ911910.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbREFMF471639.1REFREF/SRPP rubber-particle proteinsRubber-particle protein referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records

Laticiferous dandelion · TbCPT1

Sequence IDJQ991925.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT2

Sequence IDJQ991926.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT3

Sequence IDJQ991927.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbSRPP1

Sequence IDJQ991928.1
StepREF/SRPP rubber-particle proteins · SRPP
EvidenceTbSRPP1 is a direct experimental reference associated with rubber-particle formation.
BoundaryExternal particle-protein evidence, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbRTA

Sequence IDKP763637.1
StepLatex/root associated · RTA
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS1

Sequence IDKJ911908.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS2

Sequence IDKJ911910.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbREF

Sequence IDMF471639.1
StepREF/SRPP rubber-particle proteins · REF
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 34 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA08G255710
TK1151: TkA08G255710
OH-1004: LXL04_017480
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:150322025-150323966
-
GO:0016114
LXL04_017485
TK1151: -
OH-1004: LXL04_017485
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:151404262-151407736
-
GO:0016114
TkA02G035170
TK1151: TkA02G035170;TkA02G037580
OH-1004: LXL04_017504
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:152103625-152107494
+
go:0010053 root epidermal cell differentiation biological_process
TkA02G033560
TK1151: TkA02G033560;TkA02G033670
OH-1004: LXL04_017542
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-Prot CM104801.1:152867160-152869339
+
GO:0016114
TkA02G033190
TK1151: TkA02G033190;TkA02G033740
OH-1004: LXL04_017543
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:152879504-152883854
+
GO:0016114
TkA02G561870
TK1151: TkA02G561870;TkA08G052360
OH-1004: LXL04_017765
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:902031-904614
-
go:0010053 root epidermal cell differentiation biological_process
TkA08G049640
TK1151: TkA08G049640
OH-1004: LXL04_017803
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:1422552-1424818
+
go:0006970 response to osmotic stress biological_process
TkA08G041650
TK1151: TkA08G041650
OH-1004: LXL04_017903
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:3271320-3274212
-
go:0006979 response to oxidative stress biological_process
TkA08G041370
TK1151: TkA08G041370;TkA08G041380;TkA08G041390;TkA08G041400
OH-1004: LXL04_017906
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:3330089-3337327
-
go:0010494 cytoplasmic stress granule cellular_component
TkA08G040470
TK1151: TkA08G040470
OH-1004: LXL04_017917
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:3548636-3550104
-
go:0006970 response to osmotic stress biological_process

TkA08G255710

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA08G255710
LocationCM104801.1:150322025-150323966 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_017485

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source ID-
LocationCM104801.1:151404262-151407736 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G035170

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G035170;TkA02G037580
LocationCM104801.1:152103625-152107494 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

TkA02G033560

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA02G033560;TkA02G033670
LocationCM104801.1:152867160-152869339 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016114

TkA02G033190

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA02G033190;TkA02G033740
LocationCM104801.1:152879504-152883854 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G561870

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G561870;TkA08G052360
LocationCM104802.1:902031-904614 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

TkA08G049640

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA08G049640
LocationCM104802.1:1422552-1424818 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA08G041650

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA08G041650
LocationCM104802.1:3271320-3274212 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA08G041370

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA08G041370;TkA08G041380;TkA08G041390;TkA08G041400
LocationCM104802.1:3330089-3337327 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010494 cytoplasmic stress granule cellular_component

TkA08G040470

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA08G040470
LocationCM104802.1:3548636-3550104 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.