Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 177 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
LXL04_021550
TK1151: -
OH-1004: LXL04_021550
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:132245169-132245495
+
go:0009651 response to salt stress biological_process
TkA05G407520
TK1151: TkA05G407520;TkA06G476300;TkA08G003540
OH-1004: LXL04_021575
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:132610192-132611583
-
go:0048364 root development biological_process
TkAUNG070040
TK1151: TkAUNG070040;TkA01G598720;TkA05G079250
OH-1004: LXL04_021674
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:134666514-134670947
-
go:0048364 root development biological_process
TkA05G415840
TK1151: TkA05G415840
OH-1004: LXL04_021686
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:135142118-135143722
-
go:0006970 response to osmotic stress biological_process
TkA05G421100
TK1151: TkA05G421100;TkA05G422530;TkA05G423390
OH-1004: LXL04_021788
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:137002807-137006387
-
go:0006970 response to osmotic stress biological_process
TkA05G421600
TK1151: TkA05G421600;TkA05G421730;TkA05G423490
OH-1004: LXL04_021794
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationSwiss-ProtCoexpression CM104802.1:137032007-137034477
-
go:0009651 response to salt stress biological_process
TkAUNG085990
TK1151: TkAUNG085990;TkA03G277320;TkA03G483720;TkA05G429130
OH-1004: LXL04_021847
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:138563694-138565451
-
go:0009651 response to salt stress biological_process
TkA04G169020
TK1151: TkA04G169020;TkA05G429720
OH-1004: LXL04_021868
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:138909726-138913303
-
go:0009611 response to wounding biological_process
TkA05G429540
TK1151: TkA05G429540
OH-1004: LXL04_021873
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:138970283-138974496
+
go:0009611 response to wounding biological_process
TkAUNG024690
TK1151: TkAUNG024690;TkA08G354230
OH-1004: LXL04_021889
Terpenoid metabolism
Terpenoid metabolism
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:139651413-139655754
-
go:0016114 terpenoid biosynthetic process biological_process

LXL04_021550

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source ID-
LocationCM104802.1:132245169-132245495 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA05G407520

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G407520;TkA06G476300;TkA08G003540
LocationCM104802.1:132610192-132611583 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

TkAUNG070040

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkAUNG070040;TkA01G598720;TkA05G079250
LocationCM104802.1:134666514-134670947 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0048364 root development biological_process

TkA05G415840

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G415840
LocationCM104802.1:135142118-135143722 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA05G421100

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G421100;TkA05G422530;TkA05G423390
LocationCM104802.1:137002807-137006387 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA05G421600

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G421600;TkA05G421730;TkA05G423490
LocationCM104802.1:137032007-137034477 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidencego:0009651 response to salt stress biological_process

TkAUNG085990

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkAUNG085990;TkA03G277320;TkA03G483720;TkA05G429130
LocationCM104802.1:138563694-138565451 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009651 response to salt stress biological_process

TkA04G169020

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA04G169020;TkA05G429720
LocationCM104802.1:138909726-138913303 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkA05G429540

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G429540
LocationCM104802.1:138970283-138974496 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009611 response to wounding biological_process

TkAUNG024690

Terpenoid metabolismTerpenoid metabolismMedium · score 4
Source IDTkAUNG024690;TkA08G354230
LocationCM104802.1:139651413-139655754 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0016114 terpenoid biosynthetic process biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.