Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 32 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_015620
TK1151: -
OH-1004: LXL04_015620
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:77809116-77812009
+
GO:0016114
TkA02G269360
TK1151: TkA02G269360
OH-1004: LXL04_015951
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:100159606-100163105
-
go:0009611 response to wounding biological_process
TkA02G270790
TK1151: TkA02G270790
OH-1004: LXL04_015957
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:100424702-100430329
+
go:0009611 response to wounding biological_process
TkA02G271480
TK1151: TkA02G271480
OH-1004: LXL04_015962
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:100764202-100769414
+
go:0009611 response to wounding biological_process
TkA02G271500
TK1151: TkA02G271500
OH-1004: LXL04_015964
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:100769997-100774590
+
go:0009611 response to wounding biological_process
TkA02G272080
TK1151: TkA02G272080
OH-1004: LXL04_015965
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:100894756-100899109
+
go:0009611 response to wounding biological_process
LXL04_016031
TK1151: -
OH-1004: LXL04_016031
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:104555869-104563153
-
go:0009611 response to wounding biological_process
TkAUNG063980
TK1151: TkAUNG063980;TkA02G184870;TkA03G419600
OH-1004: LXL04_016140
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:112104016-112108087
+
go:0010053 root epidermal cell differentiation biological_process
TkA02G180040
TK1151: TkA02G180040
OH-1004: LXL04_016178
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:113362366-113364045
-
GO:0016114
LXL04_016180
TK1151: -
OH-1004: LXL04_016180
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:113396600-113398279
-
GO:0016114

LXL04_015620

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source ID-
LocationCM104801.1:77809116-77812009 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA02G269360

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G269360
LocationCM104801.1:100159606-100163105 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G270790

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G270790
LocationCM104801.1:100424702-100430329 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G271480

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G271480
LocationCM104801.1:100764202-100769414 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G271500

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G271500
LocationCM104801.1:100769997-100774590 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G272080

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G272080
LocationCM104801.1:100894756-100899109 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

LXL04_016031

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104801.1:104555869-104563153 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkAUNG063980

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG063980;TkA02G184870;TkA03G419600
LocationCM104801.1:112104016-112108087 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

TkA02G180040

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA02G180040
LocationCM104801.1:113362366-113364045 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_016180

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source ID-
LocationCM104801.1:113396600-113398279 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.