Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 25 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G073790
TK1151: TkA01G073790
OH-1004: LXL04_005237
Terpenoid metabolism
Terpenoid metabolism
High
score 8
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:158178648-158181492
+
go:0010436 carotenoid dioxygenase activity molecular_function
LXL04_005252
TK1151: -
OH-1004: LXL04_005252
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationSwiss-ProtPPICoexpression CM104799.1:158912413-158912804
+
go:0010311 lateral root formation biological_process
TkA01G071950
TK1151: TkA01G071950
OH-1004: LXL04_005256
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:159048185-159053624
-
go:0006979 response to oxidative stress biological_process
TkA01G053380
TK1151: TkA01G053380;TkA01G053400;TkA03G231260
OH-1004: LXL04_005416
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:163134407-163141202
+
go:0010078 maintenance of root meristem identity biological_process
TkA01G018390
TK1151: TkA01G018390
OH-1004: LXL04_005758
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:172900148-172900978
+
go:0006970 response to osmotic stress biological_process
TkA01G006560
TK1151: TkA01G006560
OH-1004: LXL04_005929
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:175871285-175874519
+
go:0010078 maintenance of root meristem identity biological_process
TkA03G084520
TK1151: TkA03G084520
OH-1004: LXL04_006870
Latex/root related candidates
Latex/root associated candidates
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:28454435-28454839
+
go:0006970 response to osmotic stress biological_process
TkA02G565680
TK1151: TkA02G565680
OH-1004: LXL04_007011
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:33697739-33699470
+
GO:0016114
TkA03G137290
TK1151: TkA03G137290
OH-1004: LXL04_007205
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104800.1:39506769-39513818
+
GO:0008299
TkA03G164130
TK1151: TkA03G164130;TkA03G169300
OH-1004: LXL04_007395
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 8
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104800.1:46575313-46577343
-
GO:0016114

TkA01G073790

Terpenoid metabolismTerpenoid metabolismHigh · score 8
Source IDTkA01G073790
LocationCM104799.1:158178648-158181492 +
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010436 carotenoid dioxygenase activity molecular_function

LXL04_005252

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source ID-
LocationCM104799.1:158912413-158912804 +
EvidenceGOExpressionLocalizationSwiss-ProtPPICoexpression
Key evidencego:0010311 lateral root formation biological_process

TkA01G071950

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G071950
LocationCM104799.1:159048185-159053624 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006979 response to oxidative stress biological_process

TkA01G053380

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G053380;TkA01G053400;TkA03G231260
LocationCM104799.1:163134407-163141202 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA01G018390

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G018390
LocationCM104799.1:172900148-172900978 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G006560

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA01G006560
LocationCM104799.1:175871285-175874519 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA03G084520

Latex/root related candidatesLatex/root associated candidatesHigh · score 8
Source IDTkA03G084520
LocationCM104800.1:28454435-28454839 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA02G565680

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA02G565680
LocationCM104800.1:33697739-33699470 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA03G137290

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA03G137290
LocationCM104800.1:39506769-39513818 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA03G164130

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 8
Source IDTkA03G164130;TkA03G169300
LocationCM104800.1:46575313-46577343 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.