Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

8 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT1JQ991925.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT2JQ991926.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT3JQ991927.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assaysTbSRPP1JQ991928.1SRPPREF/SRPP rubber-particle proteinsSmall rubber-particle proteinA_direct_experiment
TbSRPP1 is a direct experimental reference associated with rubber-particle formation.
External particle-protein evidence, not direct validation in T. kok-saghyz.
10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbRTAKP763637.1RTALatex/root associatedRubber transferase activator referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS1KJ911908.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS2KJ911910.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbREFMF471639.1REFREF/SRPP rubber-particle proteinsRubber-particle protein referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records

Laticiferous dandelion · TbCPT1

Sequence IDJQ991925.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT2

Sequence IDJQ991926.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT3

Sequence IDJQ991927.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbSRPP1

Sequence IDJQ991928.1
StepREF/SRPP rubber-particle proteins · SRPP
EvidenceTbSRPP1 is a direct experimental reference associated with rubber-particle formation.
BoundaryExternal particle-protein evidence, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbRTA

Sequence IDKP763637.1
StepLatex/root associated · RTA
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS1

Sequence IDKJ911908.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS2

Sequence IDKJ911910.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbREF

Sequence IDMF471639.1
StepREF/SRPP rubber-particle proteins · REF
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 31 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA02G487080
TK1151: TkA02G487080
OH-1004: LXL04_013579
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104801.1:32066132-32068071
+
go:0010311 lateral root formation biological_process
TkA02G466600
TK1151: TkA02G466600
OH-1004: LXL04_013883
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:37390928-37394035
+
go:0009611 response to wounding biological_process
TkA02G465740
TK1151: TkA02G465740
OH-1004: LXL04_013897
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:37655768-37658163
+
go:0004663 rab geranylgeranyltransferase activity molecular_function
TkA02G271310
TK1151: TkA02G271310;TkA02G273690;TkA02G447740;TkA05G055900
OH-1004: LXL04_014203
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:43617682-43619090
+
go:0009611 response to wounding biological_process
TkA02G447450
TK1151: TkA02G447450
OH-1004: LXL04_014210
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:43688792-43692934
-
go:0010053 root epidermal cell differentiation biological_process
LXL04_014538
TK1151: -
OH-1004: LXL04_014538
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationSwiss-Prot CM104801.1:51953503-51954015
-
GO:0016114
TkAUNG067090
TK1151: TkAUNG067090;TkA02G412780
OH-1004: LXL04_014563
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:52555152-52555952
-
go:0006970 response to osmotic stress biological_process
TkA02G380070
TK1151: TkA02G380070
OH-1004: LXL04_014975
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:60671970-60675023
+
go:0004452 isopentenyl-diphosphate delta-isomerase activity molecular_function
TkAUNG003600
TK1151: TkAUNG003600;TkA02G312130
OH-1004: LXL04_015585
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104801.1:76845639-76852238
+
go:0006979 response to oxidative stress biological_process
TkAUNG003650
TK1151: TkAUNG003650;TkA04G394970
OH-1004: LXL04_015587
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104801.1:76879897-76884579
+
go:0006979 response to oxidative stress biological_process

TkA02G487080

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G487080
LocationCM104801.1:32066132-32068071 +
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

TkA02G466600

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G466600
LocationCM104801.1:37390928-37394035 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G465740

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA02G465740
LocationCM104801.1:37655768-37658163 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0004663 rab geranylgeranyltransferase activity molecular_function

TkA02G271310

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G271310;TkA02G273690;TkA02G447740;TkA05G055900
LocationCM104801.1:43617682-43619090 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA02G447450

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA02G447450
LocationCM104801.1:43688792-43692934 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

LXL04_014538

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source ID-
LocationCM104801.1:51953503-51954015 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidenceGO:0016114

TkAUNG067090

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG067090;TkA02G412780
LocationCM104801.1:52555152-52555952 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA02G380070

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA02G380070
LocationCM104801.1:60671970-60675023 +
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0004452 isopentenyl-diphosphate delta-isomerase activity molecular_function

TkAUNG003600

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG003600;TkA02G312130
LocationCM104801.1:76845639-76852238 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkAUNG003650

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkAUNG003650;TkA04G394970
LocationCM104801.1:76879897-76884579 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006979 response to oxidative stress biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.